Luca Orlando, PhD
Luca Orlando, PhD
Blue Rock Therapeutics
Email verificata su - Home page
Citata da
Citata da
High basal γH2AX levels sustain self-renewal of mouse embryonic and induced pluripotent stem cells
V Turinetto, L Orlando, Y Sanchez-Ripoll, B Kumpfmueller, MP Storm, ...
stem cells 30 (7), 1414-1423, 2012
A rapid flow cytometry test based on histone H2AX phosphorylation for the sensitive and specific diagnosis of ataxia telangiectasia
P Porcedda, V Turinetto, A Brusco, S Cavalieri, E Lantelme, L Orlando, ...
Cytometry Part A: The Journal of the International Society for Analytical …, 2008
Induced pluripotent stem cells: advances in the quest for genetic stability during reprogramming process
V Turinetto, L Orlando, C Giachino
International journal of molecular sciences 18 (9), 1952, 2017
Fluorescent Silica Nanoparticles Improve Optical Imaging of Stem Cells Allowing Direct Discrimination between Live and Early‐Stage Apoptotic Cells
L Accomasso, EC Rocchietti, S Raimondo, F Catalano, G Alberto, ...
Small 8 (20), 3192-200, 2012
Sam68 allows selective targeting of human cancer stem cells
YD Benoit, RR Mitchell, RM Risueño, L Orlando, B Tanasijevic, AL Boyd, ...
Cell Chemical Biology 24 (7), 833-844. e9, 2017
Human pluripotency is initiated and preserved by a unique subset of founder cells
M Nakanishi, RR Mitchell, YD Benoit, L Orlando, JC Reid, K Shimada, ...
Cell 177 (4), 910-924. e22, 2019
Brief report: human acute myeloid leukemia reprogramming to pluripotency is a rare event and selects for patient hematopoietic cells devoid of leukemic mutations
JH Lee, KR Salci, JC Reid, L Orlando, B Tanasijevic, Z Shapovalova, ...
Stem Cells 35 (9), 2095-2102, 2017
Maintenance of genomic stability in mouse embryonic stem cells: relevance in aging and disease
C Giachino, L Orlando, V Turinetto
International Journal of Molecular Sciences 14 (2), 2617-2636, 2013
Two-tier analysis of histone H2AX phosphorylation allows the identification of Ataxia Telangiectasia heterozygotes
P Porcedda, V Turinetto, L Orlando, E Lantelme, A Brusco, M De Marchi, ...
Radiotherapy and Oncology 92 (1), 133-137, 2009
An in vitro model of T cell receptor revision in mature human CD8+ T cells
E Lantelme, L Orlando, P Porcedda, V Turinetto, M De Marchi, A Amoroso, ...
Molecular immunology 45 (2), 328-337, 2008
The cyclin-dependent kinase inhibitor 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole induces nongenotoxic, DNA replication-independent apoptosis of normal and leukemic cells …
V Turinetto, P Porcedda, L Orlando, M De Marchi, A Amoroso, C Giachino
BMC cancer 9 (1), 1-13, 2009
Expression of IFNγR2 mutated in a dileucine internalization motif reinstates IFNγ signaling and apoptosis in human T lymphocytes
D Boselli, J Ragimbeau, L Orlando, P Cappello, M Capello, C Ambrogio, ...
Immunology letters 134 (1), 17-25, 2010
Involvement of MRE11A and XPA gene polymorphisms in the modulation of DNA double-strand break repair activity: A genotype–phenotype correlation study
F Ricceri, P Porcedda, A Allione, V Turinetto, S Polidoro, S Guarrera, ...
DNA repair 10 (10), 1044-1050, 2011
Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics
YD Benoit, RR Mitchell, W Wang, L Orlando, AL Boyd, B Tanasijevic, ...
Cell Chemical Biology 28 (10), 1394-1406. e10, 2021
Differential coupling of self-renewal signaling pathways in murine induced pluripotent stem cells
L Orlando, Y Sanchez-Ripoll, J Foster, H Bone, C Giachino, MJ Welham
PLoS One 7 (1), e30234, 2012
A novel defect in mitochondrial p53 accumulation following DNA damage confers apoptosis resistance in Ataxia Telangiectasia and Nijmegen Breakage Syndrome T-cells
V Turinetto, P Porcedda, V Minieri, L Orlando, E Lantelme, L Accomasso, ...
DNA repair 9 (11), 1200-1208, 2010
Phosphorylation state of the histone variant H2A. X controls human stem and progenitor cell fate decisions
L Orlando, B Tanasijevic, M Nakanishi, JC Reid, JL García-Rodríguez, ...
Cell Reports 34 (10), 2021
Acquisition of pluripotency through continued environmental influence on OCT4-induced plastic human fibroblasts
KR Salci, JB Lee, RR Mitchell, L Orlando, A Fiebig-Comyn, ...
Stem Cell Research 15 (1), 221-230, 2015
TCR transfer induces TCR-mediated tonic inhibition of RAG genes in human T cells
L Orlando, L Accomasso, P Circosta, V Turinetto, E Lantelme, P Porcedda, ...
Molecular Immunology 48 (12-13), 1369-76, 2011
Human pluripotent stem cells identify molecular targets of trisomy 12 in chronic lymphocytic leukemia patients
JC Reid, D Golubeva, AL Boyd, CG Hollands, C Henly, L Orlando, ...
Cell Reports 34 (11), 2021
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