The EGF-CFC protein one-eyed pinhead is essential for nodal signaling K Gritsman, J Zhang, S Cheng, E Heckscher, WS Talbot, AF Schier Cell 97 (1), 121-132, 1999 | 813 | 1999 |
Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation C Meno, K Gritsman, S Ohishi, Y Ohfuji, E Heckscher, K Mochida, ... Molecular cell 4 (3), 287-298, 1999 | 446 | 1999 |
Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice MG Kharas, R Okabe, JJ Ganis, M Gozo, T Khandan, M Paktinat, ... Blood, The Journal of the American Society of Hematology 115 (7), 1406-1415, 2010 | 332 | 2010 |
Nodal signaling patterns the organizer K Gritsman, WS Talbot, AF Schier Development 127 (5), 921-932, 2000 | 299 | 2000 |
Conserved requirement for EGF–CFC genes in vertebrate left–right axis formation YT Yan, K Gritsman, J Ding, RD Burdine, JMD Corrales, SM Price, ... Genes & development 13 (19), 2527-2537, 1999 | 296 | 1999 |
Control of the innate immune response by the mevalonate pathway MK Akula, M Shi, Z Jiang, CE Foster, D Miao, AS Li, X Zhang, RM Gavin, ... Nature immunology 17 (8), 922-929, 2016 | 176 | 2016 |
RICTOR Amplification Defines a Novel Subset of Patients with Lung Cancer Who May Benefit from Treatment with mTORC1/2 Inhibitors H Cheng, Y Zou, JS Ross, K Wang, X Liu, B Halmos, SM Ali, H Liu, ... Cancer discovery 5 (12), 1262-1270, 2015 | 111 | 2015 |
Inflammatory signaling pathways in preleukemic and leukemic stem cells S Hemmati, T Haque, K Gritsman Frontiers in oncology 7, 265, 2017 | 101 | 2017 |
Mutations in G protein β subunits promote transformation and kinase inhibitor resistance A Yoda, G Adelmant, J Tamburini, B Chapuy, N Shindoh, Y Yoda, ... Nature medicine 21 (1), 71-75, 2015 | 97 | 2015 |
IL1RAP potentiates multiple oncogenic signaling pathways in AML K Mitchell, L Barreyro, TI Todorova, SJ Taylor, I Antony-Debré, ... Journal of Experimental Medicine 215 (6), 1709-1727, 2018 | 80 | 2018 |
North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies UA Shah, EY Chung, O Giricz, K Pradhan, K Kataoka, S Gordon-Mitchell, ... Blood, The Journal of the American Society of Hematology 132 (14), 1507-1518, 2018 | 73 | 2018 |
Epigenetically aberrant stroma in MDS propagates disease via Wnt/β-catenin activation TD Bhagat, S Chen, M Bartenstein, AT Barlowe, D Von Ahrens, ... Cancer research 77 (18), 4846-4857, 2017 | 70 | 2017 |
Axicabtagene ciloleucel CD19 CAR-T cell therapy results in high rates of systemic and neurologic remissions in ten patients with refractory large B cell lymphoma including two … A Abbasi, S Peeke, N Shah, J Mustafa, F Khatun, A Lombardo, M Abreu, ... Journal of hematology & oncology 13, 1-4, 2020 | 69 | 2020 |
Contributions of DNA polymerase subdomains to the RNase H activity of human immunodeficiency virus type 1 reverse transcriptase JS Smith, K Gritsman, MJ Roth Journal of virology 68 (9), 5721-5729, 1994 | 67 | 1994 |
Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110α K Gritsman, H Yuzugullu, T Von, H Yan, L Clayton, C Fritsch, SM Maira, ... The Journal of clinical investigation 124 (4), 1794-1809, 2014 | 65 | 2014 |
PAK1 is a therapeutic target in acute myeloid leukemia and myelodysplastic syndrome A Pandolfi, RF Stanley, Y Yu, B Bartholdy, G Pendurti, K Gritsman, ... Blood, The Journal of the American Society of Hematology 126 (9), 1118-1127, 2015 | 62 | 2015 |
A PI3K p110β–Rac signalling loop mediates Pten-loss-induced perturbation of haematopoiesis and leukaemogenesis H Yuzugullu, L Baitsch, T Von, A Steiner, H Tong, J Ni, LK Clayton, ... Nature communications 6 (1), 8501, 2015 | 47 | 2015 |
High prevalence and allele burden-independent prognostic importance of p53 mutations in an inner-city MDS/AML cohort S Goel, J Hall, K Pradhan, C Hirsch, B Przychodzen, A Shastri, I Mantzaris, ... Leukemia 30 (8), 1793-1795, 2016 | 35 | 2016 |
PI3K alpha and delta promote hematopoietic stem cell activation S Hemmati, T Sinclair, M Tong, B Bartholdy, RO Okabe, K Ames, ... JCI insight 4 (13), 2019 | 34 | 2019 |
Signaling pathways in leukemic stem cells LM Gurska, K Ames, K Gritsman Leukemia Stem Cells in Hematologic Malignancies, 1-39, 2019 | 23 | 2019 |