Fekade Bruck Sime
Fekade Bruck Sime
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An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units
G Wong, A Brinkman, RJ Benefield, M Carlier, JJ De Waele, N El Helali, ...
Journal of antimicrobial chemotherapy 69 (5), 1416-1423, 2014
Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review
FB Sime, MS Roberts, SL Peake, J Lipman, JA Roberts
Annals of intensive care 2 (1), 1-11, 2012
Augmented renal clearance in critically ill patients: etiology, definition and implications for beta-lactam dose optimization
FB Sime, AA Udy, JA Roberts
Current opinion in pharmacology 24, 1-6, 2015
How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?
G Wong, FB Sime, J Lipman, JA Roberts
BMC infectious diseases 14 (1), 1-11, 2014
Optimization of dosing regimens and dosing in special populations
FB Sime, MS Roberts, JA Roberts
Clinical Microbiology and Infection 21 (10), 886-893, 2015
Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies
FB Sime, MS Roberts, JA Roberts, TA Robertson
Journal of Chromatography B 960, 134-144, 2014
Solid nanoparticles for oral antimicrobial drug delivery: A review
A Raza, FB Sime, PJ Cabot, F Maqbool, JA Roberts, JR Falconer
Drug Discovery Today 24 (3), 858-866, 2019
Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial
FB Sime, MS Roberts, IS Tiong, JH Gardner, S Lehman, SL Peake, ...
Journal of Antimicrobial Chemotherapy 70 (8), 2369-2375, 2015
What antibiotic exposures are required to suppress the emergence of resistance for Gram-negative bacteria? A systematic review
CD Sumi, AJ Heffernan, J Lipman, JA Roberts, FB Sime
Clinical Pharmacokinetics 58 (11), 1407-1443, 2019
Individualising therapy to minimize bacterial multidrug resistance
AJ Heffernan, FB Sime, J Lipman, JA Roberts
Drugs 78 (6), 621-641, 2018
Optimizing dosing of antibiotics in critically ill patients
SL Parker, FB Sime, JA Roberts
Current Opinion in Infectious Diseases 28 (6), 497-504, 2015
Altered pharmacokinetics of piperacillin in febrile neutropenic patients with hematological malignancy
FB Sime, MS Roberts, MS Warner, U Hahn, TA Robertson, S Yeend, ...
Antimicrobial agents and chemotherapy 58 (6), 3533-3537, 2014
The global prevalence of multidrug-resistance among Acinetobacter baumannii causing hospital-acquired and ventilator-associated pneumonia and its associated mortality: A …
SMS Lim, AZ Abidin, SM Liew, JA Roberts, FB Sime
Journal of Infection 79 (6), 593-600, 2019
Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by Gram-negative bacilli: a systematic review
AJ Heffernan, FB Sime, J Lipman, J Dhanani, K Andrews, D Ellwood, ...
International journal of antimicrobial agents 53 (3), 234-245, 2019
Population pharmacokinetics of unbound ceftolozane and tazobactam in critically ill patients without renal dysfunction
FB Sime, M Lassig-Smith, T Starr, J Stuart, S Pandey, SL Parker, ...
Antimicrobial Agents and Chemotherapy 63 (10), e01265-19, 2019
Pharmacodynamics of aerosolized fosfomycin and amikacin against resistant clinical isolates of Pseudomonas aeruginosa and Klebsiella pneumoniae in a hollow-fiber infection …
FB Sime, A Johnson, S Whalley, A Santoyo-Castelazo, AB Montgomery, ...
Antimicrobial agents and chemotherapy 61 (1), e01763-16, 2017
How to optimize antibiotic pharmacokinetic/pharmacodynamics for Gram-negative infections in critically ill patients
AJ Heffernan, FB Sime, FS Taccone, JA Roberts
Current Opinion in Infectious Diseases 31 (6), 555-565, 2018
A population pharmacokinetic model-guided evaluation of ceftolozane-tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration
FB Sime, M Lassig-Smith, T Starr, J Stuart, S Pandey, SL Parker, ...
Antimicrobial agents and chemotherapy 64 (1), e01655-19, 2019
Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignancies
FB Sime, MS Roberts, IS Tiong, JH Gardner, S Lehman, SL Peake, ...
Antimicrobial Agents and Chemotherapy 59 (9), 5463-5469, 2015
Population pharmacokinetics of total and unbound concentrations of intravenous posaconazole in adult critically ill patients
FB Sime, CJ Byrne, S Parker, J Stuart, J Butler, T Starr, S Pandey, ...
Critical Care 23 (1), 1-12, 2019
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