| Recent advances in syntheses of heterocycles and carbocycles via homogeneous gold catalysis. Part 1: Heteroatom addition and hydroarylation reactions of alkynes, allenes, and … HC Shen Tetrahedron 64 (18), 3885-3903, 2008 | 563 | 2008 |
| Recent advances in syntheses of carbocycles and heterocycles via homogeneous gold catalysis. Part 2: Cyclizations and cycloadditions HC Shen Tetrahedron 64 (34), 7847-7870, 2008 | 352 | 2008 |
| Discovery of inhibitors of soluble epoxide hydrolase: a target with multiple potential therapeutic indications HC Shen, BD Hammock Journal of medicinal chemistry 55 (5), 1789-1808, 2012 | 260 | 2012 |
| Ruthenium-catalyzed intramolecular [5+ 2] cycloadditions BM Trost, FD Toste, H Shen Journal of the American Chemical Society 122 (10), 2379-2380, 2000 | 252 | 2000 |
| Synthesis of chiral chromans by the Pd-catalyzed asymmetric allylic alkylation (AAA): Scope, mechanism, and applications BM Trost, HC Shen, L Dong, JP Surivet, C Sylvain Journal of the American Chemical Society 126 (38), 11966-11983, 2004 | 223 | 2004 |
| Asymmetric synthesis of chiral chromans HC Shen Tetrahedron 65 (20), 3931-3952, 2009 | 218 | 2009 |
| Structure-based design and synthesis of potent cyclic peptides inhibiting the YAP–TEAD protein–protein interaction Z Zhang, Z Lin, Z Zhou, HC Shen, SF Yan, AV Mayweg, Z Xu, N Qin, ... ACS medicinal chemistry letters 5 (9), 993-998, 2014 | 151 | 2014 |
| Syntheses of seven‐membered rings: ruthenium‐catalyzed intramolecular [5+ 2] cycloadditions BM Trost, HC Shen, DB Horne, FD Toste, BG Steinmetz, C Koradin Chemistry–A European Journal 11 (8), 2577-2590, 2005 | 136 | 2005 |
| Unusual effects in the Pd-catalyzed asymmetric allylic alkylations: Synthesis of chiral chromans BM Trost, HC Shen, L Dong, JP Surivet Journal of the American Chemical Society 125 (31), 9276-9277, 2003 | 136 | 2003 |
| Heteroaryldihydropyrimidine (HAP) and sulfamoylbenzamide (SBA) inhibit hepatitis B virus replication by different molecular mechanisms Z Zhou, T Hu, X Zhou, S Wildum, F Garcia-Alcalde, Z Xu, D Wu, Y Mao, ... Scientific reports 7 (1), 42374, 2017 | 132 | 2017 |
| Palladium-catalyzed Suzuki− Miyaura coupling of pyridyl-2-boronic esters with aryl halides using highly active and air-stable phosphine chloride and oxide ligands DX Yang, SL Colletti, K Wu, M Song, GY Li, HC Shen Organic letters 11 (2), 381-384, 2009 | 132 | 2009 |
| Constructing Tricyclic Compounds Containing a Seven-Membered Ring by Ruthenium-Catalyzed Intramolecular [5+ 2] Cycloaddition. BM Trost, HC Shen Angewandte Chemie (International ed. in English) 40 (12), 2313-2316, 2001 | 131 | 2001 |
| Biomimetic enantioselective total synthesis of (−)-siccanin via the Pd-catalyzed asymmetric allylic alkylation (AAA) and sequential radical cyclizations BM Trost, HC Shen, JP Surivet Journal of the American Chemical Society 126 (39), 12565-12579, 2004 | 113 | 2004 |
| An Enantioselective Biomimetic Total Synthesis of (−)‐Siccanin BM Trost, HC Shen, JP Surivet Angewandte Chemie 115 (33), 4073-4077, 2003 | 104 | 2003 |
| Sequential 1, 2-Addition− Electrocyclic Ring Closures Involving Acyclic α, β-Unsaturated Iminiums: A Formal [3+ 3] Cycloaddition Strategy to Unique Pyranyl Spirocycles RP Hsung, HC Shen, CJ Douglas, CD Morgan, SJ Degen, LJ Yao The Journal of Organic Chemistry 64 (3), 690-691, 1999 | 104 | 1999 |
| On the regioselectivity of the Ru-catalyzed intramolecular [5+ 2] cycloaddition BM Trost, HC Shen Organic Letters 2 (16), 2523-2525, 2000 | 100 | 2000 |
| Soluble epoxide hydrolase inhibitors: a patent review HC Shen Expert opinion on therapeutic patents 20 (7), 941-956, 2010 | 98 | 2010 |
| Design and synthesis of orally bioavailable 4-methyl heteroaryldihydropyrimidine based hepatitis B virus (HBV) capsid inhibitors Z Qiu, X Lin, M Zhou, Y Liu, W Zhu, W Chen, W Zhang, L Guo, H Liu, G Wu, ... Journal of medicinal chemistry 59 (16), 7651-7666, 2016 | 96 | 2016 |
| Small molecule dysregulation of TEAD lipidation induces a dominant-negative inhibition of hippo pathway signaling JK Holden, JJ Crawford, CL Noland, S Schmidt, JR Zbieg, JA Lacap, ... Cell reports 31 (12), 2020 | 89 | 2020 |
| Gold (I)-catalyzed regioselective cyclizations of silyl ketene amides and carbamates with alkynes EC Minnihan, SL Colletti, FD Toste, HC Shen The Journal of Organic Chemistry 72 (16), 6287-6289, 2007 | 88 | 2007 |
