| From basic research to the clinic: innovative therapies for ALS and FTD in the pipeline RM Liscic, A Alberici, NJ Cairns, M Romano, E Buratti Molecular Neurodegeneration 15, 1-17, 2020 | 2 | 2020 |
| Synthesis, Cytotoxicity Evaluation and Computational Insights of Novel 1, 4-Diazepane-Based Sigma Ligands D Zampieri, S Fortuna, A Calabretti, M Romano, R Menegazzi, ... ACS Medicinal Chemistry Letters, 2019 | 3 | 2019 |
| Discovery of new potent dual sigma receptor/GluN2b ligands with antioxidant property as neuroprotective agents D Zampieri, S Fortuna, A Calabretti, M Romano, R Menegazzi, ... European journal of medicinal chemistry 180, 268-282, 2019 | 3 | 2019 |
| Dysregulation of TDP‐43 intracellular localization and early onset ALS are associated with a TARDBP S375G variant K Newell, F Paron, M Mompean, J Murrell, E Salis, C Stuani, G Pattee, ... Brain Pathology 29 (3), 397-413, 2019 | 5 | 2019 |
| L’ATEROSCLEROSI Č (ANCHE) UNA MALATTIA EPIGENETICA M Romano, FE Baralle Giornale Italiano dell’Arteriosclerosi 10 (3), 5-14, 2019 | | 2019 |
| New piperidine-based derivatives as sigma receptor ligands. Synthesis and pharmacological evaluation D Zampieri, M Romano, R Menegazzi, MG Mamolo Bioorganic & medicinal chemistry letters 28 (19), 3206-3209, 2018 | 1 | 2018 |
| Systematic analysis of gene expression profiles controlled by hnRNP Q and hnRNP R, two closely related human RNA binding proteins implicated in mRNA processing mechanisms S Cappelli, M Romano, E Buratti Frontiers in molecular biosciences 5, 79, 2018 | 5 | 2018 |
| In silico/in vitro studies of novel hot spot mutations in BCR-ABL1: A multidisciplinary approach to shed a new light on TKI resistance E Laurini, S Aulic, N Skoko, S Polez, M Baralle, M Romano, S Pricl Cancer Research 78 (13 Supplement), 2382-2382, 2018 | | 2018 |
| Essential role of hippocampal noradrenaline in the regulation of spatial working memory and TDP‐43 tissue pathology R Pintus, M Riggi, C Cannarozzo, A Valeri, G de Leo, M Romano, ... Journal of Comparative Neurology 526 (7), 1131-1147, 2018 | 5 | 2018 |
| RhoGAPp190: A potential player in tbph-mediated neurodegeneration in Drosophila S Langellotti, G Romano, F Feiguin, FE Baralle, M Romano Plos one 13 (4), e0195845, 2018 | 1 | 2018 |
| Role of the long non‐coding RNA growth arrest‐specific 5 in glucocorticoid response in children with inflammatory bowel disease M Lucafň, A Di Silvestre, M Romano, A Avian, R Antonelli, S Martelossi, ... Basic & clinical pharmacology & toxicology 122 (1), 87-93, 2018 | 31 | 2018 |
| Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells C Appocher, F Mohagheghi, S Cappelli, C Stuani, M Romano, F Feiguin, ... Nucleic acids research 45 (13), 8026-8045, 2017 | 41 | 2017 |
| Keratin14 mRNA expression in human pneumocytes during quiescence, repair and disease M Confalonieri, E Buratti, G Grassi, R Bussani, M Chilosi, R Farra, ... PloS one 12 (2), e0172130, 2017 | 6 | 2017 |
| Computer-assisted design, synthesis, binding and cytotoxicity assessments of new 1-(4-(aryl (methyl) amino) butyl)-heterocyclic sigma 1 ligands D Zampieri, L Vio, M Fermeglia, S Pricl, B Wünsch, D Schepmann, ... European journal of medicinal chemistry 121, 712-726, 2016 | 13 | 2016 |
| TBPH/TDP-43 modulates translation of Drosophila futsch mRNA through an UG-rich sequence within its 5′UTR M Romano, F Feiguin, E Buratti Brain research 1647, 50-56, 2016 | 18 | 2016 |
| Neuropathologic and neurobiologic characterization of early onset amyotrophic lateral sclerosis associated with a novel TDP43 S375G variant K Newell, B Ghetti, J Murrell, M Romano, E Salis, C Stuani, E Buratti JOURNAL OF NEUROCHEMISTRY 138, 370-370, 2016 | | 2016 |
| Antimycobacterial activity of new N1-[1-[1-aryl-3-[4-(1H-imidazol-1-yl) phenyl]-3-oxo] propyl]-pyridine-2-carboxamidrazone derivatives D Zampieri, MG Mamolo, L Vio, M Romano, N Skoko, M Baralle, V Pau, ... Bioorganic & medicinal chemistry letters 26 (14), 3287-3290, 2016 | 5 | 2016 |
| New neurogenic lipoic-based hybrids as innovative Alzheimer's drugs with σ-1 agonism and β-secretase inhibition M Estrada, C Pérez, E Soriano, E Laurini, M Romano, S Pricl, ... Future medicinal chemistry 8 (11), 1191-1207, 2016 | 24 | 2016 |
| A novel Drosophila model of TDP-43 proteinopathies: N-terminal sequences combined with the Q/N domain induce protein functional loss and locomotion defects S Langellotti, V Romano, G Romano, R Klima, F Feiguin, L Cragnaz, ... Disease models & mechanisms 9 (6), 659-669, 2016 | 14 | 2016 |
| Knockdown of MVK does not lead to changes in NALP3 expression or activation F Celsi, E Piscianz, M Romano, S Crovella Journal of Inflammation 12 (1), 1-5, 2015 | 11 | 2015 |
| TDP-43 affects splicing profiles and isoform production of genes involved in the apoptotic and mitotic cellular pathways L De Conti, MV Akinyi, R Mendoza-Maldonado, M Romano, M Baralle, ... Nucleic acids research 43 (18), 8990-9005, 2015 | 47 | 2015 |
| Exome sequencing of a colorectal cancer family reveals shared mutation pattern and predisposition circuitry along tumor pathways SH Suleiman, ME Koko, WH Nasir, O Elfateh, UK Elgizouli, MOE Abdallah, ... Frontiers in genetics 6, 288, 2015 | 9 | 2015 |
| A novel anti-aldolase C antibody specifically interacts with residues 85–102 of the protein S Langellotti, M Romano, C Guarnaccia, V Granata, S Orrů, A Zagari, ... MAbs 6 (3), 707-716, 2014 | 3 | 2014 |
| Evolutionarily conserved heterogeneous nuclear ribonucleoprotein (hnRNP) A/B proteins functionally interact with human and Drosophila TAR DNA-binding protein 43 (TDP-43) M Romano, E Buratti, G Romano, R Klima, LDB Belluz, C Stuani, ... Journal of Biological Chemistry 289 (10), 7121-7130, 2014 | 41 | 2014 |
| Targeting RNA binding proteins involved in neurodegeneration M Romano, E Buratti Journal of biomolecular screening 18 (9), 967-983, 2013 | 20 | 2013 |
| Role of pseudoexons and pseudointrons in human cancer M Romano, E Buratti, D Baralle International journal of cell biology 2013, 2013 | 19 | 2013 |
| TDP-43 high throughput screening analyses in neurodegeneration: advantages and pitfalls E Buratti, M Romano, FE Baralle Molecular and Cellular Neuroscience 56, 465-474, 2013 | 30 | 2013 |
| FLORBETAPIR F 18 FOR BRAIN IMAGING OF b-AMYLOID PLAQUES M Romano, E Buratti Drugs of Today 49 (3), 181-193, 2013 | 15 | 2013 |
| Tirasemtiv (CK-2017357) M Romano, E Buratti | 1 | 2013 |
| Small Cytoplasmic Ribonucleoproteins M Romano, E Buratti Brenner's Encyclopedia of Genetics (Second Edition), 463-465, 2013 | | 2013 |
| Drosophila answers to TDP-43 proteinopathies M Romano, F Feiguin, E Buratti Journal of amino acids 2012, 2012 | 23 | 2012 |
| Splicing in the RNA World E Buratti, M Romano, FE Baralle Alternative pre‐mRNA Splicing, 3-12, 2012 | 1 | 2012 |
| TDP-43 regulates Drosophila neuromuscular junctions growth by modulating Futsch/MAP1B levels and synaptic microtubules organization VK Godena, G Romano, M Romano, C Appocher, R Klima, E Buratti, ... PloS one 6 (3), e17808, 2011 | 112 | 2011 |
| TDP-43 regulates its mRNA levels through a negative feedback loop YM Ayala, S Laura De Conti, AD Vázquez, M Romano, A D'Ambrogio, ... The EMBO journal 30 (2), 277-288, 2011 | 436 | 2011 |
| G runs in Cystathionine β-Synthase c. 833C/c. 844_845ins68 mRNA are splicing silencers of pathogenic 3′ splice sites M Romano Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1799 (8), 568-574, 2010 | 6 | 2010 |
| Neuropeptides in saliva of subjects with burning mouth syndrome: a pilot study V Borelli, A Marchioli, R Di Taranto, M Romano, S Chiandussi, ... Oral diseases 16 (4), 365-374, 2010 | 63 | 2010 |
| Nuclear factor TDP‐43 can affect selected microRNA levels E Buratti, L De Conti, C Stuani, M Romano, M Baralle, F Baralle The FEBS journal 277 (10), 2268-2281, 2010 | 229 | 2010 |
| Functional mapping of the interaction between TDP-43 and hnRNP A2 in vivo A D’Ambrogio, E Buratti, C Stuani, C Guarnaccia, M Romano, YM Ayala, ... Nucleic acids research 37 (12), 4116-4126, 2009 | 208 | 2009 |
| Dissecting the splicing mechanism of the Drosophila editing enzyme; dADAR R Marcucci, M Romano, F Feiguin, MA O'Connell, FE Baralle Nucleic acids research 37 (5), 1663-1671, 2009 | 7 | 2009 |
| Thrombopoietin and its splicing variants: structure and functions in thrombopoiesis and beyond R Marcucci, M Romano Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1782 (7-8 …, 2008 | 22 | 2008 |
| Origin and evolution of the c. 844_845ins68/c. 833T> C mutations within the cystathionine β-synthase gene in great apes M Romano, MG Bacalini, EJ Verschoor, S Crovella, FE Baralle FEBS letters 582 (3), 423-426, 2008 | 4 | 2008 |
| Aberrant 5′ splice sites in human disease genes: mutation pattern, nucleotide structure and comparison of computational tools that predict their utilization E Buratti, M Chivers, J Královičová, M Romano, M Baralle, AR Krainer, ... Nucleic acids research 35 (13), 4250-4263, 2007 | 164 | 2007 |
| Complex splicing control of the human Thrombopoietin gene by intronic G runs R Marcucci, FE Baralle, M Romano Nucleic acids research 35 (1), 132-142, 2007 | 36 | 2007 |
| Photodynamic therapy of subfoveal choroidal neovascularization secondary to reticular pattern dystrophy: three-year results of an uncontrolled, prospective case series MB Parodi, T Liberali, M Pedio, PJ Francis, FC Piccolino, N Fiotti, ... American journal of ophthalmology 141 (6), 1152-1154, 2006 | 12 | 2006 |
| Human, Drosophila, and C. elegans TDP43: nucleic acid binding properties and splicing regulatory function YM Ayala, S Pantano, A D'Ambrogio, E Buratti, A Brindisi, C Marchetti, ... Journal of molecular biology 348 (3), 575-588, 2005 | 355 | 2005 |
| Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene PA Mercado, YM Ayala, M Romano, E Buratti, FE Baralle Nucleic acids research 33 (18), 6000-6010, 2005 | 260 | 2005 |
| Genetic studies on myeloperoxidase deficiency in Italy C Marchetti, P Patriarca, GP Solero, FE Baralle, M Romano Jpn. J. Infect. Dis 57 (5), S10-2, 2004 | 15 | 2004 |
| An exonic splicing enhancer offsets the atypical GU-rich 3′ splice site of human apolipoprotein A-II exon 3 P Arrisi-Mercado, M Romano, AF Muro, FE Baralle Journal of Biological Chemistry 279 (38), 39331-39339, 2004 | 19 | 2004 |
| Genetic characterization of myeloperoxidase deficiency in Italy C Marchetti, P Patriarca, GP Solero, FE Baralle, M Romano Human mutation 23 (5), 496-505, 2004 | 30 | 2004 |
| hnRNP H binding at the 5′ splice site correlates with the pathological effect of two intronic mutations in the NF-1 and TSHβ genes E Buratti, M Baralle, L De Conti, D Baralle, M Romano, YM Ayala, ... Nucleic acids research 32 (14), 4224-4236, 2004 | 95 | 2004 |
| Identification and subcellular localization of neuronal calcium sensor-1 (NCS-1) in human neutrophils and HL-60 cells C Brochetta, MG Perrotta, A Jeromin, M Romano, F Vita, MR Soranzo, ... Inflammation 27 (6), 361-372, 2003 | 8 | 2003 |
| Regulation of 3′ splice site selection in the 844ins68 polymorphism of the cystathionine β-synthase gene M Romano, R Marcucci, E Buratti, YM Ayala, G Sebastio, FE Baralle Journal of Biological Chemistry 277 (46), 43821-43829, 2002 | 51 | 2002 |
| Genetic heterogeneity in malattia leventinese L Toto, MB Parodi, F Baralle, G Casari, G Ravalico, M Romano Clinical genetics 62 (5), 399-403, 2002 | 10 | 2002 |
| Glycolipid analysis of different tissues and cerebrospinal fluid in type II Gaucher disease R Gornati, B Berra, G Montorfano, C Martini, G Ciana, P Ferrari, ... Journal of inherited metabolic disease 25 (1), 47-55, 2002 | 30 | 2002 |
| Minor role for BRCA2 (exon11) and p53 (exon 5–9) among Sudanese breast cancer patients MA Masri, NMA Seed, AH Fahal, M Romano, F Baralle, AM El Hassan, ... Breast cancer research and treatment 71 (2), 145-147, 2002 | 21 | 2002 |
| Nuclear factor TDP‐43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping E Buratti, T Dörk, E Zuccato, F Pagani, M Romano, FE Baralle The EMBO journal 20 (7), 1774-1784, 2001 | 635 | 2001 |
| Splicing of constitutive upstream introns is essential for the recognition of intra-exonic suboptimal splice sites in the thrombopoietin gene M Romano, R Marcucci, FE Baralle Nucleic acids research 29 (4), 886-894, 2001 | 41 | 2001 |
| Eosinophil peroxidase: Structure functions and perspectives G Zabucchi, V Borelli, MG PERROTTA, MR Soranzo, M MAGNARIN Recent research developments in allergy & clinical immunology, 17-44, 2001 | 1 | 2001 |
| Splicing factors induce cystic fibrosis transmembrane regulator exon 9 skipping through a nonevolutionary conserved intronic element F Pagani, E Buratti, C Stuani, M Romano, E Zuccato, M Niksic, L Giglio, ... Journal of Biological Chemistry 275 (28), 21041-21047, 2000 | 203 | 2000 |
| Functional characterization of the novel mutation IVS 8 (− 11delC)(− 14T> A) in the intron 8 of the glucocerebrosidase gene of two Italian siblings with Gaucher disease type I M Romano, GM Danek, FE Baralle, R Mazzotti, M Filocamo Blood Cells, Molecules, and Diseases 26 (3), 171-176, 2000 | 12 | 2000 |
| Expression and characterization of recombinant human eosinophil peroxidase: impact of the R286H substitution on the biosynthesis and activity of the enzyme M Romano, FE Baralle, P Patriarca European journal of biochemistry 267 (12), 3704-3711, 2000 | 10 | 2000 |
| Myeloperoxidase (MPO) and eosinophil peroxidase (EPO) deficiency in the region Friuli-Venezia Giulia of North-Eastern Italy P Patriarca, M Romano The Peroxidase Multigene Family of Enzymes, 122-128, 2000 | 1 | 2000 |
| Functional analysis of cis-acting elements regulating the alternative splicing of human CFTR exon 9 M Niksic, M Romano, E Buratti, F Pagani, FE Baralle Human molecular genetics 8 (13), 2339-2349, 1999 | 155 | 1999 |
| The A/G polymorphism in the− 78 position of the apolipoprotein AI promoter does not have a direct effect on transcriptional efficiency GM Danek, M Valenti, FE Baralle, M Romano Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1398 (1 …, 1998 | 23 | 1998 |
| Biochemical and molecular characterization of hereditary myeloperoxidase deficiency M Romano, P Dri, L Dadalt, P Patriarca, FE Baralle Blood, The Journal of the American Society of Hematology 90 (10), 4126-4134, 1997 | 61 | 1997 |
| Hereditary eosinophil peroxidase deficiency: immunochemical and spectroscopic studies and evidence for a compound heterozygosity of the defect M Romano, P Patriarca, C Melo, FE Baralle, P Dri Proceedings of the National Academy of Sciences 91 (26), 12496-12500, 1994 | 10 | 1994 |
| cDNA clones of myeloperoxidase (MPO) and eosinophil peroxidase (EPO) from human blood mononuclear cells differentiated into granulocyte precursors in liquid cultures. M Romano, C Melo, F Baralle, P Dri Journal of immunological methods 154 (2), 265-267, 1992 | 4 | 1992 |
| Eosinophil activation on biologic surfaces. Production of O2-in response to physiologic soluble stimuli is differentially modulated by extracellular matrix components and … P Dri, R Cramer, P Spessotto, M Romano, P Patriarca The Journal of Immunology 147 (2), 613-620, 1991 | 71 | 1991 |
| Effect of biological surfaces on neutrophil O2-production and its relationship to the CD11b/CD18 integrin-dependent adherence. P Dri, R Cramer, M Romano, P Spessotto, P Patriarca International journal of tissue reactions 13 (4), 193-201, 1991 | 39 | 1991 |
Emanuele BurattiICGEBVerified email at icgeb.org
