Gianluca Bossi
Gianluca Bossi
Istituto Nazionale Tumori Regina Elena
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Mutant p53 gain of function: reduction of tumor malignancy of human cancer cell lines through abrogation of mutant p53 expression
G Bossi, E Lapi, S Strano, C Rinaldo, G Blandino, A Sacchi
Oncogene 25 (2), 304-309, 2006
Interference with p53 protein inhibits hematopoietic and muscle differentiation.
S Soddu, G Blandino, R Scardigli, S Coen, A Marchetti, MG Rizzo, ...
The Journal of cell biology 134 (1), 193-204, 1996
Evidences that leptin up-regulates E-cadherin expression in breast cancer: effects on tumor growth and progression
L Mauro, S Catalano, G Bossi, M Pellegrino, I Barone, S Morales, ...
Cancer research 67 (7), 3412-3421, 2007
Leptin mediates tumor–stromal interactions that promote the invasive growth of breast cancer cells
I Barone, S Catalano, L Gelsomino, S Marsico, C Giordano, S Panza, ...
Cancer research 72 (6), 1416-1427, 2012
MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma
F Marampon, G Bossi, C Ciccarelli, A Di Rocco, A Sacchi, RG Pestell, ...
Molecular cancer therapeutics 8 (3), 543-551, 2009
A meta-analysis of the abscopal effect in preclinical models: Is the biologically effective dose a relevant physical trigger?
R Marconi, S Strolin, G Bossi, L Strigari
PloS one 12 (2), e0171559, 2017
Restoration of wild‐type p53 function in human cancer: Relevance for tumor therapy
G Bossi, A Sacchi
Head & neck 29 (3), 272-284, 2007
Insights of crosstalk between p53 protein and the MKK3/MKK6/p38 MAPK signaling pathway in cancer
L Stramucci, A Pranteda, G Bossi
Cancers 10 (5), 131, 2018
Mutant p53-induced up-regulation of mitogen-activated protein kinase kinase 3 contributes to gain of function
A Gurtner, G Starace, G Norelli, G Piaggio, A Sacchi, G Bossi
Journal of Biological Chemistry 285 (19), 14160-14169, 2010
Conditional RNA interference in vivo to study mutant p53 oncogenic gain of function on tumor malignancy
G Bossi, F Marampon, R Maor-Aloni, B Zani, V Rotter, M Oren, S Strano, ...
Cell Cycle 7 (12), 1870-1879, 2008
Degradation of mutant p53H175 protein by Zn (II) through autophagy
A Garufi, D Pucci, V D’Orazi, M Cirone, G Bossi, ML Avantaggiati, ...
Cell death & disease 5 (5), e1271-e1271, 2014
Slug (SNAI2) down-regulation by RNA interference facilitates apoptosis and inhibits invasive growth in neuroblastoma preclinical models
R Vitali, C Mancini, V Cesi, B Tanno, M Mancuso, G Bossi, Y Zhang, ...
Clinical Cancer Research 14 (14), 4622-4630, 2008
Transcriptional regulation of hypoxia-inducible factor 1α by HIPK2 suggests a novel mechanism to restrain tumor growth
L Nardinocchi, R Puca, D Guidolin, AS Belloni, G Bossi, C Michiels, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1793 (2), 368-377, 2009
Che‐1‐induced inhibition of mTOR pathway enables stress‐induced autophagy
A Desantis, T Bruno, V Catena, F De Nicola, F Goeman, S Iezzi, C Sorino, ...
The EMBO Journal 34 (9), 1214-1230, 2015
Restoring wtp53 activity in HIPK2 depleted MCF7 cells by modulating metallothionein and zinc
R Puca, L Nardinocchi, G Bossi, A Sacchi, G Rechavi, D Givol, G D'Orazi
Experimental cell research 315 (1), 67-75, 2009
In vivo and in vitro evidence that PPARγ ligands are antagonists of leptin signaling in breast cancer
S Catalano, L Mauro, D Bonofiglio, M Pellegrino, H Qi, P Rizza, D Vizza, ...
The American journal of pathology 179 (2), 1030-1040, 2011
Abscopal effect of radiation therapy: interplay between radiation dose and p53 status
L Strigari, M Mancuso, V Ubertini, A Soriani, P Giardullo, M Benassi, ...
International journal of radiation biology 90 (3), 248-255, 2014
Mutant p53 gains new function in promoting inflammatory signals by repression of the secreted interleukin-1 receptor antagonist
V Ubertini, G Norelli, D d'Arcangelo, A Gurtner, E Cesareo, S Baldari, ...
Oncogene 34 (19), 2493-2504, 2015
Expression of Slug Is Regulated by c-Myb and Is Required for Invasion and Bone Marrow Homing of Cancer Cells of Different Origin [S]
B Tanno, F Sesti, V Cesi, G Bossi, G Ferrari-Amorotti, R Bussolari, ...
Journal of Biological Chemistry 285 (38), 29434-29445, 2010
Che-1 promotes tumor cell survival by sustaining mutant p53 transcription and inhibiting DNA damage response activation
T Bruno, A Desantis, G Bossi, S Di Agostino, C Sorino, F De Nicola, ...
Cancer cell 18 (2), 122-134, 2010
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