| Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2 X Deng, N Dzamko, A Prescott, P Davies, Q Liu, Q Yang, JD Lee, ... Nature chemical biology 7 (4), 203-205, 2011 | 468 | 2011 |
| Functional interrogation of the kinome using nucleotide acyl phosphates MP Patricelli, AK Szardenings, M Liyanage, TK Nomanbhoy, M Wu, ... Biochemistry 46 (2), 350-358, 2007 | 464 | 2007 |
| Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation CM Olson, B Jiang, MA Erb, Y Liang, ZM Doctor, Z Zhang, T Zhang, ... Nature chemical biology 14 (2), 163-170, 2018 | 427 | 2018 |
| Discovery of potent and selective covalent inhibitors of JNK T Zhang, F Inesta-Vaquera, M Niepel, J Zhang, SB Ficarro, T Machleidt, ... Chemistry & biology 19 (1), 140-154, 2012 | 353 | 2012 |
| In situ kinase profiling reveals functionally relevant properties of native kinases MP Patricelli, TK Nomanbhoy, J Wu, H Brown, D Zhou, J Zhang, ... Chemistry & biology 18 (6), 699-710, 2011 | 346 | 2011 |
| Mechanistic and pharmacological characterization of PF-04457845: a highly potent and selective fatty acid amide hydrolase inhibitor that reduces inflammatory and … K Ahn, SE Smith, MB Liimatta, D Beidler, N Sadagopan, DT Dudley, ... Journal of Pharmacology and Experimental Therapeutics 338 (1), 114-124, 2011 | 244 | 2011 |
| Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity K Ahn, DS Johnson, LR Fitzgerald, M Liimatta, A Arendse, T Stevenson, ... Biochemistry 46 (45), 13019-13030, 2007 | 240 | 2007 |
| C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases YQ Gosser, TK Nomanbhoy, B Aghazadeh, D Manor, C Combs, ... Nature 387 (6635), 814-819, 1997 | 235 | 1997 |
| Discovery of PF-04457845: a highly potent, orally bioavailable, and selective urea FAAH inhibitor DS Johnson, C Stiff, SE Lazerwith, SR Kesten, LK Fay, M Morris, ... ACS medicinal chemistry letters 2 (2), 91-96, 2011 | 192 | 2011 |
| Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein JA Glaven, IP Whitehead, T Nomanbhoy, R Kay, RA Cerione Journal of Biological Chemistry 271 (44), 27374-27381, 1996 | 162 | 1996 |
| Characterization of the Interaction between RhoGDI and Cdc42Hs Using Fluorescence Spectroscopy (∗) TK Nomanbhoy, RA Cerione Journal of Biological Chemistry 271 (17), 10004-10009, 1996 | 147 | 1996 |
| Transfer RNA–Dependent Translocation of Misactivated Amino Acids to Prevent Errors in Protein Synthesis TK Nomanbhoy, TL Hendrickson, P Schimmel Molecular cell 4 (4), 519-528, 1999 | 106 | 1999 |
| ERK5 kinase activity is dispensable for cellular immune response and proliferation ECK Lin, CM Amantea, TK Nomanbhoy, H Weissig, J Ishiyama, Y Hu, ... Proceedings of the National Academy of Sciences 113 (42), 11865-11870, 2016 | 96 | 2016 |
| Synthesis and Structure–activity Relationship of N-alkyl Gly-boro-Pro Inhibitors of DPP4, FAP, and DPP7 Y Hu, L Ma, M Wu, MS Wong, B Li, S Corral, Z Yu, T Nomanbhoy, ... Bioorganic & Medicinal Chemistry Letters 15 (19), 4239-4242, 2005 | 92 | 2005 |
| Mutational separation of two pathways for editing by a class I tRNA synthetase TL Hendrickson, TK Nomanbhoy, V de Crécy-Lagard, S Fukai, O Nureki, ... Molecular cell 9 (2), 353-362, 2002 | 90 | 2002 |
| Kinetics of Cdc42 membrane extraction by Rho-GDI monitored by real-time fluorescence resonance energy transfer TK Nomanbhoy, JW Erickson, RA Cerione Biochemistry 38 (6), 1744-1750, 1999 | 88 | 1999 |
| Benzothiophene piperazine and piperidine urea inhibitors of fatty acid amide hydrolase (FAAH) DS Johnson, K Ahn, S Kesten, SE Lazerwith, Y Song, M Morris, L Fay, ... Bioorganic & medicinal chemistry letters 19 (10), 2865-2869, 2009 | 82 | 2009 |
| Discovery of type II inhibitors of TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2) L Tan, T Nomanbhoy, D Gurbani, M Patricelli, J Hunter, J Geng, ... Journal of medicinal chemistry 58 (1), 183-196, 2015 | 81 | 2015 |
| Blocking site-to-site translocation of a misactivated amino acid by mutation of a class I tRNA synthetase AC Bishop, TK Nomanbhoy, P Schimmel Proceedings of the National Academy of Sciences 99 (2), 585-590, 2002 | 77 | 2002 |
| Errors from selective disruption of the editing center in a tRNA synthetase TL Hendrickson, TK Nomanbhoy, P Schimmel Biochemistry 39 (28), 8180-8186, 2000 | 67 | 2000 |
