| Glucose metabolism in the progression of prostate cancer F Cutruzzola, G Giardina, M Marani, A Macone, A Paiardini, S Rinaldo, ... Frontiers in physiology 8, 97, 2017 | 141 | 2017 |
| Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases G Giardina, R Montioli, S Gianni, B Cellini, A Paiardini, CB Voltattorni, ... Proceedings of the National Academy of sciences 108 (51), 20514-20519, 2011 | 119 | 2011 |
| SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation A Paone, M Marani, A Fiascarelli, S Rinaldo, G Giardina, R Contestabile, ... Cell death & disease 5 (11), e1525-e1525, 2014 | 118 | 2014 |
| NO sensing in Pseudomonas aeruginosa: structure of the transcriptional regulator DNR G Giardina, S Rinaldo, KA Johnson, A Di Matteo, M Brunori, F Cutruzzolà Journal of molecular biology 378 (5), 1002-1015, 2008 | 107 | 2008 |
| How pyridoxal 5’-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state G Giardina, P Brunotti, A Fiascarelli, A Cicalini, MGS Costa, AM Buckle, ... FEBS Journal, 2015 | 92 | 2015 |
| Nitrite and Nitrite Reductases: From Molecular Mechanisms to Significance in Human Health and Disease N Castiglione, S Rinaldo, G Giardina, V Stelitano, F Cutruzzolà Antioxidants & Redox Signaling, 2012 | 81 | 2012 |
| Identification by Virtual Screening and In Vitro Testing of Human DOPA Decarboxylase Inhibitors F Daidone, R Montioli, A Paiardini, B Cellini, A Macchiarulo, G Giardina, ... PloS one 7 (2), e31610, 2012 | 77 | 2012 |
| C-di-GMP Hydrolysis by Pseudomonas aeruginosa HD-GYP Phosphodiesterases: Analysis of the Reaction Mechanism and Novel Roles for pGpG V Stelitano, G Giardina, A Paiardini, N Castiglione, F Cutruzzolà, ... PLoS One 8 (9), e74920, 2013 | 75 | 2013 |
| The transcription factor DNR from Pseudomonas aeruginosa specifically requires nitric oxide and haem for the activation of a target promoter in Escherichia coli N Castiglione, S Rinaldo, G Giardina, F Cutruzzola Microbiology 155 (9), 2838-2844, 2009 | 66 | 2009 |
| Beyond nitrogen metabolism: nitric oxide, cyclic-di-GMP and bacterial biofilms S Rinaldo, G Giardina, F Mantoni, A Paone, F Cutruzzolà FEMS microbiology letters 365 (6), fny029, 2018 | 63 | 2018 |
| Investigating the Allosteric Regulation of YfiN from Pseudomonas aeruginosa: Clues from the Structure of the Catalytic Domain G Giardina, A Paiardini, S Fernicola, S Franceschini, S Rinaldo, ... PloS one 8 (11), e81324, 2013 | 59 | 2013 |
| A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells M Marani, A Paone, A Fiascarelli, A Macone, M Gargano, S Rinaldo, ... Oncotarget 7 (4), 4570, 2016 | 57 | 2016 |
| Probing the activity of diguanylate cyclases and c-di-GMP phosphodiesterases in real-time by CD spectroscopy V Stelitano, A Brandt, S Fernicola, S Franceschini, G Giardina, A Pica, ... Nucleic acids research 41 (7), e79-e79, 2013 | 53 | 2013 |
| In Silico Discovery and In Vitro Validation of Catechol-Containing Sulfonohydrazide Compounds as Potent Inhibitors of the Diguanylate Cyclase PleD S Fernicola, A Paiardini, G Giardina, G Rampioni, L Leoni, F Cutruzzolà, ... Journal of bacteriology 198 (1), 147-156, 2016 | 49 | 2016 |
| Structural basis of functional diversification of the HD-GYP domain revealed by the Pseudomonas aeruginosa PA4781 protein, which displays an unselective bimetallic binding site S Rinaldo, A Paiardini, V Stelitano, P Brunotti, L Cervoni, S Fernicola, ... Journal of bacteriology 197 (8), 1525-1535, 2015 | 44 | 2015 |
| A dramatic conformational rearrangement is necessary for the activation of DNR from Pseudomonas aeruginosa. Crystal structure of wild‐type DNR G Giardina, S Rinaldo, N Castiglione, M Caruso, F Cutruzzolà Proteins: Structure, Function, and Bioinformatics 77 (1), 174-180, 2009 | 44 | 2009 |
| Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase A Paiardini, A Fiascarelli, S Rinaldo, F Daidone, G Giardina, DR Koes, ... ChemMedChem 10 (3), 490-497, 2015 | 42 | 2015 |
| N-Acetylcysteine Serves as Substrate of 3-Mercaptopyruvate Sulfurtransferase and Stimulates Sulfide Metabolism in Colon Cancer Cells K Zuhra, CS Tomé, L Masi, G Giardina, G Paulini, F Malagrinò, E Forte, ... Cells 8 (8), 828, 2019 | 37 | 2019 |
| Synthesis of triazole-linked analogues of c-di-GMP and their interactions with diguanylate cyclase S Fernicola, I Torquati, A Paiardini, G Giardina, G Rampioni, M Messina, ... Journal of Medicinal Chemistry 58 (20), 8269-8284, 2015 | 37 | 2015 |
| The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells G Giardina, A Paone, A Tramonti, R Lucchi, M Marani, MC Magnifico, ... The FEBS Journal 285 (17), 3238-3253, 2018 | 36 | 2018 |
Francesca CutruzzolaSapienza University of RomeEmail verificata su uniroma1.it
