| Targeting glioma stem cells through combined BMI1 and EZH2 inhibition X Jin, LJY Kim, Q Wu, LC Wallace, BC Prager, T Sanvoranart, RC Gimple, ... Nature medicine 23 (11), 1352-1361, 2017 | 334 | 2017 |
| N6-methyladenine DNA modification in glioblastoma Q Xie, TP Wu, RC Gimple, Z Li, BC Prager, Q Wu, Y Yu, P Wang, Y Wang, ... Cell 175 (5), 1228-1243. e20, 2018 | 254 | 2018 |
| The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells D Dixit, BC Prager, RC Gimple, HX Poh, Y Wang, Q Wu, Z Qiu, RL Kidwell, ... Cancer discovery 11 (2), 480-499, 2021 | 243 | 2021 |
| Reciprocal signaling between glioblastoma stem cells and differentiated tumor cells promotes malignant progression X Wang, BC Prager, Q Wu, LJY Kim, RC Gimple, Y Shi, K Yang, ... Cell stem cell 22 (4), 514-528. e5, 2018 | 219 | 2018 |
| Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling SC Mack, KW Pajtler, L Chavez, K Okonechnikov, KC Bertrand, X Wang, ... Nature 553 (7686), 101-105, 2018 | 195 | 2018 |
| Transcription elongation factors represent in vivo cancer dependencies in glioblastoma TE Miller, BB Liau, LC Wallace, AR Morton, Q Xie, D Dixit, DC Factor, ... Nature 547 (7663), 355-359, 2017 | 193 | 2017 |
| Targeting glioblastoma stem cells through disruption of the circadian clock Z Dong, G Zhang, M Qu, RC Gimple, Q Wu, Z Qiu, BC Prager, X Wang, ... Cancer discovery 9 (11), 1556-1573, 2019 | 186 | 2019 |
| Purine synthesis promotes maintenance of brain tumor initiating cells in glioma X Wang, K Yang, Q Xie, Q Wu, SC Mack, Y Shi, LJY Kim, BC Prager, ... Nature neuroscience 20 (5), 661-673, 2017 | 172 | 2017 |
| Abnormal B cell memory subsets dominate HIV-specific responses in infected individuals L Kardava, S Moir, N Shah, W Wang, R Wilson, CM Buckner, BH Santich, ... The Journal of clinical investigation 124 (7), 3252-3262, 2014 | 145 | 2014 |
| Glioma stem cell–specific superenhancer promotes polyunsaturated fatty-acid synthesis to support EGFR signaling RC Gimple, RL Kidwell, LJY Kim, T Sun, AD Gromovsky, Q Wu, M Wolf, ... Cancer discovery 9 (9), 1248-1267, 2019 | 140 | 2019 |
| Glycosylation, hypogammaglobulinemia, and resistance to viral infections MA Sadat, S Moir, TW Chun, P Lusso, G Kaplan, L Wolfe, MJ Memoli, ... New England Journal of Medicine 370 (17), 1615-1625, 2014 | 140 | 2014 |
| Zika virus targets glioblastoma stem cells through a SOX2-integrin αvβ5 axis Z Zhu, P Mesci, JA Bernatchez, RC Gimple, X Wang, ST Schafer, ... Cell stem cell 26 (2), 187-204. e10, 2020 | 139 | 2020 |
| Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells X Wang, K Yang, Q Wu, LJY Kim, AR Morton, RC Gimple, BC Prager, ... Science translational medicine 11 (504), eaau4972, 2019 | 125 | 2019 |
| Ibrutinib inactivates BMX-STAT3 in glioma stem cells to impair malignant growth and radioresistance Y Shi, OA Guryanova, W Zhou, C Liu, Z Huang, X Fang, X Wang, C Chen, ... Science translational medicine 10 (443), eaah6816, 2018 | 124 | 2018 |
| MYC-regulated mevalonate metabolism maintains brain tumor–initiating cells X Wang, Z Huang, Q Wu, BC Prager, SC Mack, K Yang, LJY Kim, ... Cancer research 77 (18), 4947-4960, 2017 | 108 | 2017 |
| Nicotinamide metabolism regulates glioblastoma stem cell maintenance J Jung, LJY Kim, X Wang, Q Wu, T Sanvoranart, CG Hubert, BC Prager, ... JCI insight 2 (10), 2017 | 100 | 2017 |
| Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma SC Mack, I Singh, X Wang, R Hirsch, Q Wu, R Villagomez, JA Bernatchez, ... Journal of Experimental Medicine 216 (5), 1071-1090, 2019 | 99 | 2019 |
| Metabolic regulation of the epigenome drives lethal infantile ependymoma KA Michealraj, SA Kumar, LJY Kim, FMG Cavalli, D Przelicki, JB Wojcik, ... Cell 181 (6), 1329-1345. e24, 2020 | 90 | 2020 |
| CRISPR screening of CAR T cells and cancer stem cells reveals critical dependencies for cell-based therapies D Wang, BC Prager, RC Gimple, B Aguilar, D Alizadeh, H Tang, D Lv, ... Cancer discovery 11 (5), 1192-1211, 2021 | 89 | 2021 |
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Jeremy N. RichUniversity of PittsburghVerified email at upmc.edu
