Alternative isoform regulation in human tissue transcriptomes ET Wang, R Sandberg, S Luo, I Khrebtukova, L Zhang, C Mayr, ... Nature 456 (7221), 470, 2008 | 4537 | 2008 |
Analysis and design of RNA sequencing experiments for identifying isoform regulation Y Katz, ET Wang, EM Airoldi, CB Burge Nature methods 7 (12), 1009, 2010 | 1190 | 2010 |
An abundance of ubiquitously expressed genes revealed by tissue transcriptome sequence data D Ramsköld, ET Wang, CB Burge, R Sandberg PLoS computational biology 5 (12), e1000598, 2009 | 804 | 2009 |
Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2 KM Parmar, HB Larman, G Dai, Y Zhang, ET Wang, SN Moorthy, JR Kratz, ... The Journal of clinical investigation 116 (1), 49-58, 2006 | 652 | 2006 |
Transcriptome-wide regulation of pre-mRNA splicing and mRNA localization by muscleblind proteins ET Wang, NAL Cody, S Jog, M Biancolella, TT Wang, DJ Treacy, S Luo, ... Cell 150 (4), 710-724, 2012 | 385 | 2012 |
MBNL proteins repress ES-cell-specific alternative splicing and reprogramming H Han, M Irimia, PJ Ross, HK Sung, B Alipanahi, L David, A Golipour, ... Nature 498 (7453), 241, 2013 | 264 | 2013 |
Biomechanical forces in atherosclerosis-resistant vascular regions regulate endothelial redox balance via phosphoinositol 3-kinase/Akt-dependent activation of Nrf2 G Dai, S Vaughn, Y Zhang, ET Wang, G Garcia-Cardena, MA Gimbrone Jr Circulation research 101 (7), 723-733, 2007 | 228 | 2007 |
Distal alternative last exons localize mRNAs to neural projections JM Taliaferro, M Vidaki, R Oliveira, S Olson, L Zhan, T Saxena, ET Wang, ... Molecular cell 61 (6), 821-833, 2016 | 149 | 2016 |
Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins ET Wang, AJ Ward, JM Cherone, J Giudice, TT Wang, DJ Treacy, ... Genome research 25 (6), 858-871, 2015 | 134 | 2015 |
Global regulation of alternative splicing during myogenic differentiation CS Bland, ET Wang, A Vu, MP David, JC Castle, JM Johnson, CB Burge, ... Nucleic acids research 38 (21), 7651-7664, 2010 | 125 | 2010 |
Design of a bioactive small molecule that targets the myotonic dystrophy type 1 RNA via an RNA motif–ligand database and chemical similarity searching R Parkesh, JL Childs-Disney, M Nakamori, A Kumar, E Wang, T Wang, ... Journal of the American Chemical Society 134 (10), 4731-4742, 2012 | 124 | 2012 |
Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development J Giudice, Z Xia, ET Wang, MA Scavuzzo, AJ Ward, A Kalsotra, W Wang, ... Nature communications 5, 3603, 2014 | 112 | 2014 |
Quantitative visualization of alternative exon expression from RNA-seq data Y Katz, ET Wang, J Silterra, S Schwartz, B Wong, H Thorvaldsdóttir, ... Bioinformatics 31 (14), 2400-2402, 2015 | 109 | 2015 |
Splice site strength–dependent activity and genetic buffering by poly-G runs X Xiao, Z Wang, M Jang, R Nutiu, ET Wang, CB Burge Nature structural & molecular biology 16 (10), 1094, 2009 | 109 | 2009 |
Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy F Freyermuth, F Rau, Y Kokunai, T Linke, C Sellier, M Nakamori, Y Kino, ... Nature communications 7, 11067, 2016 | 106 | 2016 |
Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics JE Dahlman, KJ Kauffman, Y Xing, TE Shaw, FF Mir, CC Dlott, R Langer, ... Proceedings of the National Academy of Sciences 114 (8), 2060-2065, 2017 | 78 | 2017 |
Mice with endogenous TDP‐43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis P Fratta, P Sivakumar, J Humphrey, K Lo, T Ricketts, H Oliveira, ... The EMBO journal 37 (11), 2018 | 75 | 2018 |
Myotonic dystrophy: approach to therapy CA Thornton, E Wang, EM Carrell Current opinion in genetics & development 44, 135-140, 2017 | 70 | 2017 |
Dysregulation of mRNA localization and translation in genetic disease ET Wang, JM Taliaferro, JA Lee, IP Sudhakaran, W Rossoll, C Gross, ... Journal of Neuroscience 36 (45), 11418-11426, 2016 | 69 | 2016 |
Impeding transcription of expanded microsatellite repeats by deactivated Cas9 BS Pinto, T Saxena, R Oliveira, HR Méndez-Gómez, JD Cleary, LT Denes, ... Molecular cell 68 (3), 479-490. e5, 2017 | 68 | 2017 |