| Variants in CPA1 are strongly associated with early onset chronic pancreatitis H Witt, S Beer, J Rosendahl, JM Chen, GR Chandak, A Masamune, ... Nature genetics 45 (10), 1216-1220, 2013 | 327 | 2013 |
| Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk S Beer, J Zhou, A Szabó, S Keiles, GR Chandak, H Witt, M Sahin-Tóth Gut 62 (11), 1616-1624, 2013 | 117 | 2013 |
| Increased activation of hereditary pancreatitis-associated human cationic trypsinogen mutants in presence of chymotrypsin C A Szabó, M Sahin-Tóth Journal of Biological Chemistry 287 (24), 20701-20710, 2012 | 107 | 2012 |
| Protease-sensitive pancreatic lipase variants are associated with early onset chronic pancreatitis D Lasher, A Szabó, A Masamune, JM Chen, X Xiao, DC Whitcomb, ... Official journal of the American College of Gastroenterology| ACG 114 (6 …, 2019 | 61 | 2019 |
| Determinants of chymotrypsin C cleavage specificity in the calcium‐binding loop of human cationic trypsinogen A Szabó, M Sahin‐Tóth The FEBS journal 279 (23), 4283-4292, 2012 | 58 | 2012 |
| The effects of organic solvent/water mixtures on the structure and catalytic activity of porcine pepsin LM Simon, M Kotormán, A Szabó, J Nemcsók, I Laczkó Process Biochemistry 42 (5), 909-912, 2007 | 49 | 2007 |
| Chymotrypsin C is a co-activator of human pancreatic procarboxypeptidases A1 and A2 R Szmola, M Bence, A Carpentieri, A Szabó, CE Costello, J Samuelson, ... Journal of biological chemistry 286 (3), 1819-1827, 2011 | 45 | 2011 |
| Improved stability and catalytic activity of chemically modified papain in aqueous organic solvents A Szabó, M Kotormán, I Laczkó, LM Simon Process Biochemistry 44 (2), 199-204, 2009 | 41 | 2009 |
| Effects of Ca2+ on catalytic activity and conformation of trypsin and α-chymotrypsin in aqueous ethanol M Kotormán, I Laczkó, A Szabó, LM Simon Biochemical and biophysical research communications 304 (1), 18-21, 2003 | 41 | 2003 |
| Long-range electrostatic complementarity governs substrate recognition by human chymotrypsin C, a key regulator of digestive enzyme activation J Batra, A Szabó, TR Caulfield, AS Soares, M Sahin-Toth, ES Radisky Journal of Biological Chemistry 288 (14), 9848-9859, 2013 | 40 | 2013 |
| Spectroscopic studies of stability of papain in aqueous organic solvents A Szabó, M Kotormán, I Laczkó, LM Simon Journal of Molecular Catalysis B: Enzymatic 41 (1-2), 43-48, 2006 | 38 | 2006 |
| High affinity small protein inhibitors of human chymotrypsin C (CTRC) selected by phage display reveal unusual preference for P4′ acidic residues A Szabó, D Héja, D Szakács, K Zboray, KA Kékesi, ES Radisky, ... Journal of Biological Chemistry 286 (25), 22535-22545, 2011 | 36 | 2011 |
| A novel mutation in PNLIP causes pancreatic triglyceride lipase deficiency through protein misfolding A Szabó, X Xiao, M Haughney, A Spector, M Sahin-Tóth, ME Lowe Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (7 …, 2015 | 32 | 2015 |
| CELA2A mutations predispose to early-onset atherosclerosis and metabolic syndrome and affect plasma insulin and platelet activation F Esteghamat, JS Broughton, E Smith, R Cardone, T Tyagi, M Guerra, ... Nature genetics 51 (8), 1233-1243, 2019 | 29 | 2019 |
| Effects of polyethylene glycol on stability of α-chymotrypsin in aqueous ethanol solvent LM Simon, M Kotorman, A Szabo, G Garab, I Laczko Biochemical and biophysical research communications 317 (2), 610-613, 2004 | 29 | 2004 |
| Complex formation of human proelastases with procarboxypeptidases A1 and A2 A Szabó, C Pilsak, M Bence, H Witt, M Sahin-Tóth Journal of Biological Chemistry 291 (34), 17706-17716, 2016 | 28 | 2016 |
| Mesotrypsin signature mutation in a chymotrypsin C (CTRC) variant associated with chronic pancreatitis A Szabó, M Ludwig, E Hegyi, R Szépeová, H Witt, M Sahin-Tóth Journal of Biological Chemistry 290 (28), 17282-17292, 2015 | 28 | 2015 |
| Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis A Szabó, V Toldi, LD Gazda, A Demcsák, J Tőzsér, M Sahin-Tóth Journal of Biological Chemistry 296, 2021 | 23 | 2021 |
| Detection of human elastase isoforms by the ScheBo Pancreatic Elastase 1 Test AZ Tóth, A Szabó, E Hegyi, P Hegyi, M Sahin-Tóth American Journal of Physiology-Gastrointestinal and Liver Physiology 312 (6 …, 2017 | 23 | 2017 |
| Overlapping specificity of duplicated human pancreatic elastase 3 isoforms and archetypal porcine elastase 1 provides clues to evolution of digestive enzymes E Boros, A Szabó, K Zboray, D Héja, G Pál, M Sahin-Tóth Journal of Biological Chemistry 292 (7), 2690-2702, 2017 | 16 | 2017 |
