| The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor ζ-chain and induce a regulatory phenotype in naive T cells F Fallarino, U Grohmann, S You, BC McGrath, DR Cavener, C Vacca, ... The Journal of Immunology 176 (11), 6752-6761, 2006 | 1271 | 2006 |
| Indoleamine 2, 3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells MT Pallotta, C Orabona, C Volpi, C Vacca, ML Belladonna, R Bianchi, ... Nature immunology 12 (9), 870-878, 2011 | 715 | 2011 |
| Aryl hydrocarbon receptor control of a disease tolerance defence pathway A Bessede, M Gargaro, MT Pallotta, D Matino, G Servillo, C Brunacci, ... Nature 511 (7508), 184-190, 2014 | 654 | 2014 |
| CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86 C Orabona, U Grohmann, ML Belladonna, F Fallarino, C Vacca, R Bianchi, ... Nature immunology 5 (11), 1134-1142, 2004 | 384 | 2004 |
| Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy U Grohmann, C Volpi, F Fallarino, S Bozza, R Bianchi, C Vacca, ... Nature medicine 13 (5), 579-586, 2007 | 376 | 2007 |
| A relay pathway between arginine and tryptophan metabolism confers immunosuppressive properties on dendritic cells G Mondanelli, R Bianchi, MT Pallotta, C Orabona, E Albini, A Iacono, ... Immunity 46 (2), 233-244, 2017 | 272 | 2017 |
| SOCS3 drives proteasomal degradation of indoleamine 2, 3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis C Orabona, MT Pallotta, C Volpi, F Fallarino, C Vacca, R Bianchi, ... Proceedings of the National Academy of Sciences 105 (52), 20828-20833, 2008 | 230 | 2008 |
| Kynurenine pathway enzymes in dendritic cells initiate tolerogenesis in the absence of functional IDO ML Belladonna, U Grohmann, P Guidetti, C Volpi, R Bianchi, MC Fioretti, ... The Journal of Immunology 177 (1), 130-137, 2006 | 216 | 2006 |
| Cutting edge: autocrine TGF-β sustains default tolerogenesis by IDO-competent dendritic cells ML Belladonna, C Volpi, R Bianchi, C Vacca, C Orabona, MT Pallotta, ... The Journal of Immunology 181 (8), 5194-5198, 2008 | 205 | 2008 |
| Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation F Fallarino, C Volpi, F Fazio, S Notartomaso, C Vacca, C Busceti, ... Nature medicine 16 (8), 897-902, 2010 | 173 | 2010 |
| Balancing inflammation and tolerance in vivo through dendritic cells by the commensal Candida albicans P Bonifazi, T Zelante, C D'Angelo, A De Luca, S Moretti, S Bozza, ... Mucosal immunology 2 (4), 362-374, 2009 | 166 | 2009 |
| Tryptophan catabolism generates autoimmune-preventive regulatory T cells F Fallarino, U Grohmann, S You, BC McGrath, DR Cavener, C Vacca, ... Transplant immunology 17 (1), 58-60, 2006 | 142 | 2006 |
| IDO mediates TLR9-driven protection from experimental autoimmune diabetes F Fallarino, C Volpi, T Zelante, C Vacca, M Calvitti, MC Fioretti, P Puccetti, ... The Journal of Immunology 183 (10), 6303-6312, 2009 | 126 | 2009 |
| Immunosuppression via tryptophan catabolism: the role of kynurenine pathway enzymes ML Belladonna, P Puccetti, C Orabona, F Fallarino, C Vacca, C Volpi, ... Transplantation 84 (1), S17-S20, 2007 | 125 | 2007 |
| High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9–TRIF pathway C Volpi, F Fallarino, MT Pallotta, R Bianchi, C Vacca, ML Belladonna, ... Nature communications 4 (1), 1852, 2013 | 117 | 2013 |
| Cutting edge: silencing suppressor of cytokine signaling 3 expression in dendritic cells turns CD28-Ig from immune adjuvant to suppressant C Orabona, ML Belladonna, C Vacca, R Bianchi, F Fallarino, C Volpi, ... The journal of immunology 174 (11), 6582-6586, 2005 | 109 | 2005 |
| Amino-acid sensing and degrading pathways in immune regulation U Grohmann, G Mondanelli, ML Belladonna, C Orabona, MT Pallotta, ... Cytokine & growth factor reviews 35, 37-45, 2017 | 86 | 2017 |
| Indoleamine 2, 3‐dioxygenase 1 (IDO1): an up‐to‐date overview of an eclectic immunoregulatory enzyme MT Pallotta, S Rossini, C Suvieri, A Coletti, C Orabona, A Macchiarulo, ... The FEBS journal 289 (20), 6099-6118, 2022 | 74 | 2022 |
| Positive allosteric modulation of indoleamine 2, 3-dioxygenase 1 restrains neuroinflammation G Mondanelli, A Coletti, FA Greco, MT Pallotta, C Orabona, A Iacono, ... Proceedings of the National Academy of Sciences 117 (7), 3848-3857, 2020 | 64 | 2020 |
| Cinnabarinic acid, an endogenous agonist of type-4 metabotropic glutamate receptor, suppresses experimental autoimmune encephalomyelitis in mice F Fazio, C Zappulla, S Notartomaso, C Busceti, A Bessede, P Scarselli, ... Neuropharmacology 81, 237-243, 2014 | 60 | 2014 |
