Segui
Li Wen
Li Wen
Peking Union Medical College Hospital
Email verificata su pumch.cn
Titolo
Citata da
Citata da
Anno
Mitochondrial dysfunction, through impaired autophagy, leads to endoplasmic reticulum stress, deregulated lipid metabolism, and pancreatitis in animal models
G Biczo, ET Vegh, N Shalbueva, OA Mareninova, J Elperin, E Lotshaw, ...
Gastroenterology 154 (3), 689-703, 2018
3002018
Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP
R Mukherjee, OA Mareninova, IV Odinokova, W Huang, J Murphy, ...
Gut 65 (8), 1333-1346, 2016
2252016
Inhibitors of ORAI1 prevent cytosolic calcium-associated injury of human pancreatic acinar cells and acute pancreatitis in 3 mouse models
L Wen, S Voronina, MA Javed, M Awais, P Szatmary, D Latawiec, ...
Gastroenterology 149 (2), 481-492. e7, 2015
2202015
Upregulation of heat shock proteins (HSPA12A, HSP90B1, HSPA4, HSPA5 and HSPA6) in tumour tissues is associated with poor outcomes from HBV-related early-stage hepatocellular …
Z Yang, L Zhuang, P Szatmary, L Wen, H Sun, Y Lu, Q Xu, X Chen
International journal of medical sciences 12 (3), 256, 2015
2162015
Metformin uniquely prevents thrombosis by inhibiting platelet activation and mtDNA release
G Xin, Z Wei, C Ji, H Zheng, J Gu, L Ma, W Huang, SL Morris-Natschke, ...
Scientific reports 6 (1), 36222, 2016
1222016
The Orai Ca2+ channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis
RT Waldron, Y Chen, H Pham, A Go, HY Su, C Hu, L Wen, SZ Husain, ...
The Journal of physiology 597 (12), 3085-3105, 2019
1102019
Caffeine protects against experimental acute pancreatitis by inhibition of inositol 1, 4, 5-trisphosphate receptor-mediated Ca2+ release
W Huang, MC Cane, R Mukherjee, P Szatmary, X Zhang, V Elliott, ...
Gut 66 (2), 301-313, 2017
1092017
Transient high pressure in pancreatic ducts promotes inflammation and alters tight junctions via calcineurin signaling in mice
L Wen, TA Javed, D Yimlamai, A Mukherjee, X Xiao, SZ Husain
Gastroenterology 155 (4), 1250-1263. e5, 2018
642018
Small molecule inhibitors of cyclophilin D to protect mitochondrial function as a potential treatment for acute pancreatitis
ER Shore, M Awais, NM Kershaw, RR Gibson, S Pandalaneni, ...
Journal of medicinal chemistry 59 (6), 2596-2611, 2016
592016
Xanthohumol isolated from Humulus lupulus prevents thrombosis without increased bleeding risk by inhibiting platelet activation and mtDNA release
G Xin, Z Wei, C Ji, H Zheng, J Gu, L Ma, W Huang, SL Morris-Natschke, ...
Free Radical Biology and Medicine 108, 247-257, 2017
532017
Pancreatitis is an FGF21-deficient state that is corrected by replacement therapy
G Hernandez, T Luo, TA Javed, L Wen, MA Kalwat, K Vale, F Ammouri, ...
Science translational medicine 12 (525), eaay5186, 2020
472020
Effects of the mitochondria-targeted antioxidant mitoquinone in murine acute pancreatitis
W Huang, N Cash, L Wen, P Szatmary, R Mukherjee, J Armstrong, ...
Mediators of Inflammation 2015, 2015
452015
Prediction of the severity of acute pancreatitis on admission by urinary trypsinogen activation peptide: a meta-analysis
W Huang, K Altaf, T Jin, JJ Xiong, L Wen, MA Javed, M Johnstone, P Xue, ...
World journal of gastroenterology: WJG 19 (28), 4607, 2013
452013
Myeloid‐specific dopamine D2 receptor signalling controls inflammation in acute pancreatitis via inhibiting M1 macrophage
X Han, J Ni, Z Wu, J Wu, B Li, X Ye, J Dai, C Chen, J Xue, R Wan, L Wen, ...
British journal of pharmacology 177 (13), 2991-3008, 2020
422020
TRO40303 ameliorates alcohol-induced pancreatitis through reduction of fatty acid ethyl ester–induced mitochondrial injury and necrotic cell death
MA Javed, L Wen, M Awais, D Latawiec, W Huang, M Chvanov, ...
Pancreas 47 (1), 18-24, 2018
352018
Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine
X Zhang, T Jin, N Shi, L Yao, X Yang, C Han, L Wen, D Du, P Szatmary, ...
Frontiers in Physiology 9, 1922, 2019
332019
Targeted inhibition of pancreatic acinar cell calcineurin is a novel strategy to prevent post-ERCP pancreatitis
AI Orabi, L Wen, TA Javed, T Le, P Guo, S Sanker, D Ricks, K Boggs, ...
Cellular and molecular gastroenterology and hepatology 3 (1), 119-128, 2017
322017
Dihydrodiosgenin protects against experimental acute pancreatitis and associated lung injury through mitochondrial protection and PI3Kγ/Akt inhibition
Y Shen, L Wen, R Zhang, Z Wei, N Shi, Q Xiong, Q Xia, Z Xing, Z Zeng, ...
British Journal of Pharmacology 175 (10), 1621-1636, 2018
282018
Schisandrin B antagonizes cardiotoxicity induced by pirarubicin by inhibiting mitochondrial permeability transition pore (mPTP) opening and decreasing cardiomyocyte apoptosis
H Shi, H Tang, W Ai, Q Zeng, H Yang, F Zhu, Y Wei, R Feng, L Wen, P Pu, ...
Frontiers in Pharmacology 12, 733805, 2021
272021
Animal models: challenges and opportunities to determine optimal experimental models of pancreatitis and pancreatic cancer
JL Saloman, KM Albers, Z Cruz-Monserrate, BM Davis, M Edderkaoui, ...
Pancreas 48 (6), 759-779, 2019
272019
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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