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Sara B. Linker
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The role of adult hippocampal neurogenesis in brain health and disease
T Toda, SL Parylak, SB Linker, FH Gage
Molecular psychiatry 24 (1), 67-87, 2019
5722019
Nuclear RNA-seq of single neurons reveals molecular signatures of activation
B Lacar, SB Linker, BN Jaeger, SR Krishnaswami, JJ Barron, MJE Kelder, ...
Nature communications 7 (1), 11022, 2016
4232016
Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons
SR Krishnaswami, RV Grindberg, M Novotny, P Venepally, B Lacar, ...
Nature protocols 11 (3), 499-524, 2016
4032016
The role of retrotransposable elements in ageing and age-associated diseases
V Gorbunova, A Seluanov, P Mita, W McKerrow, D Fenyö, JD Boeke, ...
Nature 596 (7870), 43-53, 2021
1762021
Nup153 interacts with Sox2 to enable bimodal gene regulation and maintenance of neural progenitor cells
T Toda, JY Hsu, SB Linker, L Hu, ST Schafer, J Mertens, FV Jacinto, ...
Cell stem cell 21 (5), 618-634. e7, 2017
1172017
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells
MC Marchetto, B Hrvoj-Mihic, BE Kerman, DX Yu, KC Vadodaria, ...
elife 8, e37527, 2019
1022019
Comparison of three targeted enrichment strategies on the SOLiD sequencing platform
DJ Hedges, T Guettouche, S Yang, G Bademci, A Diaz, A Andersen, ...
PloS one 6 (4), e18595, 2011
1002011
Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons
DA Reid, PJ Reed, JCM Schlachetzki, II Nitulescu, G Chou, EC Tsui, ...
Science 372 (6537), 91-94, 2021
752021
A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons
BN Jaeger, SB Linker, SL Parylak, JJ Barron, IS Gallina, CD Saavedra, ...
Nature communications 9 (1), 3084, 2018
672018
Prediction of response to drug therapy in psychiatric disorders
S Stern, S Linker, KC Vadodaria, MC Marchetto, FH Gage
Open biology 8 (5), 180031, 2018
602018
KLF4 N-terminal variance modulates induced reprogramming to pluripotency
SI Kim, F Oceguera-Yanez, R Hirohata, S Linker, K Okita, Y Yamada, ...
Stem Cell Reports 4 (4), 727-743, 2015
512015
An in vitro model of lissencephaly: expanding the role of DCX during neurogenesis
M Shahsavani, RJ Pronk, R Falk, M Lam, M Moslem, SB Linker, J Salma, ...
Molecular psychiatry 23 (7), 1674-1684, 2018
502018
Deficient LEF1 expression is associated with lithium resistance and hyperexcitability in neurons derived from bipolar disorder patients
R Santos, SB Linker, S Stern, APD Mendes, MN Shokhirev, G Erikson, ...
Molecular psychiatry 26 (6), 2440-2456, 2021
442021
Loss of the neural-specific BAF subunit ACTL6B relieves repression of early response genes and causes recessive autism
W Wenderski, L Wang, A Krokhotin, JJ Walsh, H Li, H Shoji, S Ghosh, ...
Proceedings of the National Academy of Sciences 117 (18), 10055-10066, 2020
382020
Sequencing, identification and mapping of primed L1 elements (SIMPLE) reveals significant variation in full length L1 elements between individuals
VA Streva, VE Jordan, S Linker, DJ Hedges, MA Batzer, PL Deininger
BMC genomics 16, 1-12, 2015
382015
Modeling brain disorders using induced pluripotent stem cells
KC Vadodaria, JR Jones, S Linker, FH Gage
Cold Spring Harbor Perspectives in Biology 12 (6), a035659, 2020
352020
Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability
T Bae, L Fasching, Y Wang, JH Shin, M Suvakov, Y Jang, S Norton, ...
Science 377 (6605), 511-517, 2022
332022
IGF-1 treatment causes unique transcriptional response in neurons from individuals with idiopathic autism
SB Linker, APD Mendes, MC Marchetto
Molecular Autism 11, 1-13, 2020
262020
Examining non-LTR retrotransposons in the context of the evolving primate brain
SB Linker, MC Marchetto, I Narvaiza, AM Denli, FH Gage
BMC biology 15, 1-8, 2017
262017
Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients
S Stern, S Lau, A Manole, I Rosh, MM Percia, R Ben Ezer, MN Shokhirev, ...
npj Parkinson's Disease 8 (1), 103, 2022
192022
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