The astropy project: sustaining and growing a community-oriented open-source project and the latest major release (v5. 0) of the core package AM Price-Whelan, PL Lim, N Earl, N Starkman, L Bradley, DL Shupe, ... The Astrophysical Journal 935 (2), 167, 2022 | 1465 | 2022 |
SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN) VJ Hall, S Foulkes, A Charlett, A Atti, EJM Monk, R Simmons, E Wellington, ... The Lancet 397 (10283), 1459-1469, 2021 | 674 | 2021 |
Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia PJ Conn, CW Lindsley, CK Jones Trends in pharmacological sciences 30 (1), 25-31, 2009 | 413 | 2009 |
Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders PJ Conn, CK Jones, CW Lindsley Trends in pharmacological sciences 30 (3), 148-155, 2009 | 311 | 2009 |
Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats CK Jones, AE Brady, AA Davis, Z Xiang, M Bubser, MN Tantawy, AS Kane, ... Journal of Neuroscience 28 (41), 10422-10433, 2008 | 283 | 2008 |
Muscarinic and nicotinic acetylcholine receptor agonists and allosteric modulators for the treatment of schizophrenia CK Jones, N Byun, M Bubser Neuropsychopharmacology 37 (1), 16-42, 2012 | 253 | 2012 |
Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4 CM Niswender, KA Johnson, CD Weaver, CK Jones, Z Xiang, Q Luo, ... Molecular pharmacology 74 (5), 1345-1358, 2008 | 232 | 2008 |
Efficacy of duloxetine, a potent and balanced serotonergic and noradrenergic reuptake inhibitor, in inflammatory and acute pain models in rodents CK Jones, SC Peters, HE Shannon Journal of Pharmacology and Experimental Therapeutics 312 (2), 726-732, 2005 | 212 | 2005 |
Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in rats AE Brady, CK Jones, TM Bridges, JP Kennedy, AD Thompson, ... Journal of Pharmacology and Experimental Therapeutics 327 (3), 941-953, 2008 | 209 | 2008 |
Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of … AL Rodriguez, MD Grier, CK Jones, EJ Herman, AS Kane, RL Smith, ... Molecular pharmacology 78 (6), 1105-1123, 2010 | 206 | 2010 |
Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic-and anxiolytic-like effects in mice R Galici, CK Jones, K Hemstapat, Y Nong, NG Echemendia, LC Williams, ... Journal of Pharmacology and Experimental Therapeutics 318 (1), 173-185, 2006 | 195 | 2006 |
The role of estrogen in brain and cognitive aging JK Russell, CK Jones, PA Newhouse Neurotherapeutics 16 (3), 649-665, 2019 | 144 | 2019 |
A novel selective muscarinic acetylcholine receptor subtype 1 antagonist reduces seizures without impairing hippocampus-dependent learning DJ Sheffler, R Williams, TM Bridges, Z Xiang, AS Kane, NE Byun, ... Molecular pharmacology 76 (2), 356-368, 2009 | 141 | 2009 |
Selective Activation of M4 Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents M Bubser, TM Bridges, D Dencker, RW Gould, M Grannan, MJ Noetzel, ... ACS chemical neuroscience 5 (10), 920-942, 2014 | 134 | 2014 |
Antipsychotic-like effects of M4 positive allosteric modulators are mediated by CB2 receptor-dependent inhibition of dopamine release DJ Foster, JM Wilson, DH Remke, MS Mahmood, MJ Uddin, J Wess, ... Neuron 91 (6), 1244-1252, 2016 | 130 | 2016 |
Biased mGlu5-positive allosteric modulators provide in vivo efficacy without potentiating mGlu5 modulation of NMDAR currents JM Rook, Z Xiang, X Lv, A Ghoshal, JW Dickerson, TM Bridges, ... Neuron 86 (4), 1029-1040, 2015 | 129 | 2015 |
Muscarinic receptor pharmacology and circuitry for the modulation of cognition M Bubser, N Byun, MR Wood, CK Jones Muscarinic receptors, 121-166, 2012 | 129 | 2012 |
Functional impact of allosteric agonist activity of selective positive allosteric modulators of metabotropic glutamate receptor subtype 5 in regulating central nervous system … MJ Noetzel, JM Rook, PN Vinson, HP Cho, E Days, Y Zhou, AL Rodriguez, ... Molecular pharmacology 81 (2), 120-133, 2012 | 127 | 2012 |
Muscarinic cholinergic modulation of prepulse inhibition of the acoustic startle reflex CK Jones, HE Shannon Journal of Pharmacology and Experimental Therapeutics 294 (3), 1017-1023, 2000 | 127 | 2000 |
Discovery of the first highly M5-preferring muscarinic acetylcholine receptor ligand, an M5 positive allosteric modulator derived from a series of 5-trifluoromethoxy N-benzyl … TM Bridges, JE Marlo, CM Niswender, CK Jones, SB Jadhav, PR Gentry, ... Journal of medicinal chemistry 52 (11), 3445-3448, 2009 | 125 | 2009 |