| Small molecule protein–protein interaction inhibitors as CNS therapeutic agents: current progress and future hurdles LL Blazer, RR Neubig Neuropsychopharmacology 34 (1), 126-141, 2009 | 224 | 2009 |
| Regulators of G protein signaling proteins as targets for drug discovery B Sjögren, LL Blazer, RR Neubig Progress in molecular biology and translational science 91, 81-119, 2010 | 112 | 2010 |
| Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins LL Blazer, DL Roman, A Chung, MJ Larsen, BM Greedy, SM Husbands, ... Molecular pharmacology 78 (3), 524-533, 2010 | 103 | 2010 |
| A nanomolar-potency small molecule inhibitor of regulator of G-protein signaling proteins LL Blazer, H Zhang, EM Casey, SM Husbands, RR Neubig Biochemistry 50 (15), 3181-3192, 2011 | 87 | 2011 |
| Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice Y Tao, M Mis, L Blazer, M Ustav, Z Steinhart, R Chidiac, E Kubarakos, ... Elife 8, e46134, 2019 | 75 | 2019 |
| Allosteric Inhibition of the Regulator of G Protein Signaling–Gα Protein–Protein Interaction by CCG-4986 DL Roman, LL Blazer, CA Monroy, RR Neubig Molecular pharmacology 78 (3), 360-365, 2010 | 60 | 2010 |
| Small molecule inhibitors of regulators of G protein signaling (RGS) proteins EM Turner, LL Blazer, RR Neubig, SM Husbands ACS medicinal chemistry letters 3 (2), 146-150, 2012 | 57 | 2012 |
| Immunoproteomics JL Hess, L Blazer, T Romer, L Faber, RM Buller, MDP Boyle Journal of Chromatography B 815 (1-2), 65-75, 2005 | 56 | 2005 |
| Selectivity and anti-Parkinson’s potential of thiadiazolidinone RGS4 inhibitors LL Blazer, AJ Storaska, EM Jutkiewicz, EM Turner, M Calcagno, SM Wade, ... ACS chemical neuroscience 6 (6), 911-919, 2015 | 52 | 2015 |
| Blockade of TGF-β signaling with novel synthetic antibodies limits immune exclusion and improves chemotherapy response in metastatic ovarian cancer models D Newsted, S Banerjee, K Watt, S Nersesian, P Truesdell, LL Blazer, ... Oncoimmunology 8 (2), e1539613, 2019 | 47 | 2019 |
| A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties Z Pavlovic, JJ Adams, LL Blazer, AK Gakhal, N Jarvik, Z Steinhart, ... mAbs 10 (8), 1157-1167, 2018 | 46 | 2018 |
| Use of flow cytometric methods to quantify protein‐protein interactions LL Blazer, DL Roman, MR Muxlow, RR Neubig Current protocols in cytometry 51 (1), 13.11. 1-13.11. 15, 2010 | 45 | 2010 |
| The role of the VPS4A-exosome pathway in the intrinsic egress route of a DNA-binding anticancer drug VY Chen, MM Posada, LL Blazer, T Zhao, GR Rosania Pharmaceutical research 23, 1687-1695, 2006 | 39 | 2006 |
| PR Domain-Containing Protein 7 (PRDM7) is a Histone 3 Lysine 4 Trimethyltransferase LL Blazer, E Lima-Fernandes, E Gibson, MS Eram, P Loppnau, ... Journal of Biological Chemistry 291 (26), 13509-13519, 2016 | 36 | 2016 |
| Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b S Hu, S Liu, Y Bian, M Poddar, S Singh, C Cao, J McGaughey, A Bell, ... Cell Reports Medicine 3 (10), 2022 | 34 | 2022 |
| Tetravalent SARS-CoV-2 neutralizing antibodies show enhanced potency and resistance to escape mutations S Miersch, Z Li, R Saberianfar, M Ustav, JB Case, L Blazer, C Chen, W Ye, ... Journal of molecular biology 433 (19), 167177, 2021 | 33 | 2021 |
| Novel peptide ligands of RGS4 from a focused one‐bead, one‐compound library RA Roof, K Sobczyk‐Kojiro, AJ Turbiak, DL Roman, ID Pogozheva, ... Chemical biology & drug design 72 (2), 111-119, 2008 | 33 | 2008 |
| A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy R Chidiac, M Abedin, G Macleod, A Yang, PE Thibeault, LL Blazer, ... EMBO Molecular Medicine 13 (7), e13977, 2021 | 32 | 2021 |
| Discovery of a chemical probe for PRDM9 A Allali-Hassani, MM Szewczyk, D Ivanochko, SL Organ, J Bok, JSY Ho, ... Nature communications 10 (1), 5759, 2019 | 30 | 2019 |
| A covalent peptide inhibitor of RGS4 identified in a focused one-bead, one compound library screen RA Roof, DL Roman, ST Clements, K Sobczyk-Kojiro, LL Blazer, S Ota, ... BMC pharmacology 9, 1-11, 2009 | 30 | 2009 |
