| Multidrug efflux pumps: structure, function and regulation D Du, X Wang-Kan, A Neuberger, HW Van Veen, KM Pos, LJV Piddock, ... Nature Reviews Microbiology 16 (9), 523-539, 2018 | 837 | 2018 |
| Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism MA Seeger, A Schiefner, T Eicher, F Verrey, K Diederichs, KM Pos Science 313 (5791), 1295-1298, 2006 | 684 | 2006 |
| Drug transport mechanism of the AcrB efflux pump KM Pos Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1794 (5), 782-793, 2009 | 372 | 2009 |
| Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop T Eicher, H Cha, MA Seeger, L Brandstätter, J El-Delik, JA Bohnert, ... Proceedings of the National Academy of Sciences 109 (15), 5687-5692, 2012 | 348 | 2012 |
| Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations SMR Camargo, D Singer, V Makrides, K Huggel, KM Pos, CA Wagner, ... Gastroenterology 136 (3), 872-882. e3, 2009 | 311 | 2009 |
| Mechanisms of envelope permeability and antibiotic influx and efflux in Gram-negative bacteria M Masi, M Réfregiers, KM Pos Nature microbiology 2 (3), 1-7, 2017 | 293 | 2017 |
| Tripartite assembly of RND multidrug efflux pumps L Daury, F Orange, JC Taveau, A Verchere, L Monlezun, C Gounou, ... Nature communications 7 (1), 10731, 2016 | 234 | 2016 |
| Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives H Sjuts, AV Vargiu, SM Kwasny, ST Nguyen, HS Kim, X Ding, AR Ornik, ... Proceedings of the National Academy of Sciences 113 (13), 3509-3514, 2016 | 213 | 2016 |
| Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB T Eicher, MA Seeger, C Anselmi, W Zhou, L Brandstätter, F Verrey, ... elife 3, e03145, 2014 | 193 | 2014 |
| Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB MA Seeger, C Von Ballmoos, T Eicher, L Brandstätter, F Verrey, ... Nature structural & molecular biology 15 (2), 199-205, 2008 | 185 | 2008 |
| Approved drugs containing thiols as inhibitors of metallo-β-lactamases: strategy to combat multidrug-resistant bacteria FM Klingler, TA Wichelhaus, D Frank, J Cuesta-Bernal, J El-Delik, ... Journal of medicinal chemistry 58 (8), 3626-3630, 2015 | 184 | 2015 |
| Structure, mechanism and cooperation of bacterial multidrug transporters D Du, HW van Veen, S Murakami, KM Pos, BF Luisi Current opinion in structural biology 33, 76-91, 2015 | 178 | 2015 |
| The Escherichia coli Citrate Carrier CitT: a Member of a Novel Eubacterial Transporter Family Related to the 2-Oxoglutarate/Malate Translocator from Spinach … KM Pos, P Dimroth, M Bott Journal of Bacteriology 180 (16), 4160-4165, 1998 | 168 | 1998 |
| The AcrB efflux pump: conformational cycling and peristalsis lead to multidrug resistance MA Seeger, K Diederichs, T Eicher, L Brandstatter, A Schiefner, F Verrey, ... Current drug targets 9 (9), 729-749, 2008 | 160 | 2008 |
| Structure, assembly, and function of tripartite efflux and type 1 secretion systems in gram-negative bacteria I Alav, J Kobylka, MS Kuth, KM Pos, M Picard, JMA Blair, VN Bavro Chemical Reviews 121 (9), 5479-5596, 2021 | 152 | 2021 |
| Site-Directed Mutagenesis Reveals Putative Substrate Binding Residues in the Escherichia coli RND Efflux Pump AcrB JA Bohnert, S Schuster, MA Seeger, E Fähnrich, KM Pos, WV Kern Journal of bacteriology 190 (24), 8225-8229, 2008 | 151 | 2008 |
| A natural prodrug activation mechanism in nonribosomal peptide synthesis D Reimer, KM Pos, M Thines, P Grün, HB Bode Nature chemical biology 7 (12), 888-890, 2011 | 140 | 2011 |
| AcrB: a mean, keen, drug efflux machine J Kobylka, MS Kuth, RT Müller, ER Geertsma, KM Pos Annals of the New York Academy of Sciences 1459 (1), 38-68, 2020 | 129 | 2020 |
| Basolateral aromatic amino acid transporter TAT1 (Slc16a10) functions as an efflux pathway T Ramadan, SMR Camargo, V Summa, P Hunziker, S Chesnov, KM Pos, ... Journal of cellular physiology 206 (3), 771-779, 2006 | 118 | 2006 |
| Crucial role of Asp408 in the proton translocation pathway of multidrug transporter AcrB: evidence from site-directed mutagenesis and carbodiimide labeling MA Seeger, C von Ballmoos, F Verrey, KM Pos Biochemistry 48 (25), 5801-5812, 2009 | 104 | 2009 |
