Claudio Isella
Claudio Isella
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A molecularly annotated platform of patient-derived xenografts (“xenopatients”) identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer
A Bertotti, G Migliardi, F Galimi, F Sassi, D Torti, C Isella, D CorÓ, ...
Cancer discovery 1 (6), 508-523, 2011
Stromal contribution to the colorectal cancer transcriptome
C Isella, A Terrasi, SE Bellomo, C Petti, G Galatola, A Muratore, A Mellano, ...
Nature genetics 47 (4), 312-319, 2015
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets
E Medico, M Russo, G Picco, C Cancelliere, E Valtorta, G Corti, ...
Nature communications 6 (1), 1-10, 2015
MiR-1 downregulation cooperates with MACC1 in promoting MET overexpression in human colon cancer
C Migliore, V Martin, VP Leoni, A Restivo, L Atzori, A Petrelli, C Isella, ...
Clinical Cancer Research 18 (3), 737-747, 2012
Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer
C Isella, F Brundu, SE Bellomo, F Galimi, E Zanella, R Porporato, C Petti, ...
Nature communications 8 (1), 1-16, 2017
Genetic and expression analysis of MET, MACC1, and HGF in metastatic colorectal cancer: response to met inhibition in patient xenografts and pathologic correlations
F Galimi, D Torti, F Sassi, C Isella, D CorÓ, S Gastaldi, D Ribero, ...
Clinical cancer research 17 (10), 3146-3156, 2011
The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis
H Ling, K Pickard, C Ivan, C Isella, M Ikuo, R Mitter, R Spizzo, MD Bullock, ...
Gut 65 (6), 977-989, 2016
The thioxotriazole copper (II) complex A0 induces endoplasmic reticulum stress and paraptotic death in human cancer cells
S Tardito, C Isella, E Medico, L Marchio, E Bevilacqua, M Hatzoglou, ...
Journal of Biological Chemistry 284 (36), 24306-24319, 2009
A molecularly annotated platform of patient-derived xenografts (“xenopatients”) identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancerá…
A Bertotti, G Migliardi, F Galimi, F Sassi, D Torti, C Isella, D CorÓ, ...
Cancer Lett 345, 156-64, 2014
IGF2 is an actionable target that identifies a distinct subpopulation of colorectal cancer patients with marginal response to anti-EGFR therapies
ER Zanella, F Galimi, F Sassi, G Migliardi, F Cottino, SM Leto, B Lupo, ...
Science translational medicine 7 (272), 272ra12-272ra12, 2015
The miR-126 regulates angiopoietin-1 signaling and vessel maturation by targeting p85β
R Sessa, G Seano, L Di Blasio, PA Gagliardi, C Isella, E Medico, F Cotelli, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (10), 1925-1935, 2012
Increased lactate secretion by cancer cells sustains non-cell-autonomous adaptive resistance to MET and EGFR targeted therapies
M Apicella, E Giannoni, S Fiore, KJ Ferrari, D Fernßndez-PÚrez, C Isella, ...
Cell metabolism 28 (6), 848-865. e6, 2018
A molecular signature for Epithelial to Mesenchymal transition in a human colon cancer cell system is revealed by large-scale microarray analysis
T Joyce, D Cantarella, C Isella, E Medico, A Pintzas
Clinical & experimental metastasis 26 (6), 569-587, 2009
MicroRNA–mRNA interactions underlying colorectal cancer molecular subtypes
L Cantini, C Isella, C Petti, G Picco, S Chiola, E Ficarra, M Caselle, ...
Nature communications 6 (1), 1-12, 2015
MACC1 mRNA levels predict cancer recurrence after resection of colorectal cancer liver metastases
C Isella, A Mellano, F Galimi, C Petti, L Capussotti, M De Simone, ...
Annals of surgery 257 (6), 1089-1095, 2013
TNF-α promotes invasive growth through the MET signaling pathway
V Bigatto, F De Bacco, E Casanova, G Reato, L Lanzetti, C Isella, I Sarotto, ...
Molecular oncology 9 (2), 377-388, 2015
Neuropilin-1 upregulation elicits adaptive resistance to oncogene-targeted therapies
S Rizzolio, G Cagnoni, C Battistini, S Bonelli, C Isella, ...
The Journal of clinical investigation 128 (9), 3976-3990, 2018
Prospective patient stratification into robust cancer‐cell intrinsic subtypes from colorectal cancer biopsies
M Alderdice, SD Richman, S Gollins, JP Stewart, C Hurt, R Adams, ...
The Journal of pathology 245 (1), 19-28, 2018
Knock-in of oncogenic Kras does not transform mouse somatic cells but triggers a transcriptional response that classifies human cancers
S Arena, C Isella, M Martini, A De Marco, E Medico, A Bardelli
Cancer research 67 (18), 8468-8476, 2007
Primary breast cancer stem-like cells metastasise to bone, switch phenotype and acquire a bone tropism signature
S PatanŔ, C Grange, B Bussolati, C Isella, L Fontani, L Godio, M Cilli, ...
British journal of cancer 108 (12), 2525-2536, 2013
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