Proteome Integral Solubility Alteration: A High-Throughput Proteomics Assay for Target Deconvolution M Gaetani, P Sabatier, AA Saei, CM Beusch, Z Yang, SL Lundström, ... Journal of proteome research 18 (11), 4027-4037, 2019 | 169 | 2019 |
Comprehensive chemical proteomics for target deconvolution of the redox active drug auranofin AA Saei, H Gullberg, P Sabatier, CM Beusch, K Johansson, B Lundgren, ... Redox biology 32, 101491, 2020 | 67 | 2020 |
ProTargetMiner as a proteome signature library of anticancer molecules for functional discovery AA Saei, CM Beusch, A Chernobrovkin, P Sabatier, B Zhang, ÜG Tokat, ... Nature communications 10 (1), 5715, 2019 | 61 | 2019 |
System-wide identification and prioritization of enzyme substrates by thermal analysis AA Saei, CM Beusch, P Sabatier, JA Wells, H Gharibi, Z Meng, ... Nature communications 12 (1), 1296, 2021 | 54* | 2021 |
Quantitative selection analysis of bacteriophage φCbK susceptibility in Caulobacter crescentus M Christen, C Beusch, Y Bösch, D Cerletti, CE Flores-Tinoco, ... Journal of molecular biology 428 (2), 419-430, 2016 | 46 | 2016 |
A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis Y He, C Ge, À Moreno-Giró, B Xu, CM Beusch, K Sandor, J Su, L Cheng, ... Nature communications 14 (1), 691, 2023 | 27 | 2023 |
Comprehensive chemical proteomics analyses reveal that the new TRi-1 and TRi-2 compounds are more specific thioredoxin reductase 1 inhibitors than auranofin P Sabatier, CM Beusch, R Gencheva, Q Cheng, R Zubarev, ESJ Arnér Redox Biology 48, 102184, 2021 | 25 | 2021 |
An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation P Sabatier, CM Beusch, AA Saei, M Aoun, N Moruzzi, A Coelho, N Leijten, ... Nature communications 12 (1), 6558, 2021 | 19 | 2021 |
Ion-based proteome-integrated solubility alteration assays for systemwide profiling of protein–molecule interactions CM Beusch, P Sabatier, RA Zubarev Analytical Chemistry 94 (19), 7066-7074, 2022 | 17 | 2022 |
GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics SC Wright, A Motso, S Koutsilieri, CM Beusch, P Sabatier, A Berghella, ... Nature communications 14 (1), 6243, 2023 | 10 | 2023 |
System-wide profiling by proteome integral solubility alteration assay of drug residence times for target characterization P Sabatier, CM Beusch, Z Meng, RA Zubarev Analytical Chemistry 94 (45), 15772-15780, 2022 | 6 | 2022 |
Antigen-presenting autoreactive B cells activate regulatory T cells and suppress autoimmune arthritis in mice M Aoun, A Coelho, A Krämer, A Saxena, P Sabatier, CM Beusch, ... Journal of Experimental Medicine 220 (11), e20230101, 2023 | 5 | 2023 |
Ultralight ultrafast enzymes X Zhang, Z Meng, C Beusch, H Gharibi, Q Cheng, L Stefano, J Wang, ... | 4 | 2021 |
Wnt/β-catenin and NFκB signaling synergize to trigger growth-factor-free regeneration of adult primary human hepatocytes N Oliva-Vilarnau, CM Beusch, P Sabatier, E Sakaraki, A Tjaden, L Graetz, ... Hepatology, 10.1097, 2023 | 3 | 2023 |
SIESTA as a universal unbiased proteomics approach for identification and prioritization of enzyme substrates AA Saei, CM Beusch, P Sabatier, JA Wells, H Gharibi, Z Meng, ... | 3 | 2021 |
Therapy targeting antigen-specific T cells by a peptide-based tolerizing vaccine against autoimmune arthritis V Urbonaviciute, L Romero-Castillo, B Xu, H Luo, N Schneider, S Weisse, ... Proceedings of the National Academy of Sciences 120 (25), e2218668120, 2023 | 2 | 2023 |
Ultralight Ultrafast Enzymes X Zhang, Z Meng, CM Beusch, H Gharibi, Q Cheng, H Lyu, L Di Stefano, ... Angewandte Chemie 136 (3), e202316488, 2024 | 1 | 2024 |
Analysis of local extracellular matrix identifies different aetiologies behind bicuspid and tricuspid aortic valve degeneration and suggests therapies CM Beusch, OE Simonson, JO Wedin, P Sabatier, U Felldin, S Kadekar, ... Cellular and Molecular Life Sciences 80 (9), 268, 2023 | 1 | 2023 |
Do light eaters live shorter lives? The case of ultralight Caenorhabditis elegans X Zhang, H Gharibi, CM Beusch, Z Meng, A Saei Dibavar, M Gaetani, ... bioRxiv, 2024.02. 13.580069, 2024 | | 2024 |
Method and Apparatus for Analysing Samples of Biomolecules Using Mass Spectrometry with Data-Independent Acquisition R Zubarev, C Beusch US Patent App. 17/673,409, 2022 | | 2022 |