Stationary phase gene expression of Mycobacterium tuberculosis following a progressive nutrient depletion: a model for persistent organisms? T Hampshire, S Soneji, J Bacon, BW James, J Hinds, K Laing, RA Stabler, ... Tuberculosis 84 (3-4), 228-238, 2004 | 267 | 2004 |
The influence of reduced oxygen availability on pathogenicity and gene expression in Mycobacterium tuberculosis J Bacon, BW James, L Wernisch, A Williams, KA Morley, GJ Hatch, ... tuberculosis 84 (3-4), 205-217, 2004 | 190 | 2004 |
Lipid composition and transcriptional response of Mycobacterium tuberculosis grown under iron-limitation in continuous culture: identification of a novel wax ester J Bacon, LG Dover, KA Hatch, Y Zhang, JM Gomes, S Kendall, ... Microbiology 153 (5), 1435-1444, 2007 | 99 | 2007 |
Comparative transcriptomics reveals key gene expression differences between the human and bovine pathogens of the Mycobacterium tuberculosis complex P Golby, KA Hatch, J Bacon, R Cooney, P Riley, J Allnutt, J Hinds, ... Microbiology 153 (10), 3323-3336, 2007 | 85 | 2007 |
Non-replicating Mycobacterium tuberculosis elicits a reduced infectivity profile with corresponding modifications to the cell wall and extracellular matrix J Bacon, LJ Alderwick, JA Allnutt, E Gabasova, R Watson, KA Hatch, ... PloS one 9 (2), e87329, 2014 | 74 | 2014 |
Time series analysis and mechanistic modelling of heterogeneity and sero-reversion in antibody responses to mild SARS‑CoV-2 infection C Manisty, TA Treibel, M Jensen, A Semper, G Joy, RK Gupta, ... EBioMedicine 65, 2021 | 64 | 2021 |
Mode of action of kanglemycin A, an ansamycin natural product that is active against rifampicin-resistant Mycobacterium tuberculosis H Mosaei, V Molodtsov, B Kepplinger, J Harbottle, CW Moon, RE Jeeves, ... Molecular cell 72 (2), 263-274. e5, 2018 | 57 | 2018 |
Selection of novel TB vaccine candidates and their evaluation as DNA vaccines against aerosol challenge J Vipond, R Vipond, E Allen-Vercoe, SO Clark, GJ Hatch, KE Gooch, ... Vaccine 24 (37-39), 6340-6350, 2006 | 50 | 2006 |
A flow cytometry method for rapidly assessing Mycobacterium tuberculosis responses to antibiotics with different modes of action CL Hendon-Dunn, KS Doris, SR Thomas, JC Allnutt, AAN Marriott, ... Antimicrobial agents and chemotherapy 60 (7), 3869-3883, 2016 | 47 | 2016 |
Mycobacterium tuberculosis Is Resistant to Isoniazid at a Slow Growth Rate by Single Nucleotide Polymorphisms in katG Codon Ser315 RE Jeeves, AAN Marriott, ST Pullan, KA Hatch, JC Allnutt, I Freire-Martin, ... PloS one 10 (9), e0138253, 2015 | 45 | 2015 |
Quantification of global transcription patterns in prokaryotes using spotted microarrays B Sidders, M Withers, SL Kendall, J Bacon, SJ Waddell, J Hinds, P Golby, ... Genome Biology 8, 1-13, 2007 | 41 | 2007 |
An assay to compare the infectivity of Mycobacterium tuberculosis isolates based on aerosol infection of guinea pigs and assessment of bacteriology A Williams, BW James, J Bacon, KA Hatch, GJ Hatch, GA Hall, PD Marsh Tuberculosis 85 (3), 177-184, 2005 | 33 | 2005 |
Enhanced heterogeneity of rpoB in Mycobacterium tuberculosis found at low pH C Jenkins, J Bacon, J Allnutt, KA Hatch, A Bose, DM O'Sullivan, C Arnold, ... Journal of antimicrobial chemotherapy 63 (6), 1118-1120, 2009 | 29 | 2009 |
Transcriptional responses of Mycobacterium tuberculosis exposed to adverse conditions in vitro J Bacon, PD Marsh Current molecular medicine 7 (3), 277-286, 2007 | 27 | 2007 |
Mycobacterial antigens expressed under low oxygen tension BW James, J Bacon, P Marsh US Patent 7,393,539, 2008 | 26 | 2008 |
The effect of growth rate on pyrazinamide activity in Mycobacterium tuberculosis - insights for early bactericidal activity? ST Pullan, JC Allnutt, R Devine, KA Hatch, RE Jeeves, CL Hendon-Dunn, ... BMC Infectious Diseases 16, 1-11, 2016 | 19 | 2016 |
Utilisation of the Prestwick Chemical Library to identify drugs that inhibit the growth of mycobacteria P Kanvatirth, RE Jeeves, J Bacon, GS Besra, LJ Alderwick PLoS One 14 (3), e0213713, 2019 | 16 | 2019 |
Noncytotoxic Pyrrolobenzodiazepine–Ciprofloxacin Conjugate with Activity against Mycobacterium tuberculosis P Picconi, R Jeeves, CW Moon, S Jamshidi, KS Nahar, M Laws, J Bacon, ... ACS omega 4 (25), 20873-20881, 2019 | 13 | 2019 |
Hazard Group 3 agent decontamination using hydrogen peroxide vapour in a class III microbiological safety cabinet T Pottage, S Lewis, A Lansley, S Fraser, C Hendon‐Dunn, J Bacon, ... Journal of applied microbiology 128 (1), 116-123, 2020 | 12 | 2020 |
In vitro gene expression dissected: chemostat surgery for Mycobacterium tuberculosis BW James, J Bacon, T Hampshire, K Morley, PD Marsh Comparative and functional genomics 3 (4), 345-347, 2002 | 12 | 2002 |