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Assaf Alon
Assaf Alon
Harvard Medical School
Verified email at hms.harvard.edu
Title
Cited by
Cited by
Year
Identification of the gene that codes for the σ2 receptor
A Alon, HR Schmidt, MD Wood, JJ Sahn, SF Martin, AC Kruse
Proceedings of the National Academy of Sciences 114 (27), 7160-7165, 2017
2782017
Improved molecular replacement by density-and energy-guided protein structure optimization
F DiMaio, TC Terwilliger, RJ Read, A Wlodawer, G Oberdorfer, U Wagner, ...
Nature 473 (7348), 540-543, 2011
2642011
A secreted disulfide catalyst controls extracellular matrix composition and function
T Ilani, A Alon, I Grossman, B Horowitz, E Kartvelishvily, SR Cohen, ...
Science 341 (6141), 74-76, 2013
1632013
Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2
TA Tummino, VV Rezelj, B Fischer, A Fischer, MJ O’meara, B Monel, ...
Science 373 (6554), 541-547, 2021
1582021
COVID-19: famotidine, histamine, mast cells, and mechanisms
RW Malone, P Tisdall, P Fremont-Smith, Y Liu, XP Huang, KM White, ...
Frontiers in Pharmacology 12, 633680, 2021
1462021
Structures of the σ2 receptor enable docking for bioactive ligand discovery
A Alon, J Lyu, JM Braz, TA Tummino, V Craik, MJ O’Meara, CM Webb, ...
Nature 600 (7890), 759-764, 2021
1272021
AbDesign: An algorithm for combinatorial backbone design guided by natural conformations and sequences
GD Lapidoth, D Baran, GM Pszolla, C Norn, A Alon, MD Tyka, ...
Proteins: Structure, Function, and Bioinformatics 83 (8), 1385-1406, 2015
1092015
Human quiescin-sulfhydryl oxidase, QSOX1: probing internal redox steps by mutagenesis
EJ Heckler, A Alon, D Fass, C Thorpe
Biochemistry 47 (17), 4955-4963, 2008
912008
The dynamic disulphide relay of quiescin sulphydryl oxidase
A Alon, I Grossman, Y Gat, VK Kodali, F DiMaio, T Mehlman, G Haran, ...
Nature 488 (7411), 414-418, 2012
902012
QSOX contains a pseudo-dimer of functional and degenerate sulfhydryl oxidase domains
A Alon, EJ Heckler, C Thorpe, D Fass
FEBS letters 584 (8), 1521-1525, 2010
552010
An inhibitory antibody blocks the first step in the dithiol/disulfide relay mechanism of the enzyme QSOX1
I Grossman, A Alon, T Ilani, D Fass
Journal of molecular biology 425 (22), 4366-4378, 2013
342013
Dormant spores sense amino acids through the B subunits of their germination receptors
L Artzi, A Alon, KP Brock, AG Green, A Tam, FH Ramírez-Guadiana, ...
Nature Communications 12 (1), 6842, 2021
262021
The SpoVA membrane complex is required for dipicolinic acid import during sporulation and export during germination
Y Gao, RDC Barajas-Ornelas, JD Amon, FH Ramírez-Guadiana, A Alon, ...
Genes & Development 36 (9-10), 634-646, 2022
222022
Structural perspectives on sigma-1 receptor function
A Alon, H Schmidt, S Zheng, AC Kruse
Sigma Receptors: Their Role in Disease and as Therapeutic Targets, 5-13, 2017
182017
Exploring ORFan domains in giant viruses: structure of mimivirus sulfhydryl oxidase R596
M Hakim, D Ezerina, A Alon, O Vonshak, D Fass
PLoS One 7 (11), e50649, 2012
182012
cis‐Proline mutants of quiescin sulfhydryl oxidase 1 with altered redox properties undermine extracellular matrix integrity and cell adhesion in fibroblast cultures
G Javitt, I Grossman‐Haham, A Alon, E Resnick, Y Mutsafi, T Ilani, D Fass
Protein Science 28 (1), 228-238, 2019
132019
Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2
TA Tummino, VV Rezelj, B Fischer, A Fischer, MJ O’Meara, B Monel, ...
bioRxiv, 2021
92021
Phylogenetics and enzymology of plant quiescin sulfhydryl oxidase
K Limor-Waisberg, A Alon, T Mehlman, D Fass
FEBS letters 586 (23), 4119-4125, 2012
92012
Crystal structures of the σ2 receptor template large-library docking for selective chemotypes active in vivo
A Alon, J Lyu, JM Braz, TA Tummino, V Craik, MJ O’Meara, CM Webb, ...
bioRxiv, 2021.04. 29.441652, 2021
72021
Antagonistic nanobodies reveal mechanism of GSDMD pore formation and unexpected therapeutic potential
LDJ Schiffelers, S Normann, SC Binder, E Hagelauer, A Kopp, A Alon, ...
bioRxiv, 2023.04. 20.537718, 2023
32023
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