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Jesus F. Barajas, Ph.D.
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Evolution-guided engineering of small-molecule biosensors
T Snoek, EK Chaberski, F Ambri, S Kol, SP Bjørn, B Pang, JF Barajas, ...
Nucleic acids research 48 (1), e3-e3, 2020
1192020
Engineered polyketides: Synergy between protein and host level engineering
JF Barajas, JM Blake-Hedges, CB Bailey, S Curran, JD Keasling
Synthetic and systems biotechnology 2 (3), 147-166, 2017
1022017
The Arabidopsis Cell Cycle Checkpoint Regulators TANMEI/ALT2 and ATR Mediate the Active Process of Aluminum-Dependent Root Growth Inhibition
CD Nezames, CA Sjogren, JF Barajas, PB Larsen
The Plant Cell 24 (2), 608-621, 2012
822012
Development of Next Generation Synthetic Biology Tools for Use in Streptomyces venezuelae
RM Phelan, D Sachs, SJ Petkiewicz, JF Barajas, JM Blake-Hedges, ...
ACS synthetic biology 6 (1), 159-166, 2017
762017
Development of a transcription factor-based lactam biosensor
J Zhang, JF Barajas, M Burdu, TL Ruegg, B Dias, JD Keasling
ACS synthetic biology 6 (3), 439-445, 2017
742017
Application of an Acyl-CoA Ligase from Streptomyces aizunensis for Lactam Biosynthesis
J Zhang, JF Barajas, M Burdu, G Wang, EE Baidoo, JD Keasling
ACS Synthetic Biology 6 (5), 884-890, 2017
682017
Comprehensive structural and biochemical analysis of the terminal myxalamid reductase domain for the engineered production of primary alcohols
JF Barajas, RM Phelan, AJ Schaub, JT Kliewer, PJ Kelly, DR Jackson, ...
Chemistry & biology 22 (8), 1018-1029, 2015
622015
Massively Parallel Fitness Profiling Reveals Multiple Novel Enzymes in Pseudomonas putida Lysine Metabolism
MG Thompson, JM Blake-Hedges, P Cruz-Morales, JF Barajas, ...
MBio 10 (3), 10.1128/mbio. 02577-18, 2019
61*2019
Massively Parallel Fitness Profiling Reveals Multiple Novel Enzymes in Pseudomonas putida Lysine Metabolism
MG Thompson, JM Blake-Hedges, P Cruz-Morales, JF Barajas, ...
MBio 10 (3), 10.1128/mbio. 02577-18, 2019
592019
Molecular basis for interactions between an acyl carrier protein and a ketosynthase
JC Milligan, DJ Lee, DR Jackson, AJ Schaub, J Beld, JF Barajas, JJ Hale, ...
Nature chemical biology 15 (7), 669-671, 2019
502019
Isolation and characterization of novel mutations in the pSC101 origin that increase copy number
MG Thompson, N Sedaghatian, JF Barajas, M Wehrs, CB Bailey, ...
Scientific reports 8 (1), 1590, 2018
402018
Identification, Characterization, and Application of a Highly Sensitive Lactam Biosensor from Pseudomonas putida
MG Thompson, AN Pearson, JF Barajas, P Cruz-Morales, N Sedaghatian, ...
ACS synthetic biology 9 (1), 53-62, 2019
362019
Structural and functional analysis of two di-domain aromatase/cyclases from type II polyketide synthases
G Caldara-Festin, DR Jackson, JF Barajas, TR Valentic, AB Patel, ...
Proceedings of the National Academy of Sciences 112 (50), E6844-E6851, 2015
352015
Modeling linear and cyclic PKS intermediates through atom replacement
G Shakya, H Rivera Jr, DJ Lee, MJ Jaremko, JJ La Clair, DT Fox, ...
Journal of the American Chemical Society 136 (48), 16792-16799, 2014
302014
Polyketide mimetics yield structural and mechanistic insights into product template domain function in nonreducing polyketide synthases
JF Barajas, G Shakya, G Moreno, H Rivera Jr, DR Jackson, CL Topper, ...
Proceedings of the National Academy of Sciences 114 (21), E4142-E4148, 2017
272017
Structural insights into anthranilate priming during type II polyketide biosynthesis
DR Jackson, SS Tu, MC Nguyen, JF Barajas, AJ Schaub, D Krug, ...
ACS chemical biology 11 (1), 95-103, 2016
272016
Chemoinformatic-guided engineering of polyketide synthases
A Zargar, R Lal, L Valencia, J Wang, TWH Backman, P Cruz-Morales, ...
Journal of the American Chemical Society 142 (22), 9896-9901, 2020
242020
Biochemical Characterization of β‐Amino Acid Incorporation in Fluvirucin B2 Biosynthesis
JF Barajas, A Zargar, B Pang, VT Benites, J Gin, EEK Baidoo, CJ Petzold, ...
ChemBioChem 19 (13), 1391-1395, 2018
142018
Structural and biochemical analysis of protein–protein interactions between the acyl‐carrier protein and product template domain
JF Barajas, K Finzel, TR Valentic, G Shakya, N Gamarra, D Martinez, ...
Angewandte Chemie International Edition 55 (42), 13005-13009, 2016
142016
Heterologous Gene Expression of N-Terminally Truncated Variants of LipPks1 Suggests a Functionally Critical Structural Motif in the N-terminus of Modular …
S Yuzawa, CB Bailey, T Fujii, R Jocic, JF Barajas, VT Benites, ...
ACS chemical biology 12 (11), 2725-2729, 2017
122017
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Articles 1–20