CaMKII is a RIP3 substrate mediating ischemia-and oxidative stress–induced myocardial necroptosis T Zhang, Y Zhang, M Cui, LI Jin, Y Wang, F Lv, Y Liu, W Zheng, H Shang, ... Nature medicine 22 (2), 175-182, 2016 | 682 | 2016 |
Inducible nitric oxide synthase deficiency protects the heart from systolic overload–induced ventricular hypertrophy and congestive heart failure P Zhang, X Xu, X Hu, ED Van Deel, G Zhu, Y Chen Circulation research 100 (7), 1089-1098, 2007 | 268 | 2007 |
PGC-1α regulates expression of myocardial mitochondrial antioxidants and myocardial oxidative stress after chronic systolic overload Z Lu, X Xu, X Hu, J Fassett, G Zhu, Y Tao, J Li, Y Huang, P Zhang, B Zhao, ... Antioxidants & redox signaling 13 (7), 1011-1022, 2010 | 239 | 2010 |
AMP activated protein kinase-α2 deficiency exacerbates pressure-overload–induced left ventricular hypertrophy and dysfunction in mice P Zhang, X Hu, X Xu, J Fassett, G Zhu, B Viollet, W Xu, B Wiczer, ... Hypertension 52 (5), 918-924, 2008 | 200 | 2008 |
Oxidative stress regulates left ventricular PDE5 expression in the failing heart Z Lu, X Xu, X Hu, S Lee, JH Traverse, G Zhu, J Fassett, Y Tao, P Zhang, ... Circulation 121 (13), 1474-1483, 2010 | 198 | 2010 |
Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing LN Wei, X Hu, D Chandra, E Seto, M Farooqui Journal of Biological Chemistry 275 (52), 40782-40787, 2000 | 183 | 2000 |
Left ventricular failure produces profound lung remodeling and pulmonary hypertension in mice: heart failure causes severe lung disease Y Chen, H Guo, D Xu, X Xu, H Wang, X Hu, Z Lu, D Kwak, Y Xu, ... hypertension 59 (6), 1170-1178, 2012 | 164 | 2012 |
Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine X Hu, D Atzler, X Xu, P Zhang, H Guo, Z Lu, J Fassett, E Schwedhelm, ... Arteriosclerosis, thrombosis, and vascular biology 31 (7), 1540-1546, 2011 | 148 | 2011 |
Upregulation of MG53 induces diabetic cardiomyopathy through transcriptional activation of peroxisome proliferation-activated receptor α F Liu, R Song, Y Feng, J Guo, Y Chen, Y Zhang, T Chen, Y Wang, ... Circulation 131 (9), 795-804, 2015 | 145 | 2015 |
Extracellular superoxide dismutase protects the heart against oxidative stress and hypertrophy after myocardial infarction ED van Deel, Z Lu, X Xu, G Zhu, X Hu, TD Oury, RJ Bache, DJ Duncker, ... Free Radical Biology and Medicine 44 (7), 1305-1313, 2008 | 140 | 2008 |
Extracellular superoxide dismutase deficiency exacerbates pressure overload–induced left ventricular hypertrophy and dysfunction Z Lu, X Xu, X Hu, G Zhu, P Zhang, ED Van Deel, JP French, JT Fassett, ... Hypertension 51 (1), 19-25, 2008 | 115 | 2008 |
Xanthine oxidase inhibition with febuxostat attenuates systolic overload-induced left ventricular hypertrophy and dysfunction in mice X Xu, X Hu, Z Lu, P Zhang, L Zhao, JL Wessale, RJ Bache, Y Chen Journal of cardiac failure 14 (9), 746-753, 2008 | 107 | 2008 |
Endoplasmic reticulum stress sensor protein kinase R–Like endoplasmic reticulum kinase (PERK) protects against pressure overload–induced heart failure and lung remodeling X Liu, D Kwak, Z Lu, X Xu, J Fassett, H Wang, Y Wei, DR Cavener, X Hu, ... Hypertension 64 (4), 738-744, 2014 | 98 | 2014 |
Vascular endothelial-specific dimethylarginine dimethylaminohydrolase-1–deficient mice reveal that vascular endothelium plays an important role in removing asymmetric … X Hu, X Xu, G Zhu, D Atzler, M Kimoto, J Chen, E Schwedhelm, ... Circulation 120 (22), 2222-2229, 2009 | 95 | 2009 |
AMP activated protein kinase-α2 regulates expression of estrogen-related receptor-α, a metabolic transcription factor related to heart failure development X Hu, X Xu, Z Lu, P Zhang, J Fassett, Y Zhang, Y Xin, JL Hall, B Viollet, ... Hypertension 58 (4), 696-703, 2011 | 90 | 2011 |
Glucose-sensitive myokine/cardiokine MG53 regulates systemic insulin response and metabolic homeostasis HK Wu, Y Zhang, CM Cao, X Hu, M Fang, Y Yao, L Jin, G Chen, P Jiang, ... Circulation 139 (7), 901-914, 2019 | 89 | 2019 |
Metformin Protects Against Systolic Overload–Induced Heart Failure Independent of AMP-Activated Protein Kinase α2 X Xu, Z Lu, J Fassett, P Zhang, X Hu, X Liu, D Kwak, J Li, G Zhu, Y Tao, ... Hypertension 63 (4), 723-728, 2014 | 85 | 2014 |
Exacerbated pulmonary arterial hypertension and right ventricular hypertrophy in animals with loss of function of extracellular superoxide dismutase D Xu, H Guo, X Xu, Z Lu, J Fassett, X Hu, Y Xu, Q Tang, D Hu, A Somani, ... Hypertension 58 (2), 303-309, 2011 | 82 | 2011 |
NDUFAB1 confers cardio-protection by enhancing mitochondrial bioenergetics through coordination of respiratory complex and supercomplex assembly T Hou, R Zhang, C Jian, W Ding, Y Wang, S Ling, Q Ma, X Hu, H Cheng, ... Cell research 29 (9), 754-766, 2019 | 74 | 2019 |
Negative regulation of AMPK signaling by high glucose via E3 ubiquitin ligase MG53 P Jiang, L Ren, L Zhi, Z Yu, F Lv, F Xu, W Peng, X Bai, K Cheng, L Quan, ... Molecular cell 81 (3), 629-637. e5, 2021 | 73 | 2021 |