| The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence FA Mallette, MF Gaumont-Leclerc, G Ferbeyre Genes & development 21 (1), 43-48, 2007 | 487 | 2007 |
| RNF8‐and RNF168‐dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites FA Mallette, F Mattiroli, G Cui, LC Young, MJ Hendzel, G Mer, TK Sixma, ... The EMBO journal 31 (8), 1865-1878, 2012 | 382 | 2012 |
| mTOR as a central regulator of lifespan and aging D Papadopoli, K Boulay, L Kazak, M Pollak, FA Mallette, I Topisirovic, ... F1000Research 8, 2019 | 323 | 2019 |
| DNA damage signaling and p53-dependent senescence after prolonged β-interferon stimulation O Moiseeva, FA Mallette, UK Mukhopadhyay, A Moores, G Ferbeyre Molecular biology of the cell 17 (4), 1583-1592, 2006 | 314 | 2006 |
| Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy M Oubaha, K Miloudi, A Dejda, V Guber, G Mawambo, MA Germain, ... Science translational medicine 8 (362), 362ra144-362ra144, 2016 | 217 | 2016 |
| Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation X Deschênes-Simard, MF Gaumont-Leclerc, V Bourdeau, F Lessard, ... Genes & development 27 (8), 900-915, 2013 | 208 | 2013 |
| Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy F Binet, G Cagnone, S Crespo-Garcia, M Hata, M Neault, A Dejda, ... Science 369 (6506), eaay5356, 2020 | 160 | 2020 |
| Cellular senescence in postmitotic cells: beyond growth arrest P Sapieha, FA Mallette Trends in cell biology 28 (8), 595-607, 2018 | 160 | 2018 |
| The DNA damage signaling pathway connects oncogenic stress to cellular senescence FA Mallette, G Ferbeyre Cell cycle 6 (15), 1831-1836, 2007 | 158 | 2007 |
| SOCS1 links cytokine signaling to p53 and senescence V Calabrese, FA Mallette, X Deschênes-Simard, S Ramanathan, ... Molecular cell 36 (5), 754-767, 2009 | 155 | 2009 |
| The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway M Carbonneau, L M. Gagné, ME Lalonde, MA Germain, A Motorina, ... Nature communications 7 (1), 12700, 2016 | 154 | 2016 |
| Targeting the senescence-overriding cooperative activity of structurally unrelated H3K9 demethylases in melanoma Y Yu, K Schleich, B Yue, S Ji, P Lohneis, K Kemper, MR Silvis, N Qutob, ... Cancer cell 33 (2), 322-336. e8, 2018 | 142 | 2018 |
| Noncanonical NF-κB pathway controls the production of type I interferons in antiviral innate immunity J Jin, H Hu, HS Li, J Yu, Y Xiao, GC Brittain, Q Zou, X Cheng, FA Mallette, ... Immunity 40 (3), 342-354, 2014 | 139 | 2014 |
| The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer*♦ S Daou, I Hammond-Martel, N Mashtalir, H Barbour, J Gagnon, ... Journal of Biological Chemistry 290 (48), 28643-28663, 2015 | 136 | 2015 |
| JMJD2A promotes cellular transformation by blocking cellular senescence through transcriptional repression of the tumor suppressor CHD5 FA Mallette, S Richard Cell reports 2 (5), 1233-1243, 2012 | 130 | 2012 |
| Ablation of PRMT6 reveals a role as a negative transcriptional regulator of the p53 tumor suppressor M Neault, FA Mallette, G Vogel, J Michaud-Levesque, S Richard Nucleic acids research 40 (19), 9513-9521, 2012 | 124 | 2012 |
| Human fibroblasts require the Rb family of tumor suppressors, but not p53, for PML-induced senescence FA Mallette, S Goumard, MF Gaumont-Leclerc, O Moiseeva, G Ferbeyre Oncogene 23 (1), 91-99, 2004 | 121 | 2004 |
| Oncogenic activities of IDH1/2 mutations: from epigenetics to cellular signaling LM Gagné, K Boulay, I Topisirovic, MÉ Huot, FA Mallette Trends in cell biology 27 (10), 738-752, 2017 | 114 | 2017 |
| Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition S Crespo-Garcia, PR Tsuruda, A Dejda, RD Ryan, F Fournier, SY Chaney, ... Cell metabolism 33 (4), 818-832. e7, 2021 | 92 | 2021 |
| miR-137 modulates a tumor suppressor network-inducing senescence in pancreatic cancer cells M Neault, FA Mallette, S Richard Cell reports 14 (8), 1966-1978, 2016 | 90 | 2016 |
