David Gorkin
David Gorkin
Email verificata su emory.edu - Home page
Citata da
Citata da
CRISPR inversion of CTCF sites alters genome topology and enhancer/promoter function
Y Guo, Q Xu, D Canzio, J Shou, J Li, DU Gorkin, I Jung, H Wu, Y Zhai, ...
Cell 162 (4), 900-910, 2015
Chromatin domains: the unit of chromosome organization
JR Dixon, DU Gorkin, B Ren
Molecular cell 62 (5), 668-680, 2016
Multi-platform discovery of haplotype-resolved structural variation in human genomes
MJP Chaisson, AD Sanders, X Zhao, A Malhotra, D Porubsky, T Rausch, ...
Nature communications 10 (1), 1-16, 2019
A method to predict the impact of regulatory variants from DNA sequence
D Lee, DU Gorkin, M Baker, BJ Strober, AL Asoni, AS McCallion, MA Beer
Nature genetics 47 (8), 955-961, 2015
The 3D genome in transcriptional regulation and pluripotency
DU Gorkin, D Leung, B Ren
Cell stem cell 14 (6), 762-775, 2014
Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation
S Preissl, R Fang, H Huang, Y Zhao, R Raviram, DU Gorkin, Y Zhang, ...
Nature neuroscience 21 (3), 432-439, 2018
Expanded encyclopaedias of DNA elements in the human and mouse genomes
JE Moore, MJ Purcaro, HE Pratt, CB Epstein, N Shoresh, J Adrian, T Kawli, ...
Nature 583 (7818), 699-710, 2020
A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway
C Praetorius, C Grill, SN Stacey, AM Metcalf, DU Gorkin, KC Robinson, ...
Cell 155 (5), 1022-1033, 2013
N6-methyladenine DNA modification in glioblastoma
Q Xie, TP Wu, RC Gimple, Z Li, BC Prager, Q Wu, Y Yu, P Wang, Y Wang, ...
Cell 175 (5), 1228-1243. e20, 2018
Genome-wide compendium and functional assessment of in vivo heart enhancers
DE Dickel, I Barozzi, Y Zhu, Y Fukuda-Yuzawa, M Osterwalder, ...
Nature communications 7 (1), 1-13, 2016
An atlas of dynamic chromatin landscapes in mouse fetal development
DU Gorkin, I Barozzi, Y Zhao, Y Zhang, H Huang, AY Lee, B Li, J Chiou, ...
Nature 583 (7818), 744-751, 2020
Improved regulatory element prediction based on tissue-specific local epigenomic signatures
Y He, DU Gorkin, DE Dickel, JR Nery, RG Castanon, AY Lee, Y Shen, ...
Proceedings of the National Academy of Sciences 114 (9), E1633-E1640, 2017
Integration of ChIP-seq and machine learning reveals enhancers and a predictive regulatory sequence vocabulary in melanocytes
DU Gorkin, D Lee, X Reed, C Fletez-Brant, SL Bessling, SK Loftus, ...
Genome research 22 (11), 2290-2301, 2012
Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations
J Lauring, DP Cosgrove, S Fontana, JP Gustin, H Konishi, AM Abukhdeir, ...
Oncogene 29 (16), 2337-2345, 2010
SOX10 directly modulates ERBB3 transcription via an intronic neural crest enhancer
MK Prasad, X Reed, DU Gorkin, JC Cronin, AR McAdow, K Chain, ...
BMC developmental biology 11 (1), 1-14, 2011
CTCF Promotes Long-range Enhancer-promoter Interactions and Lineage-specific Gene Expression in Mammalian Cells
N Kubo, H Ishii, X Xiong, S Bianco, F Meitinger, R Hu, JD Hocker, ...
BioRxiv, 2020
Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk
WW Greenwald, J Chiou, J Yan, Y Qiu, N Dai, A Wang, N Nariai, ...
Nature communications 10 (1), 1-12, 2019
Common DNA sequence variation influences 3-dimensional conformation of the human genome
DU Gorkin, Y Qiu, M Hu, K Fletez-Brant, T Liu, AD Schmitt, A Noor, ...
Genome biology 20 (1), 1-25, 2019
Spatiotemporal DNA methylome dynamics of the developing mouse fetus
Y He, M Hariharan, DU Gorkin, DE Dickel, C Luo, RG Castanon, JR Nery, ...
Nature 583 (7818), 752-759, 2020
Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes
TD Fufa, ML Harris, DE Watkins-Chow, D Levy, DU Gorkin, DE Gildea, ...
Human molecular genetics 24 (19), 5433-5450, 2015
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