| V (D) J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes DB Roth, JP Menetski, PB Nakajima, MJ Bosma, M Gellert Cell 70 (6), 983-991, 1992 | 651* | 1992 |
| Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction DB Roth, JH Wilson Molecular and cellular biology 6 (12), 4295-4304, 1986 | 593 | 1986 |
| Modernizing the nonhomologous end-joining repertoire: alternative and classical NHEJ share the stage L Deriano, DB Roth Annual review of genetics 47, 433-455, 2013 | 544 | 2013 |
| Growth retardation and leaky SCID phenotype of Ku70-deficient mice Y Gu, KJ Seidl, GA Rathbun, C Zhu, JP Manis, N Van Der Stoep, ... Immunity 7 (5), 653-665, 1997 | 529 | 1997 |
| Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V (D) J recombination intermediates C Zhu, MA Bogue, DS Lim, P Hasty, DB Roth Cell 86 (3), 379-389, 1996 | 512 | 1996 |
| Mechanisms of nonhomologous recombination in mammalian cells DB Roth, TN Porter, JH Wilson Molecular and cellular biology, 1985 | 388 | 1985 |
| Rag mutations reveal robust alternative end joining B Corneo, RL Wendland, L Deriano, X Cui, IA Klein, SY Wong, S Arnal, ... Nature 449 (7161), 483-486, 2007 | 378 | 2007 |
| Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells FA di Fagagna, MP Hande, WM Tong, D Roth, PM Lansdorp, ZQ Wang, ... Current Biology 11 (15), 1192-1196, 2001 | 356 | 2001 |
| Double-strand break repair in Ku86-and XRCC4-deficient cells EB Kabotyanski, L Gomelsky, JO Han, DB Roth, TD Stamato Nucleic acids research 26 (23), 5333-5342, 1998 | 307 | 1998 |
| RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination GS Lee, MB Neiditch, SS Salus, DB Roth Cell 117 (2), 171-184, 2004 | 261 | 2004 |
| Cancer predisposition and hematopoietic failure in Rad50S/S mice CF Bender, ML Sikes, R Sullivan, LE Huye, MM Le Beau, DB Roth, ... Genes & development 16 (17), 2237-2251, 2002 | 254 | 2002 |
| Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V (D) J recombination MA Landree, JA Wibbenmeyer, DB Roth Genes & development 13 (23), 3059-3069, 1999 | 245 | 1999 |
| V (D) J recombination: mechanism, errors, and fidelity DB Roth Mobile DNA III, 311-324, 2015 | 242 | 2015 |
| Illegitimate recombination in mammalian cells. D Roth Genetic recombination, 621-653, 1988 | 234 | 1988 |
| V (D) J recombination in mouse thymocytes: double-strand breaks near T cell receptor δ rearrangement signals DB Roth, PB Nakajima, JP Menetski, MJ Bosma, M Gellert Cell 69 (1), 41-53, 1992 | 228 | 1992 |
| Characterization of broken DNA molecules associated with V (D) J recombination. DB Roth, C Zhu, M Gellert Proceedings of the National Academy of Sciences 90 (22), 10788-10792, 1993 | 203 | 1993 |
| Relative rates of homologous and nonhomologous recombination in transfected DNA. DB Roth, JH Wilson Proceedings of the National Academy of Sciences 82 (10), 3355-3359, 1985 | 180 | 1985 |
| V (D) J recombination in Ku86-deficient mice: distinct effects on coding, signal, and hybrid joint formation MA Bogue, C Wang, C Zhu, DB Roth Immunity 7 (1), 37-47, 1997 | 174 | 1997 |
| Restraining the v (d) j recombinase DB Roth Nature Reviews Immunology 3 (8), 656-666, 2003 | 154 | 2003 |
| Repair and Recombination: How to make ends meet DB Roth, T Lindahl, M Gellert Current biology 5 (5), 496-499, 1995 | 145 | 1995 |
John F KearneyProfessor of Microbiology, University of Alabama at BirminghamVerified email at uab.edu
