Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion A Orimo, PB Gupta, DC Sgroi, F Arenzana-Seisdedos, T Delaunay, ... Cell 121 (3), 335-348, 2005 | 4348 | 2005 |
Stromal fibroblasts in cancer: a novel tumor-promoting cell type A Orimo, RA Weinberg Cell cycle 5 (15), 1597-1601, 2006 | 985 | 2006 |
Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts Y Kojima, A Acar, EN Eaton, KT Mellody, C Scheel, I Ben-Porath, ... Proceedings of the National Academy of Sciences 107 (46), 20009-20014, 2010 | 884 | 2010 |
The complete primary structure of human estrogen receptor β (hERβ) and its Heterodimerization with ER αin Vivoandin vitro S Ogawa, S Inoue, T Watanabe, H Hiroi, A Orimo, T Hosoi, Y Ouchi, ... Biochemical and biophysical research communications 243 (1), 122-126, 1998 | 717 | 1998 |
Estrogen activates telomerase S Kyo, M Takakura, T Kanaya, W Zhuo, K Fujimoto, Y Nishio, A Orimo, ... Cancer research 59 (23), 5917-5921, 1999 | 700 | 1999 |
Molecular cloning and characterization of human estrogen receptor βcx: a potential inhibitor of estrogen action in human S Ogawa, S Inoue, T Watanabe, A Orimo, T Hosoi, Y Ouchi, M Muramatsu Nucleic acids research 26 (15), 3505-3512, 1998 | 605 | 1998 |
Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression M Shimoda, KT Mellody, A Orimo Seminars in cell & developmental biology 21 (1), 19-25, 2010 | 419 | 2010 |
Agonistic effect of tamoxifen is dependent on cell type, ERE-promoter context, and estrogen receptor subtype: functional difference between estrogen receptors α and β T Watanabe, S Inoue, S Ogawa, Y Ishii, H Hiroi, K Ikeda, A Orimo, ... Biochemical and biophysical research communications 236 (1), 140-145, 1997 | 291 | 1997 |
Differential interactions of bisphenol A and17β-estradiol with estrogen receptor α (ERα) and ERβ H HIROI, O TSUTSUMI, M MOMOEDA, Y TAKAI, Y OSUGA, Y TAKETANI Endocrine journal 46 (6), 773-778, 1999 | 265 | 1999 |
Carcinoma‐associated fibroblasts: non‐neoplastic tumour‐promoting mesenchymal cells UM Polanska, A Orimo Journal of cellular physiology 228 (8), 1651-1657, 2013 | 248 | 2013 |
UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells A Okuda, A Fukushima, M Nishimoto, A Orimo, T Yamagishi, ... The EMBO journal 17 (7), 2019-2032, 1998 | 223 | 1998 |
Differential immunolocalization of estrogen receptor alpha and beta in rat ovary and uterus H Hiroi, S Inoue, T Watanabe, W Goto, A Orimo, M Momoeda, O Tsutsumi, ... Journal of Molecular Endocrinology 22 (1), 37-44, 1999 | 212 | 1999 |
Genomic binding-site cloning reveals an estrogen-responsive gene that encodes a RING finger protein. S Inoue, A Orimo, T Hosoi, S Kondo, H Toyoshima, T Kondo, A Ikegami, ... Proceedings of the National Academy of Sciences 90 (23), 11117-11121, 1993 | 210 | 1993 |
Isolation of estrogen-responsive genes with a CpG island library T Watanabe, S Inoue, H Hiroi, A Orimo, H Kawashima, M Muramatsu Molecular and cellular biology 18 (1), 442-449, 1998 | 185 | 1998 |
Vascular smooth muscle cells as target for estrogen A Orimo, S Inoue, A Ikegami, T Hosoi, M Akishita, Y Ouchi, M Muramatsu, ... Biochemical and biophysical research communications 195 (2), 730-736, 1993 | 181 | 1993 |
Carcinoma-associated fibroblasts are a promising therapeutic target S Togo, UM Polanska, Y Horimoto, A Orimo Cancers 5 (1), 149-169, 2013 | 180 | 2013 |
Heterogeneity of stromal fibroblasts in tumor A Orimo, RA Weinberg Cancer biology & therapy 6 (4), 618-619, 2007 | 179 | 2007 |
Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling P Roswall, M Bocci, M Bartoschek, H Li, G Kristiansen, S Jansson, S Lehn, ... Nature medicine 24 (4), 463-473, 2018 | 156 | 2018 |
The roles of tumor-and metastasis-promoting carcinoma-associated fibroblasts in human carcinomas Y Mezawa, A Orimo Cell and tissue research 365, 675-689, 2016 | 126 | 2016 |
Cancer-associated myofibroblasts possess various factors to promote endometrial tumor progression A Orimo, Y Tomioka, Y Shimizu, M Sato, S Oigawa, K Kamata, Y Nogi, ... Clinical cancer research 7 (10), 3097-3105, 2001 | 126 | 2001 |