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Dr Joanna Bacon
Dr Joanna Bacon
Principal Investigator, TB Research, Public Health England
Verified email at phe.gov.uk
Title
Cited by
Cited by
Year
Stationary phase gene expression of Mycobacterium tuberculosis following a progressive nutrient depletion: a model for persistent organisms?
T Hampshire, S Soneji, J Bacon, BW James, J Hinds, K Laing, RA Stabler, ...
Tuberculosis 84 (3-4), 228-238, 2004
2672004
The influence of reduced oxygen availability on pathogenicity and gene expression in Mycobacterium tuberculosis
J Bacon, BW James, L Wernisch, A Williams, KA Morley, GJ Hatch, ...
tuberculosis 84 (3-4), 205-217, 2004
1902004
Lipid composition and transcriptional response of Mycobacterium tuberculosis grown under iron-limitation in continuous culture: identification of a novel wax ester
J Bacon, LG Dover, KA Hatch, Y Zhang, JM Gomes, S Kendall, ...
Microbiology 153 (5), 1435-1444, 2007
992007
Comparative transcriptomics reveals key gene expression differences between the human and bovine pathogens of the Mycobacterium tuberculosis complex
P Golby, KA Hatch, J Bacon, R Cooney, P Riley, J Allnutt, J Hinds, ...
Microbiology 153 (10), 3323-3336, 2007
852007
Non-replicating Mycobacterium tuberculosis elicits a reduced infectivity profile with corresponding modifications to the cell wall and extracellular matrix
J Bacon, LJ Alderwick, JA Allnutt, E Gabasova, R Watson, KA Hatch, ...
PloS one 9 (2), e87329, 2014
742014
Time series analysis and mechanistic modelling of heterogeneity and sero-reversion in antibody responses to mild SARS‑CoV-2 infection
C Manisty, TA Treibel, M Jensen, A Semper, G Joy, RK Gupta, ...
EBioMedicine 65, 2021
642021
Mode of action of kanglemycin A, an ansamycin natural product that is active against rifampicin-resistant Mycobacterium tuberculosis
H Mosaei, V Molodtsov, B Kepplinger, J Harbottle, CW Moon, RE Jeeves, ...
Molecular cell 72 (2), 263-274. e5, 2018
572018
Selection of novel TB vaccine candidates and their evaluation as DNA vaccines against aerosol challenge
J Vipond, R Vipond, E Allen-Vercoe, SO Clark, GJ Hatch, KE Gooch, ...
Vaccine 24 (37-39), 6340-6350, 2006
502006
A flow cytometry method for rapidly assessing Mycobacterium tuberculosis responses to antibiotics with different modes of action
CL Hendon-Dunn, KS Doris, SR Thomas, JC Allnutt, AAN Marriott, ...
Antimicrobial agents and chemotherapy 60 (7), 3869-3883, 2016
472016
Mycobacterium tuberculosis Is Resistant to Isoniazid at a Slow Growth Rate by Single Nucleotide Polymorphisms in katG Codon Ser315
RE Jeeves, AAN Marriott, ST Pullan, KA Hatch, JC Allnutt, I Freire-Martin, ...
PloS one 10 (9), e0138253, 2015
452015
Quantification of global transcription patterns in prokaryotes using spotted microarrays
B Sidders, M Withers, SL Kendall, J Bacon, SJ Waddell, J Hinds, P Golby, ...
Genome Biology 8, 1-13, 2007
412007
An assay to compare the infectivity of Mycobacterium tuberculosis isolates based on aerosol infection of guinea pigs and assessment of bacteriology
A Williams, BW James, J Bacon, KA Hatch, GJ Hatch, GA Hall, PD Marsh
Tuberculosis 85 (3), 177-184, 2005
332005
Enhanced heterogeneity of rpoB in Mycobacterium tuberculosis found at low pH
C Jenkins, J Bacon, J Allnutt, KA Hatch, A Bose, DM O'Sullivan, C Arnold, ...
Journal of antimicrobial chemotherapy 63 (6), 1118-1120, 2009
292009
Transcriptional responses of Mycobacterium tuberculosis exposed to adverse conditions in vitro
J Bacon, PD Marsh
Current molecular medicine 7 (3), 277-286, 2007
272007
Mycobacterial antigens expressed under low oxygen tension
BW James, J Bacon, P Marsh
US Patent 7,393,539, 2008
262008
The effect of growth rate on pyrazinamide activity in Mycobacterium tuberculosis - insights for early bactericidal activity?
ST Pullan, JC Allnutt, R Devine, KA Hatch, RE Jeeves, CL Hendon-Dunn, ...
BMC Infectious Diseases 16, 1-11, 2016
192016
Utilisation of the Prestwick Chemical Library to identify drugs that inhibit the growth of mycobacteria
P Kanvatirth, RE Jeeves, J Bacon, GS Besra, LJ Alderwick
PLoS One 14 (3), e0213713, 2019
162019
Noncytotoxic Pyrrolobenzodiazepine–Ciprofloxacin Conjugate with Activity against Mycobacterium tuberculosis
P Picconi, R Jeeves, CW Moon, S Jamshidi, KS Nahar, M Laws, J Bacon, ...
ACS omega 4 (25), 20873-20881, 2019
132019
Hazard Group 3 agent decontamination using hydrogen peroxide vapour in a class III microbiological safety cabinet
T Pottage, S Lewis, A Lansley, S Fraser, C Hendon‐Dunn, J Bacon, ...
Journal of applied microbiology 128 (1), 116-123, 2020
122020
In vitro gene expression dissected: chemostat surgery for Mycobacterium tuberculosis
BW James, J Bacon, T Hampshire, K Morley, PD Marsh
Comparative and functional genomics 3 (4), 345-347, 2002
122002
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