Simone Brioschi
Simone Brioschi
Washington University School of Medicine
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Age-related myelin degradation burdens the clearance function of microglia during aging
S Safaiyan, N Kannaiyan, N Snaidero, S Brioschi, K Biber, S Yona, ...
Nature neuroscience 19 (8), 995-998, 2016
TREM2 modulation remodels the tumor myeloid landscape enhancing anti-PD-1 immunotherapy
M Molgora, E Esaulova, W Vermi, J Hou, Y Chen, J Luo, S Brioschi, ...
Cell 182 (4), 886-900. e17, 2020
Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma
A Cugurra, T Mamuladze, J Rustenhoven, T Dykstra, G Beroshvili, ...
Science 373 (6553), eabf7844, 2021
Comprehensive profiling of an aging immune system reveals clonal GZMK+ CD8+ T cells as conserved hallmark of inflammaging
DA Mogilenko, O Shpynov, PS Andhey, L Arthur, A Swain, E Esaulova, ...
Immunity 54 (1), 99-115. e12, 2021
Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders
S Brioschi, WL Wang, V Peng, M Wang, I Shchukina, ZJ Greenberg, ...
Science 373 (6553), eabf9277, 2021
Targeting neuroinflammation to treat Alzheimer’s disease
A Ardura-Fabregat, E Boddeke, A Boza-Serrano, S Brioschi, ...
CNS drugs 31, 1057-1082, 2017
Altered microglia morphology and higher resilience to stress-induced depression-like behavior in CX3CR1-deficient mice
S Hellwig, S Brioschi, S Dieni, L Frings, A Masuch, T Blank, K Biber
Brain, Behavior, and Immunity 55, 126-137, 2016
TREM2 drives microglia response to amyloid-β via SYK-dependent and-independent pathways
S Wang, R Sudan, V Peng, Y Zhou, S Du, CM Yuede, T Lei, J Hou, Z Cai, ...
Cell 185 (22), 4153-4169. e19, 2022
Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer’s disease
DC Ellwanger, S Wang, S Brioschi, Z Shao, L Green, R Case, D Yoo, ...
Proceedings of the National Academy of Sciences 118 (3), e2017742118, 2021
Neuroinflammation and neurodegeneration in human brain at single-cell resolution
M Colonna, S Brioschi
Nature Reviews Immunology 20 (2), 81-82, 2020
Brain parenchymal and extraparenchymal macrophages in development, homeostasis, and disease
S Brioschi, Y Zhou, M Colonna
The Journal of Immunology 204 (2), 294-305, 2020
Neurodegeneration and neuroinflammation are linked, but independent of alpha‐synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease
P Garcia, W Jürgens‐Wemheuer, O Uriarte Huarte, A Michelucci, ...
Glia 70 (5), 935-960, 2022
Activation of EP2 receptor suppresses poly(I: C) and LPS‐mediated inflammation in primary microglia and organotypic hippocampal slice cultures: Contributing role …
NM Yousif, ACP de Oliveira, S Brioschi, M Huell, K Biber, BL Fiebich
Glia 66 (4), 708-724, 2018
Detection of synaptic proteins in microglia by flow cytometry
S Brioschi, P d’Errico, LS Amann, H Janova, SM Wojcik, ...
Frontiers in molecular neuroscience 13, 149, 2020
Effects of cytosine methylation on DNA morphology: An atomic force microscopy study
V Cassina, M Manghi, D Salerno, A Tempestini, V Iadarola, L Nardo, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (1), 1-7, 2016
Exploring the impact of TREM2 in tumor-associated macrophages
D Khantakova, S Brioschi, M Molgora
Vaccines 10 (6), 943, 2022
Platinum-based drugs and DNA interactions studied by single-molecule and bulk measurements
D Salerno, GL Beretta, G Zanchetta, S Brioschi, M Cristofalo, N Missana, ...
Biophysical Journal 110 (10), 2151-2161, 2016
A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages
S Brioschi, JA Belk, V Peng, M Molgora, PF Rodrigues, KM Nguyen, ...
Immunity 56 (5), 1027-1045. e8, 2023
The CNS immune-privilege goes down the drain (age)
S Brioschi, M Colonna
Trends in Pharmacological Sciences 40 (1), 1-3, 2019
Fluorimetric detection of the earliest events in amyloid β oligomerization and its inhibition by pharmacologically active liposomes
L Nardo, F Re, S Brioschi, E Cazzaniga, A Orlando, S Minniti, M Lamperti, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (4), 746-756, 2016
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