Marco Pirazzini
Citata da
Citata da
Botulinum neurotoxins: genetic, structural and mechanistic insights
O Rossetto, M Pirazzini, C Montecucco
Nature Reviews Microbiology 12 (8), 535-549, 2014
Botulinum neurotoxins: biology, pharmacology, and toxicology
M Pirazzini, O Rossetto, R Eleopra, C Montecucco
Pharmacological reviews 69 (2), 200-235, 2017
Historical perspectives and guidelines for botulinum neurotoxin subtype nomenclature
MW Peck, TJ Smith, F Anniballi, JW Austin, L Bano, M Bradshaw, ...
Toxins 9 (1), 38, 2017
Thioredoxin and its reductase are present on synaptic vesicles, and their inhibition prevents the paralysis induced by botulinum neurotoxins
M Pirazzini, G Zanetti, A Megighian, M Scorzeto, S Fillo, CC Shone, T Binz, ...
Cell Reports 8 (6), 1870-1878, 2014
Double anchorage to the membrane and intact inter‐chain disulfide bond are required for the low pH induced entry of tetanus and botulinum neurotoxins into neurons
M Pirazzini, O Rossetto, P Bolognese, CC Shone, C Montecucco
Cellular microbiology 13 (11), 1731-1743, 2011
On the translocation of botulinum and tetanus neurotoxins across the membrane of acidic intracellular compartments
M Pirazzini, O Leka, G Zanetti, O Rossetto, C Montecucco
Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (3), 467-474, 2016
Botulinum neurotoxin type A is internalized and translocated from small synaptic vesicles at the neuromuscular junction
C Colasante, O Rossetto, L Morbiato, M Pirazzini, J Molgˇ, C Montecucco
Molecular neurobiology 48 (1), 120-127, 2013
The thioredoxin reductase-thioredoxin system is involved in the entry of tetanus and botulinum neurotoxins in the cytosol of nerve terminals
M Pirazzini, F Bordin, O Rossetto, CC Shone, T Binz, C Montecucco
FEBS letters 587 (2), 150-155, 2013
Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain
M Pirazzini, T Henke, O Rossetto, S Mahrhold, N Krez, A Rummel, ...
FEBS letters 587 (23), 3831-3836, 2013
Botulinum neurotoxin serotype D is poorly effective in humans: an in vivo electrophysiological study
R Eleopra, C Montecucco, G Devigili, C Lettieri, S Rinaldo, L Verriello, ...
Clinical Neurophysiology 124 (5), 999-1004, 2013
Hsp90 is involved in the entry of clostridial neurotoxins into the cytosol of nerve terminals
D Azarnia Tehran, M Pirazzini, O Leka, A Mattarei, F Lista, T Binz, ...
Cellular Microbiology 19 (2), e12647, 2017
The thioredoxin reductase–Thioredoxin redox system cleaves the interchain disulphide bond of botulinum neurotoxins on the cytosolic surface of synaptic vesicles
M Pirazzini, G Zanetti, F Lista, T Binz, CC Shone, O Rossetto, ...
Toxicon 107, 32-36, 2015
Time course and temperature dependence of the membrane translocation of tetanus and botulinum neurotoxins C and D in neurons
M Pirazzini, O Rossetto, C Bertasio, F Bordin, CC Shone, T Binz, ...
Biochemical and biophysical research communications 430 (1), 38-42, 2013
Novel botulinum neurotoxins: Exploring underneath the iceberg tip
M Pirazzini
Toxins 10 (5), 190, 2018
Diphtheria toxin conformational switching at acidic pH
O Leka, F Vallese, M Pirazzini, P Berto, C Montecucco, G Zanotti
The FEBS journal 281 (9), 2115-2122, 2014
Inhibition of botulinum neurotoxins interchain disulfide bond reduction prevents the peripheral neuroparalysis of botulism
G Zanetti, M Pirazzini, T Binz, CC Shone, S Fillo, F Lista, O Rossetto, ...
Biochemical pharmacology 98 (3), 522-530, 2015
Re-assembled botulinum neurotoxin inhibits CNS functions without systemic toxicity
E Ferrari, ES Maywood, L Restani, M Caleo, M Pirazzini, O Rossetto, ...
Toxins 3 (4), 345-355, 2011
Challenges in searching for therapeutics against botulinum neurotoxins
M Pirazzini, O Rossetto
Expert opinion on drug discovery 12 (5), 497-510, 2017
A novel inhibitor prevents the peripheral neuroparalysis of botulinum neurotoxins
G Zanetti, O Leka, F Lista, S Fillo, T Binz, CC Shone, O Rossetto, ...
Scientific reports 5, 17513, 2015
Postnatal development and distribution of sympathetic innervation in mouse skeletal muscle
T Straka, V Vita, K Prokshi, SJ H÷rner, MM Khan, M Pirazzini, ...
International journal of molecular sciences 19 (7), 1935, 2018
Il sistema al momento non pu˛ eseguire l'operazione. Riprova pi¨ tardi.
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