Johnathan Cooper-Knock
Johnathan Cooper-Knock
Clinical Fellow, University of Sheffield
Email verificata su sheffield.ac.uk
Titolo
Citata da
Citata da
Anno
Clinico-pathological features in amyotrophic lateral sclerosis with expansions in C9ORF72
J Cooper-Knock, C Hewitt, JR Highley, A Brockington, A Milano, S Man, ...
Brain 135 (3), 751-764, 2012
2772012
Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions
J Cooper-Knock, MJ Walsh, A Higginbottom, J Robin Highley, ...
Brain 137 (7), 2040-2051, 2014
2062014
Gene expression profiling in human neurodegenerative disease
J Cooper-Knock, J Kirby, L Ferraiuolo, PR Heath, M Rattray, PJ Shaw
Nature Reviews Neurology 8 (9), 518-530, 2012
1762012
Genome-wide analyses identify KIF5A as a novel ALS gene
A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ...
Neuron 97 (6), 1268-1283. e6, 2018
1562018
The widening spectrum of C9ORF72-related disease; genotype/phenotype correlations and potential modifiers of clinical phenotype
J Cooper-Knock, PJ Shaw, J Kirby
Acta neuropathologica 127 (3), 333-345, 2014
1462014
Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy
J Cooper-Knock, A Higginbottom, MJ Stopford, JR Highley, PG Ince, ...
Acta neuropathologica 130 (1), 63-75, 2015
1042015
TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions
MD Gallagher, E Suh, M Grossman, L Elman, L McCluskey, ...
Acta neuropathologica 127 (3), 407-418, 2014
942014
C9ORF72 GGGGCC expanded repeats produce splicing dysregulation which correlates with disease severity in amyotrophic lateral sclerosis
J Cooper-Knock, JJ Bury, PR Heath, M Wyles, A Higginbottom, ...
PloS one 10 (5), e0127376, 2015
882015
Loss of nuclear TDP‐43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones
JR Highley, J Kirby, JA Jansweijer, PS Webb, CA Hewamadduma, ...
Neuropathology and applied neurobiology 40 (6), 670-685, 2014
642014
Serum miRNAs miR-206, 143-3p and 374b-5p as potential biomarkers for amyotrophic lateral sclerosis (ALS)
R Waller, EF Goodall, M Milo, J Cooper-Knock, M Da Costa, E Hobson, ...
Neurobiology of aging 55, 123-131, 2017
562017
Concurrence of multiple sclerosis and amyotrophic lateral sclerosis in patients with hexanucleotide repeat expansions of C9ORF72
A Ismail, J Cooper-Knock, JR Highley, A Milano, J Kirby, E Goodall, ...
Journal of Neurology, Neurosurgery & Psychiatry 84 (1), 79-87, 2013
542013
Simultaneous and independent detection of C9ORF72 alleles with low and high number of GGGGCC repeats using an optimised protocol of Southern blot hybridisation
VL Buchman, J Cooper-Knock, N Connor-Robson, A Higginbottom, ...
Molecular neurodegeneration 8 (1), 12, 2013
512013
C9ORF72 expansions, parkinsonism, and Parkinson disease: a clinicopathologic study
J Cooper-Knock, A Frolov, JR Highley, G Charlesworth, J Kirby, A Milano, ...
Neurology 81 (9), 808-811, 2013
512013
SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits
GM Hautbergue, LM Castelli, L Ferraiuolo, A Sanchez-Martinez, ...
Nature communications 8, 16063, 2017
502017
The spectrum of C9orf72-mediated neurodegeneration and amyotrophic lateral sclerosis
J Cooper-Knock, J Kirby, R Highley, PJ Shaw
Neurotherapeutics 12 (2), 326-339, 2015
502015
Invited review: decoding the pathophysiological mechanisms that underlie RNA dysregulation in neurodegenerative disorders: a review of the current state of the art
MJ Walsh, J Cooper‐Knock, JE Dodd, MJ Stopford, SR Mihaylov, J Kirby, ...
Neuropathology and Applied Neurobiology 41 (2), 109-134, 2015
482015
How well do we recognise non-motor symptoms in a British Parkinson’s disease population?
M Hu, J Cooper, R Beamish, E Jones, R Butterworth, L Catterall, ...
Journal of neurology 258 (8), 1513-1517, 2011
402011
Oligogenic inheritance of optineurin (OPTN) and C9ORF72 mutations in ALS highlights localisation of OPTN in the TDP‐43‐negative inclusions of C9ORF72‐ALS
JJ Bury, JR Highley, J Cooper‐Knock, EF Goodall, A Higginbottom, ...
Neuropathology 36 (2), 125-134, 2016
352016
C9ORF72 transcription in a frontotemporal dementia case with two expanded alleles
J Cooper-Knock, A Higginbottom, N Connor-Robson, N Bayatti, JJ Bury, ...
Neurology 81 (19), 1719-1721, 2013
332013
Comparison of blood RNA extraction methods used for gene expression profiling in amyotrophic lateral sclerosis
N Bayatti, J Cooper-Knock, JJ Bury, M Wyles, PR Heath, J Kirby, PJ Shaw
PloS one 9 (1), e87508, 2014
322014
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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