Roberto Nitsch
Roberto Nitsch
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The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells
M Paolino, A Choidas, S Wallner, B Pranjic, I Uribesalgo, S Loeser, ...
Nature 507 (7493), 508-512, 2014
A dual role for autophagy in a murine model of lung cancer.
Nat Commun 2014 5 (3056), 2014
In vivo CRISPR editing with no detectable genome-wide off-target mutations
P Akcakaya, ML Bobbin, JA Guo, J Malagon-Lopez, K Clement, SP Garcia, ...
Nature 561 (7723), 416-419, 2018
The paired domain-containing factor Pax8 and the homeodomain-containing factor TTF-1 directly interact and synergistically activate transcription
T Di Palma, R Nitsch, A Mascia, L Nitsch, R Di Lauro, M Zannini
Journal of Biological Chemistry 278 (5), 3395-3402, 2003
Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes
M Daugaard, R Nitsch, B Razaghi, L McDonald, A Jarrar, S Torrino, ...
Nature communications 4 (1), 1-13, 2013
HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response
B Rotblat, AL Southwell, DE Ehrnhoefer, NH Skotte, M Metzler, ...
Proceedings of the National Academy of Sciences 111 (8), 3032-3037, 2014
CRISPR-UMI: single-cell lineage tracing of pooled CRISPR–Cas9 screens
G Michlits, M Hubmann, SH Wu, G Vainorius, E Budusan, S Zhuk, ...
Nature methods 14 (12), 1191-1197, 2017
Decoding non-random mutational signatures at Cas9 targeted sites
A Taheri-Ghahfarokhi, BJM Taylor, R Nitsch, A Lundin, AL Cavallo, ...
Nucleic acids research 46 (16), 8417-8434, 2018
The tumor suppressor Hace1 is a critical regulator of TNFR1-mediated cell fate
L Tortola, R Nitsch, MJM Bertrand, M Kogler, Y Redouane, I Kozieradzki, ...
Cell reports 15 (7), 1481-1492, 2016
In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model
A Carreras, LS Pane, R Nitsch, K Madeyski-Bengtson, M Porritt, ...
BMC biology 17 (1), 1-14, 2019
CDH16/Ksp-cadherin is expressed in the developing thyroid gland and is strongly down-regulated in thyroid carcinomas
G Cal, F Gentile, S Mogavero, P Pallante, R Nitsch, G Ciancia, A Ferraro, ...
Endocrinology 153 (1), 522-534, 2012
Pendrin is a novel in vivo downstream target gene of the TTF-1/Nkx-2.1 homeodomain transcription factor in differentiated thyroid cells
M Dentice, C Luongo, A Elefante, R Ambrosio, S Salzano, M Zannini, ...
Molecular and cellular biology 25 (22), 10171-10182, 2005
Therapeutic genome editing with CRISPR/Cas9 in a humanized mouse model ameliorates α1-antitrypsin deficiency phenotype
M Bjursell, MJ Porritt, E Ericson, A Taheri-Ghahfarokhi, M Clausen, ...
EBioMedicine 29, 104-111, 2018
WBP-2, a WW domain binding protein, interacts with the thyroid-specific transcription factor Pax8
R Nitsch, T Di Palma, A Mascia, M Zannini
Biochemical Journal 377 (3), 553-560, 2004
Comparative genomics reveals a functional thyroid-specific element in the far upstream region of the PAX8 gene
R Nitsch, V Di Dato, A di Gennaro, T de Cristofaro, S Abbondante, ...
BMC genomics 11 (1), 1-13, 2010
Functional inactivation of the transcription factor Pax8 through oligomerization chain reaction
B D’Andrea, R Iacone, T Di Palma, R Nitsch, MG Baratta, L Nitsch, ...
Molecular Endocrinology 20 (8), 1810-1824, 2006
RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer
S Rao, V Sigl, RA Wimmer, M Novatchkova, A Jais, G Wagner, ...
Genes & development 31 (20), 2099-2112, 2017
HACE1 deficiency leads to structural and functional neurodevelopmental defects
V Nagy, R Hollstein, TP Pai, MK Herde, P Buphamalai, P Moeseneder, ...
Neurology Genetics 5 (3), 2019
Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery
A Lundin, MJ Porritt, H Jaiswal, F Seeliger, C Johansson, AW Bidar, ...
Nature communications 11 (1), 1-16, 2020
HACE1 prevents lung carcinogenesis via inhibition of RAC-family GTPases
M Kogler, L Tortola, GL Negri, A Leopoldi, AM El-Naggar, S Mereiter, ...
Cancer research 80 (14), 3009-3022, 2020
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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