Mircea Ivan
Mircea Ivan
Associate Professor of Medicine, Indiana University
Verified email at iu.edu
Title
Cited by
Cited by
Year
HIFα targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing
M Ivan, K Kondo, H Yang, W Kim, J Valiando, M Ohh, A Salic, JM Asara, ...
Science 292 (5516), 464-468, 2001
48242001
Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel–Lindau protein
M Ohh, CW Park, M Ivan, MA Hoffman, TY Kim, LE Huang, N Pavletich, ...
Nature cell biology 2 (7), 423-427, 2000
16512000
A microRNA signature of hypoxia
R Kulshreshtha, M Ferracin, SE Wojcik, R Garzon, H Alder, ...
Molecular and cellular biology 27 (5), 1859-1867, 2007
11112007
Structure of an HIF-1α-pVHL complex: hydroxyproline recognition in signaling
JH Min, H Yang, M Ivan, F Gertler, WG Kaelin, NP Pavletich
Science 296 (5574), 1886-1889, 2002
7472002
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
M Ivan, T Haberberger, DC Gervasi, KS Michelson, V Günzler, K Kondo, ...
Proceedings of the National Academy of Sciences 99 (21), 13459-13464, 2002
6342002
MicroRNA regulation of DNA repair gene expression in hypoxic stress
ME Crosby, R Kulshreshtha, M Ivan, PM Glazer
Cancer research 69 (3), 1221-1229, 2009
4342009
von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF
MA Hoffman, M Ohh, H Yang, JM Klco, M Ivan, WG Kaelin Jr
Human molecular genetics 10 (10), 1019-1027, 2001
4122001
MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways
X Rao, G Di Leva, M Li, F Fang, C Devlin, C Hartman-Frey, ME Burow, ...
Oncogene 30 (9), 1082-1097, 2011
3422011
MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU
E Favaro, A Ramachandran, R McCormick, H Gee, C Blancher, M Crosby, ...
PloS one 5 (4), e10345, 2010
2962010
A microRNA component of the hypoxic response
R Kulshreshtha, RV Davuluri, GA Calin, M Ivan
Cell Death & Differentiation 15 (4), 667-671, 2008
2842008
An integrated approach for experimental target identification of hypoxia-induced miR-210
P Fasanaro, S Greco, M Lorenzi, M Pescatori, M Brioschi, R Kulshreshtha, ...
Journal of Biological Chemistry 284 (50), 35134-35143, 2009
2662009
The von Hippel–Lindau tumor suppressor protein
M Ivan, WG Kaelin Jr
Current opinion in genetics & development 11 (1), 27-34, 2001
2632001
miR‐210: More than a silent player in hypoxia
C Devlin, S Greco, F Martelli, M Ivan
IUBMB life 63 (2), 94-100, 2011
2552011
Hypoxia response and microRNAs: no longer two separate worlds
M Ivan, AL Harris, F Martelli, R Kulshreshtha
Journal of cellular and molecular medicine 12 (5a), 1426-1431, 2008
2212008
microRNA: emerging therapeutic targets in acute ischemic diseases
P Fasanaro, S Greco, M Ivan, MC Capogrossi, F Martelli
Pharmacology & therapeutics 125 (1), 92-104, 2010
1982010
Regulatory mechanisms of microRNAs involvement in cancer: the strange case of Dr Jekyll and Mr Hyde
M Fabbri, M Ivan, A Cimmino, M Negrini, GA Calin
Expert opinion on biological therapy 7 (7), 1009-1019, 2007
1932007
Activated ras and ret oncogenes induce over-expression of c-met (hepatocyte growth factor receptor) in human thyroid epithelial cells
M Ivan, JA Bond, M Prat, PM Comoglio, D Wynford-Thomas
Oncogene 14 (20), 2417-2423, 1997
1861997
Enhancing hematopoietic stem cell transplantation efficacy by mitigating oxygen shock
CR Mantel, HA O’Leary, BR Chitteti, XX Huang, S Cooper, G Hangoc, ...
Cell 161 (7), 1553-1565, 2015
1782015
Regulation of microRNA expression: the hypoxic component
R Kulshreshtha, M Ferracin, M Negrini, GA Calin, RV Davuluri, M Ivan
Cell cycle 6 (12), 1425-1430, 2007
1712007
Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER
T Van Den Beucken, E Koch, K Chu, R Rupaimoole, P Prickaerts, ...
Nature communications 5 (1), 1-13, 2014
1552014
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