In vivo and neuropathology data support locus coeruleus integrity as indicator of Alzheimer’s disease pathology and cognitive decline HIL Jacobs, JA Becker, K Kwong, N Engels-Domínguez, PC Prokopiou, ... Science Translational Medicine 13 (612), eabj2511, 2021 | 124 | 2021 |
Lower novelty-related locus coeruleus function is associated with Aβ-related cognitive decline in clinically healthy individuals PC Prokopiou, N Engels-Domínguez, KV Papp, MR Scott, AP Schultz, ... Nature Communications 13 (1), 1571, 2022 | 33 | 2022 |
Waning locus coeruleus integrity precedes cortical tau accrual in preclinical autosomal dominant Alzheimer's disease HIL Jacobs, JA Becker, K Kwong, D Munera, L Ramirez‐Gomez, ... Alzheimer's & Dementia 19 (1), 169-180, 2023 | 15 | 2023 |
State-of-the-art imaging of neuromodulatory subcortical systems in aging and Alzheimer’s disease: Challenges and opportunities N Engels-Domínguez, EA Koops, PC Prokopiou, M Van Egroo, ... Neuroscience & Biobehavioral Reviews 144, 104998, 2023 | 9 | 2023 |
Association of Novelty-Related Locus Coeruleus Function With Entorhinal Tau Deposition and Memory Decline in Preclinical Alzheimer Disease PC Prokopiou, N Engels-Domínguez, AP Schultz, J Sepulcre, EA Koops, ... Neurology 101 (12), e1206-e1217, 2023 | 4 | 2023 |
Hypoconnectivity between locus coeruleus and medial temporal lobe during novelty predicts accelerated Aβ‐related cognitive decline: The locus coeruleus: Nexus of behavioral and … N Engels, PC Prokopiou, FO Uquillas, MR Scott, AP Schultz, KV Papp, ... Alzheimer's & Dementia 16, e041323, 2020 | 2 | 2020 |
High-Resolution Structural Brainstem Nuclei: Locus Coeruleus Integrity as Potential Biomarker of Alzheimer’s Disease-Related Phenotypes H Jacobs, JA Becker, K Kwong, N Engels-Dominguez, P Prokopiou, ... Biological Psychiatry 91 (9), S31, 2022 | 1 | 2022 |
Atrophy links lower novelty‐related locus coeruleus connectivity to cognitive decline in preclinical AD C Schneider, PC Prokopiou, KV Papp, N Engels‐Domínguez, S Hsieh, ... Alzheimer's & Dementia, 2024 | | 2024 |
Preliminary validation of the Stress and Adversity Inventory for Adults (Adult STRAIN) in Dutch and its associations with in‐vivo locus coeruleus integrity N Engels, JM Riphagen, M Van Egroo, CM Spahr, GM Slavich, ... Alzheimer's & Dementia 19, e082786, 2023 | | 2023 |
Vascular health is associated with locus coeruleus‐related entorhinal tau deposition JM Riphagen, JP Chhatwal, A Becker, K Kwong, N Engels, WYW Yau, ... Alzheimer's & Dementia 18, e066731, 2022 | | 2022 |
Lower in‐vivo locus coeruleus integrity is associated with lower cortical thickness in older individuals with elevated Alzheimer’s pathology N Engels, S Hsieh, C Schneider, PC Prokopiou, AP Schultz, JM Riphagen, ... Alzheimer's & Dementia 18, e067421, 2022 | | 2022 |
Lower novelty‐related locus coeruleus function is associated with entorhinal tau‐mediated memory decline in older individuals. PC Prokopiou, N Engels, C Schneider, AP Schultz, J Sepulcre, ... Alzheimer's & Dementia 18, e067706, 2022 | | 2022 |
Locus coeruleus integrity as a proxy of initial tau burden: in vivo versus ex vivo observations HIL Jacobs, A Becker, K Kwong, N Engels, PC Prokopiou, KV Papp, ... Alzheimer's & Dementia 17, e056391, 2021 | | 2021 |
Lower locus coeruleus activity during novelty predicts cognitive decline in clinically unimpaired older individuals NE Domínguez, PC Prokopiou, FO Uquillas, MR Scott, AP Schultz, ... | | |