Meli Massimiliano
Meli Massimiliano
Istituto di Scienze e Tecnologie Chimiche (SCITEC-CNR)
Verified email at scitec.cnr.it - Homepage
Title
Cited by
Cited by
Year
Rational design of shepherdin, a novel anticancer agent
J Plescia, W Salz, F Xia, M Pennati, N Zaffaroni, MG Daidone, M Meli, ...
Cancer cell 7 (5), 457-468, 2005
3802005
Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90
BH Kang, J Plescia, HY Song, M Meli, G Colombo, K Beebe, B Scroggins, ...
The Journal of clinical investigation 119 (3), 454-464, 2009
1992009
Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors
B Gyurkocza, J Plescia, CM Raskett, DS Garlick, PA Lowry, BZ Carter, ...
Journal of the National Cancer Institute 98 (15), 1068-1077, 2006
1062006
Small-molecule targeting of heat shock protein 90 chaperone function: rational identification of a new anticancer lead
M Meli, M Pennati, M Curto, MG Daidone, J Plescia, S Toba, DC Altieri, ...
Journal of medicinal chemistry 49 (26), 7721-7730, 2006
1052006
Pharmacological enhancement of α-glucosidase by the allosteric chaperone N-acetylcysteine
C Porto, MC Ferrara, M Meli, E Acampora, V Avolio, M Rosa, ...
Molecular Therapy 20 (12), 2201-2211, 2012
842012
A multiscale approach to characterize the early aggregation steps of the amyloid-forming peptide GNNQQNY from the yeast prion sup-35
J Nasica-Labouze, M Meli, P Derreumaux, G Colombo, N Mousseau
PLoS Comput Biol 7 (5), e1002051, 2011
762011
Dynamic diagnosis of familial prion diseases supports the β2-α2 loop as a universal interference target
M Meli, M Gasset, G Colombo
PloS one 6 (4), e19093, 2011
762011
Synthesis, Structure and Conformation of Partially-Modified Retro-and Retro-Inverso Ψ [NHCH (CF~ 3)] Gly Peptides
A Volonterio, S Bellosta, F Bravin, MC Bellucci, L Bruché, G Colombo, ...
CHEMISTRY-WEINHEIM-EUROPEAN JOURNAL- 9 (18), 4510-4522, 2003
732003
Understanding ligand-based modulation of the Hsp90 molecular chaperone dynamics at atomic resolution
G Colombo, G Morra, M Meli, G Verkhivker
Proceedings of the National Academy of Sciences 105 (23), 7976-7981, 2008
712008
Methionine sulfoxides on prion protein helix-3 switch on the α-fold destabilization required for conversion
G Colombo, M Meli, G Morra, R Gabizon, M Gasset
PloS one 4 (1), e4296, 2009
582009
Effects of water miscible organic solvents on the activity and conformation of the Baeyer–Villiger monooxygenases from Thermobifida fusca and Acinetobacter calcoaceticus: a …
F Secundo, S Fiala, MW Fraaije, G de Gonzalo, M Meli, F Zambianchi, ...
Biotechnology and bioengineering 108 (3), 491-499, 2011
532011
Investigating the mechanism of peptide aggregation: insights from mixed Monte Carlo-molecular dynamics simulations
M Meli, G Morra, G Colombo
Biophysical journal 94 (11), 4414-4426, 2008
512008
Structure elucidation and 3D solution conformation of the antibiotic enduracidin determined by NMR spectroscopy and molecular dynamics
F Castiglione, A Marazzi, M Meli, G Colombo
Magnetic Resonance in Chemistry 43 (8), 603-610, 2005
332005
Cañada, J.; Asensio, JL; Jiménez-Barberob, J. Toward the understanding of the structure and dynamics of protein–carbohydrate interactions: molecular dynamics studies of the …
G Colombo, M Meli
Carbohydr. Res 339, 985-994, 2004
292004
Molecular dynamics simulations of proteins and peptides: from folding to drug design
G Morra, M Meli, G Colombo
Current Protein and Peptide Science 9 (2), 181-196, 2008
272008
The five-to-six-coordination transition of ferric human serum heme-albumin is allosterically-modulated by ibuprofen and warfarin: A combined XAS and MD study
C Meneghini, L Leboffe, M Bionducci, G Fanali, M Meli, G Colombo, ...
PLoS One 9 (8), e104231, 2014
232014
Crystal structure of the DFNKF segment of human calcitonin unveils aromatic interactions between phenylalanines
A Bertolani, A Pizzi, L Pirrie, L Gazzera, G Morra, M Meli, G Colombo, ...
Chemistry (Weinheim an der Bergstrasse, Germany) 23 (9), 2051, 2017
222017
The structural intolerance of the PrP α-fold for polar substitution of the helix-3 methionines
S Lisa, M Meli, G Cabello, R Gabizon, G Colombo, M Gasset
Cellular and molecular life sciences 67 (16), 2825-2838, 2010
222010
A Hamiltonian replica exchange molecular dynamics (MD) method for the study of folding, based on the analysis of the stabilization determinants of proteins
M Meli, G Colombo
International journal of molecular sciences 14 (6), 12157-12169, 2013
182013
Computational studies of the structure, dynamics and native content of amyloid‐like fibrils of ribonuclease A
G Colombo, M Meli, A De Simone
Proteins: Structure, Function, and Bioinformatics 70 (3), 863-872, 2008
182008
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Articles 1–20