| A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties JM Murphy, Q Zhang, SN Young, ML Reese, FP Bailey, PA Eyers, ... Biochemical Journal 457 (2), 323-334, 2014 | 271 | 2014 |
| Anomalous and normal diffusion of proteins and lipids in crowded lipid membranes M Javanainen, H Hammaren, L Monticelli, JH Jeon, MS Miettinen, ... Faraday discussions 161, 397-417, 2013 | 218 | 2013 |
| The regulation of JAKs in cytokine signaling and its breakdown in disease HM Hammarén, AT Virtanen, J Raivola, O Silvennoinen Cytokine 118, 48-63, 2019 | 195 | 2019 |
| Membrane proteins diffuse as dynamic complexes with lipids PS Niemela, MS Miettinen, L Monticelli, H Hammaren, P Bjelkmar, ... Journal of the American Chemical Society 132 (22), 7574-7575, 2010 | 195 | 2010 |
| Molecular basis for pseudokinase-dependent autoinhibition of JAK2 tyrosine kinase Y Shan, K Gnanasambandan, D Ungureanu, ET Kim, H Hammarén, ... Nature structural & molecular biology 21 (7), 579-584, 2014 | 154 | 2014 |
| ATP binding to the pseudokinase domain of JAK2 is critical for pathogenic activation HM Hammarén, D Ungureanu, J Grisouard, RC Skoda, SR Hubbard, ... Proceedings of the National Academy of Sciences 112 (15), 4642-4647, 2015 | 107 | 2015 |
| Enhancement of adhesion and promotion of osteogenic differentiation of human adipose stem cells by poled electroactive poly (vinylidene fluoride) J Pärssinen, H Hammarén, R Rahikainen, V Sencadas, C Ribeiro, ... Journal of Biomedical Materials Research Part A 103 (3), 919-928, 2015 | 98 | 2015 |
| Control of protein stability by post-translational modifications JM Lee, HM Hammarén, MM Savitski, SH Baek Nature Communications 14 (1), 201, 2023 | 95 | 2023 |
| Structural and functional characterization of the JH2 pseudokinase domain of JAK family tyrosine kinase 2 (TYK2) X Min, D Ungureanu, S Maxwell, H Hammarén, S Thibault, EK Hillert, ... Journal of Biological Chemistry 290 (45), 27261-27270, 2015 | 90 | 2015 |
| New insights into the structure and function of the pseudokinase domain in JAK2 O Silvennoinen, D Ungureanu, Y Niranjan, H Hammaren, ... Biochemical Society Transactions 41 (4), 1002-1007, 2013 | 53 | 2013 |
| Nucleotide-binding mechanisms in pseudokinases HM Hammarén, AT Virtanen, O Silvennoinen Bioscience reports 36 (1), e00282, 2016 | 46 | 2016 |
| Identification and characterization of JAK2 pseudokinase domain small molecule binders DE Puleo, K Kucera, HM Hammarén, D Ungureanu, AS Newton, ... ACS medicinal chemistry letters 8 (6), 618-621, 2017 | 44 | 2017 |
| Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses LN Varghese, D Ungureanu, NPD Liau, SN Young, A Laktyushin, ... Biochemical Journal 458 (2), 395-405, 2014 | 40 | 2014 |
| Connection between Absorption Properties and Conformational Changes in Deinococcus radiodurans Phytochrome H Takala, H Lehtivuori, H Hammarén, VP Hytonen, JA Ihalainen Biochemistry 53 (45), 7076-7085, 2014 | 35 | 2014 |
| Janus kinase 2 activation mechanisms revealed by analysis of suppressing mutations HM Hammarén, AT Virtanen, BG Abraham, H Peussa, SR Hubbard, ... Journal of Allergy and Clinical Immunology 143 (4), 1549-1559. e6, 2019 | 28 | 2019 |
| The JH2 domain and SH2-JH2 linker regulate JAK2 activity: A detailed kinetic analysis of wild type and V617F mutant kinase domains AS Sanz, Y Niranjan, H Hammarén, D Ungureanu, R Ruijtenbeek, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844 (10), 1835-1841, 2014 | 24 | 2014 |
| Bifunctional avidin with covalently modifiable ligand binding site J Leppiniemi, JAE Määttä, H Hammaren, M Soikkeli, M Laitaoja, J Jänis, ... PLoS One 6 (1), e16576, 2011 | 24 | 2011 |
| Glycolytic flux-signaling controls mouse embryo mesoderm development H Miyazawa, MT Snaebjornsson, N Prior, E Kafkia, HM Hammarén, ... Elife 11, e83299, 2022 | 19 | 2022 |
| Hyperactivation of oncogenic JAK3 mutants depend on ATP binding to the pseudokinase domain J Raivola, HM Hammarén, AT Virtanen, V Bulleeraz, AC Ward, ... Frontiers in oncology 8, 560, 2018 | 15 | 2018 |
| Thermal proteome profiling: Insights into protein modifications, associations, and functions C Le Sueur, HM Hammarén, S Sridharan, MM Savitski Current opinion in chemical biology 71, 102225, 2022 | 14 | 2022 |
Stevan R. HubbardNYU School of MedicineVerified email at med.nyu.edu
