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Francesco Destro
Francesco Destro
Postdoctoral Associate, MIT
Email verificata su mit.edu
Titolo
Citata da
Citata da
Anno
A review on the modernization of pharmaceutical development and manufacturing–Trends, perspectives, and the role of mathematical modeling
F Destro, M Barolo
International Journal of Pharmaceutics 620, 121715, 2022
722022
A hybrid framework for process monitoring: Enhancing data-driven methodologies with state and parameter estimation
F Destro, P Facco, SG Munoz, F Bezzo, M Barolo
Journal of Process Control 92, 333-351, 2020
362020
Mathematical modeling and digital design of an intensified filtration-washing-drying unit for pharmaceutical continuous manufacturing
F Destro, I Hur, V Wang, M Abdi, X Feng, E Wood, S Coleman, P Firth, ...
Chemical engineering science 244, 116803, 2021
272021
Powder composition monitoring in continuous pharmaceutical solid-dosage form manufacturing using state estimation–Proof of concept
F Destro, SG Muñoz, F Bezzo, M Barolo
International Journal of Pharmaceutics 605, 120808, 2021
152021
A benchmark simulator for quality-by-design and quality-by-control studies in continuous pharmaceutical manufacturing‒Intensified filtration-drying of crystallization slurries
F Destro, ZK Nagy, M Barolo
Computers & chemical engineering 163, 107809, 2022
132022
Mechanistic modeling explains the production dynamics of recombinant adeno-associated virus with the baculovirus expression vector system
F Destro, J Joseph, P Srinivasan, JM Kanter, C Neufeld, JM Wolfrum, ...
Molecular Therapy-Methods & Clinical Development 30, 122-146, 2023
122023
Quality‐by‐control of intensified continuous filtration‐drying of active pharmaceutical ingredients
F Destro, M Barolo, ZK Nagy
AIChE Journal 69 (2), e17926, 2023
102023
Monitoring a segmented fluid bed dryer by hybrid data-driven/knowledge-driven modeling
F Destro, AJ Salmon, P Facco, CC Pantelides, F Bezzo, M Barolo
IFAC-PapersOnLine 53 (2), 11638-11643, 2020
102020
Analysis of Poly (ethylene terephthalate) degradation kinetics of evolved IsPETase variants using a surface crowding model
EZL Zhong-Johnson, Z Dong, CT Canova, F Destro, M Cañellas, ...
Journal of Biological Chemistry 300 (3), 2024
82024
Digital design of an integrated purification system for continuous pharmaceutical manufacturing
I Hur, D Casas-Orozco, DJ Laky, F Destro, ZK Nagy
Chemical Engineering Science 285, 119534, 2024
42024
Integrated synthesis, crystallization, filtration, and drying of active pharmaceutical ingredients: a model-based digital design framework for process optimization and control
DJ Laky, D Casas-Orozco, F Destro, M Barolo, GV Reklaitis, ZK Nagy
Optimization of Pharmaceutical Processes, 253-287, 2022
42022
Continuous integrated filtration, washing and drying of aspirin: digital design of a novel intensified unit
F Destro, V Wang, M Abdi, X Feng, E Wood, S Coleman, P Firth, A Barton, ...
IFAC-PapersOnLine 54 (3), 134-139, 2021
32021
Advanced methodologies for model-based optimization and control of pharmaceutical processes
F Destro, PK Inguva, P Srisuma, RD Braatz
Current Opinion in Chemical Engineering 45, 101035, 2024
12024
Efficient simulation of viral transduction and propagation for biomanufacturing
F Destro, RD Braatz
ACS Synthetic Biology, 2024
12024
The state of technological advancement to address challenges in the manufacture of rAAV gene therapies
F Destro, W Wu, P Srinivasan, J Joseph, V Bal, C Neufeld, JM Wolfrum, ...
Biotechnology Advances, 108433, 2024
2024
Mechanistic Modeling to Enhance Production of Recombinant Adeno-Associated Virus with Insect Cells
F Destro, J Joseph, P Srinivasan, J Kanter, C Neufeld, JM Wolfrum, ...
2023 AIChE Annual Meeting, 2023
2023
Efficient Numerical Strategies for Multidimensional Population Balance Models and Transport Equations
P Inguva, F Destro, R Braatz
2023 AIChE Annual Meeting, 2023
2023
Model-Based Optimization of Continuous Manufacturing with the Baculovirus Expression Vector System
F Destro, J Joseph, L Paoli, P Srinivasan, J Kanter, C Neufeld, ...
2023 AIChE Annual Meeting, 2023
2023
Introducing ContCarSim, a benchmark simulator for design and control of continuous integrated filtration-drying of crystallization slurries
F Destro, M Barolo, ZK Nagy
2022 AIChE Annual Meeting, 2023
2023
Model-based monitoring of an intensified unit for continuous pharmaceutical filtration-drying
F Destro, M Barolo, ZK Nagy
Computer Aided Chemical Engineering 49, 1405-1410, 2022
2022
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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