Segui
Nathaniel A. Hathaway
Nathaniel A. Hathaway
Associate Professor, the UNC Eshelman School of Pharmacy, Chemical Biology and Medicinal Chemistry
Email verificata su unc.edu - Home page
Titolo
Citata da
Citata da
Anno
Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology
DS Kirkpatrick, NA Hathaway, J Hanna, S Elsasser, J Rush, D Finley, ...
Nature cell biology 8 (7), 700-710, 2006
5132006
Dynamics and memory of heterochromatin in living cells
NA Hathaway, O Bell, C Hodges, EL Miller, DS Neel, GR Crabtree
Cell 149 (7), 1447-1460, 2012
4792012
Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation
N Bardeesy, M Sinha, AF Hezel, S Signoretti, NA Hathaway, ...
Nature 419 (6903), 162-167, 2002
4792002
Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation
J Hanna, NA Hathaway, Y Tone, B Crosas, S Elsasser, DS Kirkpatrick, ...
Cell 127 (1), 99-111, 2006
4282006
Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities
B Crosas, J Hanna, DS Kirkpatrick, DP Zhang, Y Tone, NA Hathaway, ...
Cell 127 (7), 1401-1413, 2006
3672006
Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage
X Zeng, F Sigoillot, S Gaur, S Choi, KL Pfaff, DC Oh, N Hathaway, ...
Cancer cell 18 (4), 382-395, 2010
3362010
APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1
NV Dimova, NA Hathaway, BH Lee, DS Kirkpatrick, ML Berkowitz, ...
Nature cell biology 14 (2), 168-176, 2012
1722012
Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites
MF Kleijnen, J Roelofs, S Park, NA Hathaway, M Glickman, RW King, ...
Nature structural & molecular biology 14 (12), 1180-1188, 2007
1632007
Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma
BE Gryder, S Pomella, C Sayers, XS Wu, Y Song, AM Chiarella, S Bagchi, ...
Nature genetics 51 (12), 1714-1722, 2019
1242019
Nucleosome turnover regulates histone methylation patterns over the genome
EJ Chory, JP Calarco, NA Hathaway, O Bell, DS Neel, GR Crabtree
Molecular cell 73 (1), 61-72. e3, 2019
872019
Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding
A Skrajna, D Goldfarb, KM Kedziora, EM Cousins, GD Grant, CJ Spangler, ...
Nucleic acids research 48 (17), 9415-9432, 2020
692020
Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery
AM Chiarella, KV Butler, BE Gryder, D Lu, TA Wang, X Yu, S Pomella, ...
Nature biotechnology 38 (1), 50-55, 2020
612020
LSH mediates gene repression through macroH2A deposition
K Ni, J Ren, X Xu, Y He, R Finney, SMG Braun, NA Hathaway, ...
Nature communications 11 (1), 5647, 2020
352020
Epigenetic control of a local chromatin landscape
AM Chiarella, D Lu, NA Hathaway
International journal of molecular sciences 21 (3), 943, 2020
272020
Deferiprone: pan-selective histone lysine demethylase inhibition activity and structure activity relationship study
V Khodaverdian, S Tapadar, IA MacDonald, Y Xu, PY Ho, A Bridges, ...
Scientific reports 9 (1), 4802, 2019
272019
Ring finger protein 121 is a potent regulator of adeno-associated viral genome transcription
VJ Madigan, JA Yuziuk, AM Chiarella, TO Tyson, RM Meganck, ...
PLoS pathogens 15 (8), e1007988, 2019
252019
Targeted gene repression using novel bifunctional molecules to harness endogenous histone deacetylation activity
KV Butler, AM Chiarella, J Jin, NA Hathaway
ACS synthetic biology 7 (1), 38-45, 2018
252018
Design, implementation, and outcomes of a three-week pharmacy bridging course
JE McLaughlin, J Khanova, A Persky, N Hathaway, W Cox
American Journal of Pharmaceutical Education 81 (7), 6313, 2017
252017
Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks
W Feng, DA Simpson, JE Cho, J Carvajal-Garcia, CM Smith, KM Headley, ...
Nucleic Acids Research 49 (9), 5095-5105, 2021
172021
Tethering of Lsh at the Oct4 locus promotes gene repression associated with epigenetic changes
J Ren, NA Hathaway, GR Crabtree, K Muegge
Epigenetics 13 (2), 173-181, 2018
152018
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
Articoli 1–20