John Karanicolas
John Karanicolas
Molecular Therapeutics Group, Fox Chase Cancer Center
Verified email at fccc.edu - Homepage
Title
Cited by
Cited by
Year
ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules
A Leaver-Fay, M Tyka, SM Lewis, OF Lange, J Thompson, R Jacak, ...
Methods in enzymology 487, 545-574, 2011
13862011
MMTSB Tool Set: enhanced sampling and multiscale modeling methods for applications in structural biology
M Feig, J Karanicolas, CL Brooks III
Journal of Molecular Graphics and Modelling 22 (5), 377-395, 2004
8422004
MMTSB Tool Set: enhanced sampling and multiscale modeling methods for applications in structural biology
M Feig, J Karanicolas, CL Brooks III
Journal of Molecular Graphics and Modelling 22 (5), 377-395, 2004
8422004
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
SA Sievers, J Karanicolas, HW Chang, A Zhao, L Jiang, O Zirafi, ...
Nature 475 (7354), 96-100, 2011
4122011
The origins of asymmetry in the folding transition states of protein L and protein G
J Karanicolas, CL Brooks III
Protein Science 11 (10), 2351-2361, 2002
3832002
The 3D profile method for identifying fibril-forming segments of proteins
MJ Thompson, SA Sievers, J Karanicolas, MI Ivanova, D Baker, ...
Proceedings of the National Academy of Sciences 103 (11), 4074-4078, 2006
3782006
Atomic accuracy in predicting and designing noncanonical RNA structure
R Das, J Karanicolas, D Baker
Nature methods 7 (4), 291-294, 2010
3072010
Improved Gō-like models demonstrate the robustness of protein folding mechanisms towards non-native interactions
J Karanicolas, CL Brooks III
Journal of molecular biology 334 (2), 309-325, 2003
2172003
A de novo protein binding pair by computational design and directed evolution
J Karanicolas, JE Corn, I Chen, LA Joachimiak, O Dym, SH Peck, ...
Molecular cell 42 (2), 250-260, 2011
1672011
The structural basis for biphasic kinetics in the folding of the WW domain from a formin-binding protein: Lessons for protein design?
J Karanicolas, CL Brooks
Proceedings of the National Academy of Sciences 100 (7), 3954-3959, 2003
1382003
Computational design of affinity and specificity at protein–protein interfaces
J Karanicolas, B Kuhlman
Current opinion in structural biology 19 (4), 458-463, 2009
1332009
Musashi RNA-binding proteins as cancer drivers and novel therapeutic targets
AE Kudinov, J Karanicolas, EA Golemis, Y Boumber
Clinical Cancer Research 23 (9), 2143-2153, 2017
1122017
Allostery in its many disguises: from theory to applications
SJ Wodak, E Paci, NV Dokholyan, IN Berezovsky, A Horovitz, J Li, ...
Structure 27 (4), 566-578, 2019
1042019
Natural product (−)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1
L Lan, C Appelman, AR Smith, J Yu, S Larsen, RT Marquez, H Liu, X Wu, ...
Molecular oncology 9 (7), 1406-1420, 2015
852015
Targeting CDK9 reactivates epigenetically silenced genes in cancer
H Zhang, S Pandey, M Travers, H Sun, G Morton, J Madzo, W Chung, ...
Cell 175 (5), 1244-1258. e26, 2018
752018
Druggable protein interaction sites are more predisposed to surface pocket formation than the rest of the protein surface
DK Johnson, J Karanicolas
PLoS Comput Biol 9 (3), e1002951, 2013
742013
Integrating folding kinetics and protein function: Biphasic kinetics and dual binding specificity in a WW domain
J Karanicolas, CL Brooks
Proceedings of the National Academy of Sciences 101 (10), 3432-3437, 2004
702004
Site-specific incorporation of photoisomerizable azobenzene groups into ribonuclease S
D Liu, J Karanicolas, C Yu, Z Zhang, GA Woolley
Bioorganic & Medicinal Chemistry Letters 7 (20), 2677-2680, 1997
611997
MMTSB tool set
M Feig, J Karanicolas, CL Brooks III
MMTSB NIH Research Resource, The Scripps Research Institute, 2001
57*2001
Macromolecular modeling and design in Rosetta: recent methods and frameworks
JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ...
Nature methods 17 (7), 665-680, 2020
542020
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Articles 1–20