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Piero Pingitore
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The MBOAT7-TMC4 variant rs641738 increases risk of nonalcoholic fatty liver disease in individuals of European descent
RM Mancina, P Dongiovanni, S Petta, P Pingitore, M Meroni, R Rametta, ...
Gastroenterology 150 (5), 1219-1230. e6, 2016
6162016
PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells
C Pirazzi, L Valenti, BM Motta, P Pingitore, K Hedfalk, RM Mancina, ...
Human molecular genetics 23 (15), 4077-4085, 2014
3692014
Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver
P Dongiovanni, S Stender, A Pietrelli, RM Mancina, A Cespiati, S Petta, ...
Journal of internal medicine 283 (4), 356-370, 2018
2922018
Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of function
P Pingitore, C Pirazzi, RM Mancina, BM Motta, C Indiveri, A Pujia, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014
2192014
Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice
D Lindén, A Ahnmark, P Pingitore, E Ciociola, I Ahlstedt, AC Andréasson, ...
Molecular metabolism 22, 49-61, 2019
1742019
PNPLA3 overexpression results in reduction of proteins predisposing to fibrosis
P Pingitore, P Dongiovanni, BM Motta, M Meroni, SM Lepore, ...
Human molecular genetics 25 (23), 5212-5222, 2016
1312016
The rs2294918 E434K variant modulates patatin‐like phospholipase domain‐containing 3 expression and liver damage
B Donati, BM Motta, P Pingitore, M Meroni, A Pietrelli, A Alisi, S Petta, ...
Hepatology 63 (3), 787-798, 2016
1252016
Human multilineage 3D spheroids as a model of liver steatosis and fibrosis
P Pingitore, K Sasidharan, M Ekstrand, S Prill, D Lindén, S Romeo
International journal of molecular sciences 20 (7), 1629, 2019
1072019
The role of PNPLA3 in health and disease
P Pingitore, S Romeo
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019
982019
The TM6SF2 E167K genetic variant induces lipid biosynthesis and reduces apolipoprotein B secretion in human hepatic 3D spheroids
S Prill, A Caddeo, G Baselli, O Jamialahmadi, P Dongiovanni, R Rametta, ...
Scientific reports 9 (1), 11585, 2019
972019
Liver transcriptomics highlights interleukin-32 as novel NAFLD-related cytokine and candidate biomarker
GA Baselli, P Dongiovanni, R Rametta, M Meroni, S Pelusi, M Maggioni, ...
Gut 69 (10), 1855-1866, 2020
782020
Large scale production of the active human ASCT2 (SLC1A5) transporter in Pichia pastoris—Functional and kinetic asymmetry revealed in proteoliposomes
P Pingitore, L Pochini, M Scalise, M Galluccio, K Hedfalk, C Indiveri
Biochimica Et Biophysica Acta (BBA)-Biomembranes 1828 (9), 2238-2246, 2013
752013
Transport mechanism and regulatory properties of the human amino acid transporter ASCT2 (SLC1A5)
M Scalise, L Pochini, S Panni, P Pingitore, K Hedfalk, C Indiveri
Amino Acids 46, 2463-2475, 2014
732014
MBOAT7 is anchored to endomembranes by six transmembrane domains
A Caddeo, O Jamialahmadi, G Solinas, A Pujia, RM Mancina, P Pingitore, ...
Journal of Structural Biology 206 (3), 349-360, 2019
562019
Telomerase reverse transcriptase germline mutations and hepatocellular carcinoma in patients with nonalcoholic fatty liver disease
B Donati, A Pietrelli, P Pingitore, P Dongiovanni, A Caddeo, L Walker, ...
Cancer medicine 6 (8), 1930-1940, 2017
532017
Cysteine is not a substrate but a specific modulator of human ASCT2 (SLC1A5) transporter
M Scalise, L Pochini, P Pingitore, K Hedfalk, C Indiveri
FEBS letters 589 (23), 3617-3623, 2015
502015
Identification and characterization of two novel mutations in the LPL gene causing type I hyperlipoproteinemia
P Pingitore, SM Lepore, C Pirazzi, RM Mancina, BM Motta, L Valenti, ...
Journal of clinical lipidology 10 (4), 816-823, 2016
372016
DEPDC5 variants increase fibrosis progression in Europeans with chronic hepatitis C virus infection
MA Burza, BM Motta, RM Mancina, P Pingitore, C Pirazzi, SM Lepore, ...
Hepatology 63 (2), 418-427, 2016
372016
PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver Enzymes
RM Mancina, R Spagnuolo, M Milano, S Brogneri, A Morrone, C Cosco, ...
Inflammatory Bowel Diseases 22 (1), 134-140, 2016
352016
Discovery and Targeting of the Signaling Controls of PNPLA3 to Effectively Reduce Transcription, Expression, and Function in Pre-Clinical NAFLD/NASH Settings
BE Schwartz, V Rajagopal, C Smith, E Cohick, G Whissell, M Gamboa, ...
Cells 9 (10), 2247, 2020
312020
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