Drug repurposing for COVID-19 using machine learning and mechanistic models of signal transduction circuits related to SARS-CoV-2 infection C Loucera, M Esteban-Medina, K Rian, MM Falco, J Dopazo, ... Signal transduction and targeted therapy 5 (1), 1-3, 2020 | 60 | 2020 |
miQC: An adaptive probabilistic framework for quality control of single-cell RNA-sequencing data AA Hippen, MM Falco, LM Weber, EP Erkan, K Zhang, JA Doherty, ... PLoS computational biology 17 (8), e1009290, 2021 | 46 | 2021 |
The pan-cancer pathological regulatory landscape MM Falco, M Bleda, J Carbonell-Caballero, J Dopazo Scientific reports 6, 2016 | 30 | 2016 |
Platform to study intracellular polystyrene nanoplastic pollution and clinical outcomes S Bojic, MM Falco, P Stojkovic, B Ljujic, M Gazdic Jankovic, L Armstrong, ... Stem Cells 38 (10), 1321-1325, 2020 | 29 | 2020 |
Using mechanistic models for the clinical interpretation of complex genomic variation M Peña-Chilet, M Esteban-Medina, MM Falco, K Rian, MR Hidalgo, ... Scientific reports 9 (1), 18937, 2019 | 23 | 2019 |
Mechanistic modeling of the SARS-CoV-2 disease map K Rian, M Esteban-Medina, MR Hidalgo, C Çubuk, MM Falco, C Loucera, ... BioData mining 14, 1-8, 2021 | 22 | 2021 |
A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids W Senkowski, L Gall-Mas, MM Falco, Y Li, K Lavikka, MC Kriegbaum, ... Developmental Cell 58 (12), 1106-1121. e7, 2023 | 17* | 2023 |
Cell‐to‐cell and type‐to‐type heterogeneity of signaling networks: insights from the crowd A Gabor, M Tognetti, A Driessen, J Tanevski, B Guo, W Cao, H Shen, T Yu, ... Molecular systems biology 17 (10), e10402, 2021 | 14 | 2021 |
Mechanistic models of signaling pathways deconvolute the glioblastoma single-cell functional landscape MM Falco, M Peña-Chilet, C Loucera, MR Hidalgo, J Dopazo NAR cancer 2 (2), zcaa011, 2020 | 14 | 2020 |
Genome-scale mechanistic modeling of signaling pathways made easy: A bioconductor/cytoscape/web server framework for the analysis of omic data K Rian, MR Hidalgo, C Çubuk, MM Falco, C Loucera, M Esteban-Medina, ... Computational and Structural Biotechnology Journal 19, 2968-2978, 2021 | 12 | 2021 |
Chemotherapy induces myeloid-driven spatial T-cell exhaustion in ovarian cancer IMP Launonen, EP Erkan, I Niemiec, A Junquera, M Hincapie-Otero, ... bioRxiv, 2024.03. 19.585657, 2024 | 2 | 2024 |
Studying the impact of CNVs on expression at single-cell resolution in HGSOC using autoencoders MM Falco, T Närhi, EP Erkan, J Hynninen, A Vähärautio Cancer Research 84 (6_Supplement), 893-893, 2024 | | 2024 |
Application of high-grade serous ovarian cancer organoids in functional precision medicine W Senkowski, L Gall-Mas, MM Falco, Y Li, K Lavikka, A Crispino, ... Cancer Research 84 (6_Supplement), 235-235, 2024 | | 2024 |
Locus-specific LINE-1 expression in clinical ovarian cancer specimens at the single-cell level A Perkiö, B Pradhan, F Genc, A Pirttikoski, S Pikkusaari, EP Erkan, ... Scientific Reports 14 (1), 4322, 2024 | | 2024 |
Tracing back primed resistance in cancer via sister cells J Dai, S Zheng, MM Falco, J Bao, J Eriksson, S Pikkusaari, S Forstén, ... Nature Communications 15 (1), 1158, 2024 | | 2024 |
Multi-Omics Analysis Reveals the Attenuation of the Interferon Pathway as a Driver of Chemo-Refractory Ovarian Cancer D Afenteva, R Yu, A Rajavuori, M Salvadores, IM Launonen, K Lavikka, ... bioRxiv, 2024.03. 28.587131, 2024 | | 2024 |
Transgelin 2 guards T cell lipid metabolic programming and anti-tumor function SM Hwang, D Awasthi, J Jeong, TA Sandoval, CS Chae, Y Ramos, C Tan, ... Research Square, 2023 | | 2023 |
Transgelin 2 guards T cell lipid metabolic programming and anti-tumor function J Cubillos-Ruiz, SM Hwang, D Awasthi, J Jeong, T Sandoval, CS Chae, ... | | 2023 |
Iron Chelation Therapy Elicits Innate Immune Control of Metastatic Ovarian Cancer J Cubillos-Ruiz, T Sandoval, CS Chae, C Salvagno, D Awasthi, ... | | 2023 |
Efficient establishment and utilization of a high-grade serous ovarian cancer organoid biobank W Senkowski, LG Mas, MM Falco, Y Li, K Lavikka, MC Kriegbaum, ... Cancer Research 82 (12_Supplement), 3069-3069, 2022 | | 2022 |