Maurizio Romano
Cited by
Changes in the Expression of COI1, TIR1, and ERF1 Genes and Respective MiRNAs in Fusarium Basal Rot-Stressed Onion
B Khansarinejad, F Dashti, E Buratti, A Mirzaie-Asl, D Zafari, M Romano
Gene, 148212, 2024
Age-Related Alternative Splicing: Driver or Passenger in the Aging Process?
M Baralle, M Romano
Cells 12 (24), 2819, 2023
Cytotoxicity Profiles and Neuroprotective Properties of the Novel Ifenprodil Analogues as Sigma Ligands
D Zampieri, A Calabretti, M Romano, S Fortuna, S Collina, E Amata, ...
Molecules 28 (8), 3431, 2023
Immediate stress dissipation in dual cross-link hydrogels controls osteogenic commitment of mesenchymal stem cells
C Pizzolitto, F Scognamiglio, P Sacco, S Lipari, M Romano, I Donati, ...
Carbohydrate Polymers 302, 120369, 2023
Synthesis, biological evaluation and computational studies of new hydrazide derivatives containing 1, 3, 4-oxadiazole as antitubercular agents
D Zampieri, S Fortuna, M Romano, A De Logu, G Cabiddu, A Sanna, ...
International Journal of Molecular Sciences 23 (23), 15295, 2022
NOS1AP is a novel molecular target and critical factor in TDP-43 pathology
S Cappelli, A Spalloni, F Feiguin, G Visani, U Šušnjar, AL Brown, ...
Brain Communications 4 (5), fcac242, 2022
Design, synthesis and biological evaluation of novel aminopropylcarboxamide derivatives as sigma ligands
D Zampieri, S Fortuna, M Romano, E Amata, M Dichiara, A Marrazzo, ...
Bioorganic & Medicinal Chemistry Letters 72, 128860, 2022
Unraveling the toxic effects mediated by the neurodegenerative disease–associated S375G mutation of TDP-43 and its S375E phosphomimetic variant
F Paron, S Barattucci, S Cappelli, M Romano, C Berlingieri, C Stuani, ...
Journal of Biological Chemistry 298 (8), 2022
Targets to watch in neuroinflammation: focus on RIPK1
M Romano
Drugs of the Future 47 (5), 347, 2022
Cell environment shapes TDP-43 function with implications in neuronal and muscle disease
U Šušnjar, N Škrabar, AL Brown, Y Abbassi, H Phatnani, A Cortese, ...
Communications biology 5 (1), 314, 2022
Physiological tissue-specific and age-related reduction of mouse TDP-43 levels is regulated by epigenetic modifications
M Pacetti, L De Conti, LE Marasco, M Romano, MM Rashid, M Nubič, ...
Disease Models & Mechanisms 15 (4), dmm049032, 2022
Identification of Parkinson's disease biomarkers through RNA sequencing of peripheral blood leukocytes
V Tommasini, M Catalan, M Romano, G Mazzon, T Cattaruzza, L Antonutti, ...
Journal of the Neurological Sciences 429, 2021
Characterization of the human TARDBP gene promoter
M Baralle, M Romano
Scientific Reports 11 (1), 10438, 2021
γ-and δ-lactones as fumarate esters analogues and their neuroprotective effects
F Cateni, P Nitti, S Drioli, G Procida, R Menegazzi, M Romano
Medicinal Chemistry Research 30, 913-924, 2021
Deferoxamine mesylate improves splicing and GAA activity of the common c.-32-13T> G allele in late-onset PD patient fibroblasts
E Buratti, P Peruzzo, L Braga, I Zanin, C Stuani, E Goina, M Romano, ...
Molecular Therapy-Methods & Clinical Development 20, 227-236, 2021
From basic research to the clinic: innovative therapies for ALS and FTD in the pipeline
RM Liscic, A Alberici, NJ Cairns, M Romano, E Buratti
Molecular Neurodegeneration 15 (1), 1-17, 2020
Synthesis, Cytotoxicity Evaluation and Computational Insights of Novel 1, 4-Diazepane-Based Sigma Ligands
D Zampieri, S Fortuna, A Calabretti, M Romano, R Menegazzi, ...
ACS Medicinal Chemistry Letters, 2019
Discovery of new potent dual sigma receptor/GluN2b ligands with antioxidant property as neuroprotective agents
D Zampieri, S Fortuna, A Calabretti, M Romano, R Menegazzi, ...
European Journal of Medicinal Chemistry 180, 268-282, 2019
Dysregulation of TDP‐43 intracellular localization and early onset ALS are associated with a TARDBP S375G variant
K Newell, F Paron, M Mompean, J Murrell, E Salis, C Stuani, G Pattee, ...
Brain Pathology 29 (3), 397-413, 2019
Early onset amyotrophic lateral sclerosis associated with a TARDBP S375G variant: neuropathologic characterization and neurobiologic studies
KL Newell, F Paron, J Murrell, E Salis, C Stuani, M Romano, B Ghetti, ...
BRAIN PATHOLOGY 29, 128-128, 2019
M Romano, FE Baralle
Giornale Italiano dell’Arteriosclerosi 10 (3), 5-14, 2019
New piperidine-based derivatives as sigma receptor ligands. Synthesis and pharmacological evaluation
D Zampieri, M Romano, R Menegazzi, MG Mamolo
Bioorganic & Medicinal Chemistry Letters 28 (19), 3206-3209, 2018
Systematic analysis of gene expression profiles controlled by hnRNP Q and hnRNP R, two closely related human RNA binding proteins implicated in mRNA processing mechanisms
S Cappelli, M Romano, E Buratti
Frontiers in Molecular Biosciences 5, 79, 2018
In silico/in vitro studies of novel hot spot mutations in BCR-ABL1: A multidisciplinary approach to shed a new light on TKI resistance
E Laurini, S Aulic, N Skoko, S Polez, M Baralle, M Romano, S Pricl
Cancer Research 78 (13_Supplement), 2382-2382, 2018
Essential role of hippocampal noradrenaline in the regulation of spatial working memory and TDP‐43 tissue pathology
R Pintus, M Riggi, C Cannarozzo, A Valeri, G de Leo, M Romano, ...
Journal of Comparative Neurology 526 (7), 1131-1147, 2018
RhoGAPp190: A potential player in tbph-mediated neurodegeneration in Drosophila
S Langellotti, G Romano, F Feiguin, FE Baralle, M Romano
Plos one 13 (4), e0195845, 2018
Role of the long non‐coding RNA growth arrest‐specific 5 in glucocorticoid response in children with inflammatory bowel disease
M Lucafň, A Di Silvestre, M Romano, A Avian, R Antonelli, S Martelossi, ...
Basic & clinical pharmacology & toxicology 122 (1), 87-93, 2018
Structural, Thermodynamics and Kinetics Role of Novel Hot-Spot Mutations of BCR-ABL1 in Resistance Towards
S Pricl, E Laurini, M Fermeglia, D Marson, S Aulic, M Romano, N Skoko, ...
2017 AIChE Annual Meeting, 2017
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells
C Appocher, F Mohagheghi, S Cappelli, C Stuani, M Romano, F Feiguin, ...
Nucleic acids research 45 (13), 8026-8045, 2017
Keratin14 mRNA expression in human pneumocytes during quiescence, repair and disease
M Confalonieri, E Buratti, G Grassi, R Bussani, M Chilosi, R Farra, ...
PLoS One 12 (2), e0172130, 2017
Computer-assisted design, synthesis, binding and cytotoxicity assessments of new 1-(4-(aryl (methyl) amino) butyl)-heterocyclic sigma 1 ligands
D Zampieri, L Vio, M Fermeglia, S Pricl, B Wünsch, D Schepmann, ...
European Journal of Medicinal Chemistry 121, 712-726, 2016
TBPH/TDP-43 modulates translation of Drosophila futsch mRNA through an UG-rich sequence within its 5′ UTR
M Romano, F Feiguin, E Buratti
Brain Research 1647, 50-56, 2016
Neuropathologic and neurobiologic characterization of early onset amyotrophic lateral sclerosis associated with a novel TDP43 S375G variant
K Newell, B Ghetti, J Murrell, M Romano, E Salis, C Stuani, E Buratti
Antimycobacterial activity of new N1-[1-[1-aryl-3-[4-(1H-imidazol-1-yl) phenyl]-3-oxo] propyl]-pyridine-2-carboxamidrazone derivatives
D Zampieri, MG Mamolo, L Vio, M Romano, N Skoko, M Baralle, V Pau, ...
Bioorganic & Medicinal Chemistry Letters 26 (14), 3287-3290, 2016
New neurogenic lipoic-based hybrids as innovative Alzheimer's drugs with σ-1 agonism and β-secretase inhibition
M Estrada, C Pérez, E Soriano, E Laurini, M Romano, S Pricl, ...
Future Medicinal Chemistry 8 (11), 1191-1207, 2016
A novel Drosophila model of TDP-43 proteinopathies: N-terminal sequences combined with the Q/N domain induce protein functional loss and locomotion defects
S Langellotti, V Romano, G Romano, R Klima, F Feiguin, L Cragnaz, ...
Disease Models & Mechanisms 9 (6), 659-669, 2016
Knockdown of MVK does not lead to changes in NALP3 expression or activation
F Celsi, E Piscianz, M Romano, S Crovella
Journal of Inflammation 12, 1-5, 2015
TDP-43 affects splicing profiles and isoform production of genes involved in the apoptotic and mitotic cellular pathways
L De Conti, MV Akinyi, R Mendoza-Maldonado, M Romano, M Baralle, ...
Nucleic acids research 43 (18), 8990-9005, 2015
Exome sequencing of a colorectal cancer family reveals shared mutation pattern and predisposition circuitry along tumor pathways
SH Suleiman, ME Koko, WH Nasir, O Elfateh, UK Elgizouli, MOE Abdallah, ...
Frontiers in genetics 6, 288, 2015
A novel anti-aldolase C antibody specifically interacts with residues 85–102 of the protein
S Langellotti, M Romano, C Guarnaccia, V Granata, S Orrů, A Zagari, ...
MAbs 6 (3), 707-716, 2014
Evolutionarily conserved heterogeneous nuclear ribonucleoprotein (hnRNP) A/B proteins functionally interact with human and Drosophila TAR DNA-binding protein 43 (TDP-43)
M Romano, E Buratti, G Romano, R Klima, LDB Belluz, C Stuani, ...
Journal of Biological Chemistry 289 (10), 7121-7130, 2014
Targeting RNA binding proteins involved in neurodegeneration
M Romano, E Buratti
Journal of biomolecular screening 18 (9), 967-983, 2013
Role of pseudoexons and pseudointrons in human cancer
M Romano, E Buratti, D Baralle
International journal of cell biology 2013, 2013
TDP-43 high throughput screening analyses in neurodegeneration: advantages and pitfalls
E Buratti, M Romano, FE Baralle
Molecular and Cellular Neuroscience 56, 465-474, 2013
Florbetapir F 18 for brain imaging of beta-amyloid plaques
M Romano, E Buratti
Drugs of Today 49 (3), 2013
Tirasemtiv (CK-2017357)
M Romano
Drugs of the Future 38 (3), 2013
Small Cytoplasmic Ribonucleoproteins
M Romano, E Buratti
Brenner's Encyclopedia of Genetics (Second Edition), 463-465, 2013
TDP-43 Regulates Drosophila Neuromuscular Junctions Growth by Modulating Synaptic Microtubules Organization
F Feiguin, G Romano, R Klima, M Romano, E Buratti, FE Baralle
Drosophila answers to TDP-43 proteinopathies. J Amino Acids 2012: 356081
M Romano, F Feiguin, E Buratti
Drosophila answers to TDP-43 proteinopathies
M Romano, F Feiguin, E Buratti
Journal of amino acids 2012, 2012
Splicing in the RNA World
E Buratti, M Romano, FE Baralle
Alternative pre‐mRNA Splicing, 3-12, 2012
TDP-43 regulates Drosophila neuromuscular junctions growth by modulating Futsch/MAP1B levels and synaptic microtubules organization
VK Godena, G Romano, M Romano, C Appocher, R Klima, E Buratti, ...
PloS one 6 (3), e17808, 2011
TDP-43 regulates its mRNA levels through a negative feedback loop
YM Ayala, S Laura De Conti, AD Vázquez, M Romano, A D'Ambrogio, ...
The EMBO journal 30 (2), 277-288, 2011
G runs in Cystathionine β-Synthase c. 833C/c. 844_845ins68 mRNA are splicing silencers of pathogenic 3′ splice sites
M Romano
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1799 (8), 568-574, 2010
Neuropeptides in saliva of subjects with burning mouth syndrome: a pilot study
V Borelli, A Marchioli, R Di Taranto, M Romano, S Chiandussi, ...
Oral diseases 16 (4), 365-374, 2010
Nuclear factor TDP‐43 can affect selected microRNA levels
E Buratti, L De Conti, C Stuani, M Romano, M Baralle, F Baralle
The FEBS journal 277 (10), 2268-2281, 2010
Functional mapping of the interaction between TDP-43 and hnRNP A2 in vivo
A D’Ambrogio, E Buratti, C Stuani, C Guarnaccia, M Romano, YM Ayala, ...
Nucleic acids research 37 (12), 4116-4126, 2009
Dissecting the splicing mechanism of the Drosophila editing enzyme; dADAR
R Marcucci, M Romano, F Feiguin, MA O'Connell, FE Baralle
Nucleic acids research 37 (5), 1663-1671, 2009
Thrombopoietin and its splicing variants: structure and functions in thrombopoiesis and beyond
R Marcucci, M Romano
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1782 (7-8 …, 2008
Origin and evolution of the c. 844_845ins68/c. 833T> C mutations within the cystathionine β-synthase gene in great apes
M Romano, MG Bacalini, EJ Verschoor, S Crovella, FE Baralle
FEBS letters 582 (3), 423-426, 2008
Aberrant 5′ splice sites in human disease genes: mutation pattern, nucleotide structure and comparison of computational tools that predict their utilization
E Buratti, M Chivers, J Královičová, M Romano, M Baralle, AR Krainer, ...
Nucleic acids research 35 (13), 4250-4263, 2007
Complex splicing control of the human Thrombopoietin gene by intronic G runs
R Marcucci, FE Baralle, M Romano
Nucleic acids research 35 (1), 132-142, 2007
Photodynamic therapy of subfoveal choroidal neovascularization secondary to reticular pattern dystrophy: three-year results of an uncontrolled, prospective case series
MB Parodi, T Liberali, M Pedio, PJ Francis, FC Piccolino, N Fiotti, ...
American journal of ophthalmology 141 (6), 1152-1154, 2006
Human, Drosophila, and C. elegans TDP43: nucleic acid binding properties and splicing regulatory function
YM Ayala, S Pantano, A D'Ambrogio, E Buratti, A Brindisi, C Marchetti, ...
Journal of molecular biology 348 (3), 575-588, 2005
Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene
PA Mercado, YM Ayala, M Romano, E Buratti, FE Baralle
Nucleic acids research 33 (18), 6000-6010, 2005
Genetic studies on myeloperoxidase deficiency in Italy
C Marchetti, P Patriarca, GP Solero, FE Baralle, M Romano
Jpn. J. Infect. Dis 57 (5), S10-2, 2004
An exonic splicing enhancer offsets the atypical GU-rich 3′ splice site of human apolipoprotein A-II exon 3
P Arrisi-Mercado, M Romano, AF Muro, FE Baralle
Journal of Biological Chemistry 279 (38), 39331-39339, 2004
Genetic characterization of myeloperoxidase deficiency in Italy
C Marchetti, P Patriarca, GP Solero, FE Baralle, M Romano
Human mutation 23 (5), 496-505, 2004
hnRNP H binding at the 5′ splice site correlates with the pathological effect of two intronic mutations in the NF-1 and TSHβ genes
E Buratti, M Baralle, L De Conti, D Baralle, M Romano, YM Ayala, ...
Nucleic acids research 32 (14), 4224-4236, 2004
Identification and subcellular localization of neuronal calcium sensor-1 (NCS-1) in human neutrophils and HL-60 cells
C Brochetta, MG Perrotta, A Jeromin, M Romano, F Vita, MR Soranzo, ...
Inflammation 27, 361-372, 2003
Regulation of 3′ splice site selection in the 844ins68 polymorphism of the cystathionine β-synthase gene
M Romano, R Marcucci, E Buratti, YM Ayala, G Sebastio, FE Baralle
Journal of Biological Chemistry 277 (46), 43821-43829, 2002
Genetic heterogeneity in malattia leventinese
L Toto, MB Parodi, F Baralle, G Casari, G Ravalico, M Romano
Clinical genetics 62 (5), 399-403, 2002
Glycolipid analysis of different tissues and cerebrospinal fluid in type II Gaucher disease
R Gornati, B Berra, G Montorfano, C Martini, G Ciana, P Ferrari, ...
Journal of inherited metabolic disease 25 (1), 47-55, 2002
Minor role for BRCA2 (exon11) and p53 (exon 5–9) among Sudanese breast cancer patients
MA Masri, NM Abdel Seed, AH Fahal, M Romano, F Baralle, ...
Breast cancer research and treatment 71, 145-147, 2002
Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping
E Buratti, T Dörk, E Zuccato, F Pagani, M Romano, FE Baralle
The EMBO journal 20 (7), 1774-1784, 2001
Splicing of constitutive upstream introns is essential for the recognition of intra-exonic suboptimal splice sites in the thrombopoietin gene
M Romano, R Marcucci, FE Baralle
Nucleic acids research 29 (4), 886-894, 2001
Eosinophil peroxidase: Structure functions and perspectives
G Zabucchi, V Borelli, MG PERROTTA, MR Soranzo, M MAGNARIN, ...
Recent research developments in allergy & clinical immunology, 17-44, 2001
Splicing factors induce cystic fibrosis transmembrane regulator exon 9 skipping through a nonevolutionary conserved intronic element
F Pagani, E Buratti, C Stuani, M Romano, E Zuccato, M Niksic, L Giglio, ...
Journal of Biological Chemistry 275 (28), 21041-21047, 2000
Functional characterization of the novel mutation IVS 8 (− 11delC)(− 14T> A) in the intron 8 of the glucocerebrosidase gene of two Italian siblings with Gaucher disease type I
M Romano, GM Danek, FE Baralle, R Mazzotti, M Filocamo
Blood Cells, Molecules, and Diseases 26 (3), 171-176, 2000
Expression and characterization of recombinant human eosinophil peroxidase: Impact of the R286H substitution on the biosynthesis and activity of the enzyme
M Romano, FE Baralle, P Patriarca
European Journal of Biochemistry 267 (12), 3704-3711, 2000
Splicing factors induce cystic transmembrane regulator exon 9 skipping through a nonevolutionary conserved intronic element
F Pagani, E Buratti, C Stuani, M Romano, E Zuccato, M Niksic, L Giglio, ...
J. Biol. Chem 275, 210141-210147, 2000
Myeloperoxidase (MPO) and eosinophil peroxidase (EPO) deficiency in the region Friuli-Venezia Giulia of North-Eastern Italy
P Patriarca, M Romano
The Peroxidase Multigene Family of Enzymes: Biochemical Basis and Clinical …, 2000
Functional analysis of cis-acting elements regulating the alternative splicing of human CFTR exon 9
M Niksic, M Romano, E Buratti, F Pagani, FE Baralle
Human molecular genetics 8 (13), 2339-2349, 1999
The A/G polymorphism in the− 78 position of the apolipoprotein AI promoter does not have a direct effect on transcriptional efficiency
GM Danek, M Valenti, FE Baralle, M Romano
Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1398 (1 …, 1998
Biochemical and molecular characterization of hereditary myeloperoxidase deficiency
M Romano, P Dri, L Dadalt, P Patriarca, FE Baralle
Blood, The Journal of the American Society of Hematology 90 (10), 4126-4134, 1997
Hereditary eosinophil peroxidase deficiency: immunochemical and spectroscopic studies and evidence for a compound heterozygosity of the defect.
M Romano, P Patriarca, C Melo, FE Baralle, P Dri
Proceedings of the National Academy of Sciences 91 (26), 12496-12500, 1994
cDNA clones of myeloperoxidase (MPO) and eosinophil peroxidase (EPO) from human blood mononuclear cells differentiated into granulocyte precursors in liquid cultures.
M Romano, C Melo, F Baralle, P Dri
Journal of immunological methods 154 (2), 265-267, 1992
Eosinophil activation on biologic surfaces. Production of O2-in response to physiologic soluble stimuli is differentially modulated by extracellular matrix components and …
P Dri, R Cramer, P Spessotto, M Romano, P Patriarca
Journal of Immunology (Baltimore, Md.: 1950) 147 (2), 613-620, 1991
Effect of biological surfaces on neutrophil O2-production and its relationship to the CD11b/CD18 integrin-dependent adherence.
P Dri, R Cramer, M Romano, P Spessotto, P Patriarca
International journal of tissue reactions 13 (4), 193-201, 1991
Structure of RNA, RNA World, role of splicing and alternative splicing history.
E Buratti, M Romano, FE Baralle
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Articles 1–90