| Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides BA Yankner, LK Duffy, DA Kirschner Science 250 (4978), 279-282, 1990 | 2768 | 1990 |
| On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants. A Lomakin, DS Chung, GB Benedek, DA Kirschner, DB Teplow Proceedings of the National Academy of Sciences 93 (3), 1125-1129, 1996 | 1027 | 1996 |
| X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation. DA Kirschner, C Abraham, DJ Selkoe Proceedings of the National Academy of Sciences 83 (2), 503-507, 1986 | 740 | 1986 |
| Kinetic theory of fibrillogenesis of amyloid β-protein A Lomakin, DB Teplow, DA Kirschner, GB Benedek Proceedings of the National Academy of Sciences 94 (15), 7942-7947, 1997 | 677 | 1997 |
| Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro. DA Kirschner, H Inouye, LK Duffy, A Sinclair, M Lind, DJ Selkoe Proceedings of the National Academy of Sciences 84 (19), 6953-6957, 1987 | 664 | 1987 |
| pH-dependent structural transitions of Alzheimer amyloid peptides PE Fraser, JT Nguyen, WK Surewicz, DA Kirschner Biophysical journal 60 (5), 1190-1201, 1991 | 469 | 1991 |
| Mice deficient for the glycoprotein show subtle abnormalities in myelin D Montag, KP Giese, U Bartsch, R Martini, Y Lang, H Blüthmann, ... Neuron 13 (1), 229-246, 1994 | 448 | 1994 |
| Constitutively active Akt induces enhanced myelination in the CNS AI Flores, SP Narayanan, EN Morse, HE Shick, X Yin, G Kidd, RL Avila, ... Journal of Neuroscience 28 (28), 7174-7183, 2008 | 398 | 2008 |
| Molecular determinants of amyloid deposition in Alzheimer's disease: conformational studies of synthetic. beta.-protein fragments K Halverson, PE Fraser, DA Kirschner, PT Lansbury Jr Biochemistry 29 (11), 2639-2644, 1990 | 384 | 1990 |
| Structure of beta-crystallite assemblies formed by Alzheimer beta-amyloid protein analogues: analysis by x-ray diffraction H Inouye, PE Fraser, DA Kirschner Biophysical journal 64 (2), 502-519, 1993 | 370 | 1993 |
| Fibril formation by primate, rodent, and Dutch-hemorrhagic analogs of Alzheimer amyloid. beta.-protein PE Fraser, JT Nguyen, H Inouye, WK Surewicz, DJ Selkoe, MB Podlisny, ... Biochemistry 31 (44), 10716-10723, 1992 | 347 | 1992 |
| Structural analysis of Alzheimer's β (1–40) amyloid: protofilament assembly of tubular fibrils SB Malinchik, H Inouye, KE Szumowski, DA Kirschner Biophysical journal 74 (1), 537-545, 1998 | 328 | 1998 |
| Myelin membrane structure at 10 Ċ resolution DLD Caspar, DA KIRSCHNER Nature new biology 231 (2), 46-52, 1971 | 309 | 1971 |
| Effects of sulfate ions on Alzheimer β/A4 peptide assemblies: implications for amyloid fibril‐proteoglycan interactions PE Fraser, JT Nguyen, DT Chin, DA Kirschner Journal of neurochemistry 59 (4), 1531-1540, 1992 | 288 | 1992 |
| Compact myelin exists in the absence of basic protein in the shiverer mutant mouse DA Kirschner, AL Ganser Nature 283 (5743), 207-210, 1980 | 271 | 1980 |
| The formation of straight and twisted filaments from short tau peptides WJ Goux, L Kopplin, AD Nguyen, K Leak, M Rutkofsky, ... Journal of Biological Chemistry 279 (26), 26868-26875, 2004 | 248 | 2004 |
| Water diffusion, T2, and compartmentation in frog sciatic nerve S Peled, DG Cory, SA Raymond, DA Kirschner, FA Jolesz Magnetic Resonance in Medicine: An Official Journal of the International …, 1999 | 228 | 1999 |
| X-ray diffraction of scrapie prion rods and PrP peptides JT Nguyen, H Inouye, MA Baldwin, RJ Fletterick, FE Cohen, SB Prusiner, ... Journal of molecular biology 252 (4), 412-422, 1995 | 210 | 1995 |
| Conformation and fibrillogenesis of Alzheimer Aβ peptides with selected substitution of charged residues PE Fraser, DR McLachlan, WK Surewicz, CA Mizzen, AD Snow, ... Journal of molecular biology 244 (1), 64-73, 1994 | 207 | 1994 |
| α1‐Antichymotrypsin Binding to Alzheimer Aβ Peptides Is Sequence Specific and Induces Fibril Disaggregation In Vitro PE Fraser, JT Nguyen, DR McLachlan, CR Abraham, DA Kirschner Journal of neurochemistry 61 (1), 298-305, 1993 | 186 | 1993 |
