Organoid cultures derived from patients with advanced prostate cancer D Gao, I Vela, A Sboner, PJ Iaquinta, WR Karthaus, A Gopalan, ... Cell 159 (1), 176-187, 2014 | 1455 | 2014 |
SOX2 promotes lineage plasticity and antiandrogen resistance in TP53-and RB1-deficient prostate cancer P Mu, Z Zhang, M Benelli, WR Karthaus, E Hoover, CC Chen, ... Science 355 (6320), 84-88, 2017 | 885 | 2017 |
PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors W Lee, S Teckie, T Wiesner, L Ran, CN Prieto Granada, M Lin, S Zhu, ... Nature genetics 46 (11), 1227-1232, 2014 | 531 | 2014 |
Clathrin and phosphatidylinositol-4, 5-bisphosphate regulate autophagic lysosome reformation Y Rong, M Liu, L Ma, W Du, H Zhang, Y Tian, Z Cao, Y Li, H Ren, C Zhang, ... Nature cell biology 14 (9), 924-934, 2012 | 306 | 2012 |
Alternative transcription initiation leads to expression of a novel ALK isoform in cancer T Wiesner, W Lee, AC Obenauf, L Ran, R Murali, QF Zhang, EWP Wong, ... Nature 526 (7573), 453-457, 2015 | 237 | 2015 |
Combined inhibition of MAP kinase and KIT signaling synergistically destabilizes ETV1 and suppresses GIST tumor growth L Ran, I Sirota, Z Cao, D Murphy, Y Chen, S Shukla, Y Xie, MC Kaufmann, ... Cancer discovery 5 (3), 304-315, 2015 | 128 | 2015 |
Loss of CHD1 promotes heterogeneous mechanisms of resistance to AR-targeted therapy via chromatin dysregulation Z Zhang, C Zhou, X Li, SD Barnes, S Deng, E Hoover, CC Chen, YS Lee, ... Cancer cell 37 (4), 584-598. e11, 2020 | 108 | 2020 |
The cell cycle restricts activation-induced cytidine deaminase activity to early G1 Q Wang, KR Kieffer-Kwon, TY Oliveira, CT Mayer, K Yao, J Pai, Z Cao, ... Journal of Experimental Medicine 214 (1), 49-58, 2017 | 85 | 2017 |
Aberrant activation of a gastrointestinal transcriptional circuit in prostate cancer mediates castration resistance S Shukla, J Cyrta, DA Murphy, EG Walczak, L Ran, P Agrawal, Y Xie, ... Cancer cell 32 (6), 792-806. e7, 2017 | 74 | 2017 |
Lineage reversion drives WNT independence in intestinal cancer T Han, S Goswami, Y Hu, F Tang, MP Zafra, C Murphy, Z Cao, JT Poirier, ... Cancer discovery 10 (10), 1590-1609, 2020 | 58 | 2020 |
FOXF1 defines the core-regulatory circuitry in gastrointestinal stromal tumor L Ran, Y Chen, J Sher, EWP Wong, D Murphy, JQ Zhang, D Li, K Deniz, ... Cancer discovery 8 (2), 234-251, 2018 | 57 | 2018 |
Somatic tissue engineering in mouse models reveals an actionable role for WNT pathway alterations in prostate cancer metastasis J Leibold, M Ruscetti, Z Cao, YJ Ho, T Baslan, M Zou, W Abida, J Feucht, ... Cancer discovery 10 (7), 1038-1057, 2020 | 39 | 2020 |
COP1/DET1/ETS axis regulates ERK transcriptome and sensitivity to MAPK inhibitors Y Xie, Z Cao, EWP Wong, Y Guan, W Ma, JQ Zhang, EG Walczak, ... The Journal of clinical investigation 128 (4), 1442-1457, 2018 | 33 | 2018 |
Rapid interrogation of cancer cell of origin through CRISPR editing W Feng, Z Cao, PX Lim, H Zhao, H Luo, N Mao, YS Lee, AA Rivera, ... Proceedings of the National Academy of Sciences 118 (32), e2110344118, 2021 | 17 | 2021 |
ETV1-Positive Cells Give Rise to BRAFV600E-Mutant Gastrointestinal Stromal Tumors L Ran, D Murphy, J Sher, Z Cao, S Wang, E Walczak, Y Guan, Y Xie, ... Cancer research 77 (14), 3758-3765, 2017 | 15 | 2017 |
Lysosome‐dependent FOXA1 ubiquitination contributes to luminal lineage of advanced prostate cancer SI Celada, G Li, LJ Celada, W Lu, T Kanagasabai, W Feng, Z Cao, ... Molecular Oncology 17 (10), 2126-2146, 2023 | 2 | 2023 |
Adenylyl cyclase localization to the uropod of aggregating Dictyostelium cells requires RacC C Wang, D Jung, Z Cao, CY Chung Biochemical and biophysical research communications 465 (3), 613-619, 2015 | 2 | 2015 |
Prostate Cancer Modeling: From Human Cancer Genomic Analysis to Mouse and Organoid Engineering Z Cao Weill Medical College of Cornell University, 2023 | | 2023 |
Abstract NG06: CHD1-loss confers AR targeted therapy resistance via promoting cancer heterogeneity and lineage plasticity Z Zhang, C Zhou, X Li, S Barnes, S Deng, E Hoover, CC Chen, YS Lee, ... Cancer Research 80 (16_Supplement), NG06-NG06, 2020 | | 2020 |
Abstract A074: Aberrant activation of a gastrointestinal transcriptional circuit in prostate cancer mediates castration resistance S Shukla, J Cyrta, D Murphy, E Walczak, L Ran, P Agrawal, Y Xie, Y Chen, ... Cancer Research 78 (16_Supplement), A074-A074, 2018 | | 2018 |