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Sidong Huang
Sidong Huang
Verified email at mcgill.ca
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Year
Unresponsiveness of colon cancer to BRAF (V600E) inhibition through feedback activation of EGFR
A Prahallad, C Sun, S Huang, F Di Nicolantonio, R Salazar, D Zecchin, ...
Nature 483 (7387), 100-103, 2012
21512012
Reversible and adaptive resistance to BRAF (V600E) inhibition in melanoma
C Sun, L Wang, S Huang, GJJE Heynen, A Prahallad, C Robert, ...
Nature 508 (7494), 118-122, 2014
8752014
MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling
S Huang, M Hölzel, T Knijnenburg, A Schlicker, P Roepman, U McDermott, ...
Cell 151 (5), 937-950, 2012
4752012
Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3
C Sun, S Hobor, A Bertotti, D Zecchin, S Huang, F Galimi, F Cottino, ...
Cell reports 7 (1), 86-93, 2014
3432014
NF1 is a tumor suppressor in neuroblastoma that determines retinoic acid response and disease outcome
M Hölzel, S Huang, J Koster, I Øra, A Lakeman, H Caron, W Nijkamp, ...
Cell 142 (2), 218-229, 2010
2252010
Identification of a candidate modifying gene for spinal muscular atrophy by comparative genomics
JM Scharf, MG Endrizzi, A Wetter, S Huang, TG Thompson, K Zerres, ...
Nature genetics 20 (1), 83-86, 1998
1691998
ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome
S Huang, J Laoukili, MT Epping, J Koster, M Hölzel, BA Westerman, ...
Cancer cell 15 (4), 328-340, 2009
1542009
SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer
Y Xue, B Meehan, Z Fu, XQD Wang, PO Fiset, R Rieker, C Levins, T Kong, ...
Nature communications 10 (1), 557, 2019
1512019
Phosphorylation of the translation initiation factor eIF2α at serine 51 determines the cell fate decisions of Akt in response to oxidative stress
K Rajesh, J Krishnamoorthy, U Kazimierczak, C Tenkerian, AI Papadakis, ...
Cell death & disease 6 (1), e1591-e1591, 2015
1302015
Expression of DRD2 is increased in human pancreatic ductal adenocarcinoma and inhibitors slow tumor growth in mice
P Jandaghi, HS Najafabadi, AS Bauer, AI Papadakis, M Fassan, A Hall, ...
Gastroenterology 151 (6), 1218-1231, 2016
1242016
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary
Y Xue, B Meehan, E Macdonald, S Venneti, XQD Wang, L Witkowski, ...
Nature communications 10 (1), 558, 2019
1102019
CD44 promotes PD-L1 expression and its tumor-intrinsic function in breast and lung cancers
T Kong, R Ahn, K Yang, X Zhu, Z Fu, G Morin, R Bramley, NC Cliffe, Y Xue, ...
Cancer research 80 (3), 444-457, 2020
1072020
Small-cell carcinoma of the ovary, hypercalcemic type–genetics, new treatment targets, and current management guidelines
M Tischkowitz, S Huang, S Banerjee, J Hague, WPD Hendricks, ...
Clinical Cancer Research 26 (15), 3908-3917, 2020
952020
Loss of p53 induces cell proliferation via Ras-independent activation of the Raf/Mek/Erk signaling pathway
M Drosten, EYM Sum, CG Lechuga, L Simón-Carrasco, HKC Jacob, ...
Proceedings of the National Academy of Sciences 111 (42), 15155-15160, 2014
942014
A Systematic High-Throughput Screen of a Yeast Deletion Collection for Mutants Defective in PHO5 Regulation
S Huang, EK O'Shea
Genetics 169 (4), 1859-1871, 2005
742005
MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma
Y Zhan, J Guo, W Yang, C Goncalves, T Rzymski, A Dreas, E Żyłkiewicz, ...
The Journal of clinical investigation 127 (11), 4179-4192, 2017
682017
SMARCE1 suppresses EGFR expression and controls responses to MET and ALK inhibitors in lung cancer
AI Papadakis, C Sun, TA Knijnenburg, Y Xue, W Grernrum, M Hölzel, ...
Cell research 25 (4), 445-458, 2015
672015
SWI/SNF-compromised cancers are susceptible to bromodomain inhibitors
T Shorstova, M Marques, J Su, J Johnston, CL Kleinman, N Hamel, ...
Cancer research 79 (10), 2761-2774, 2019
642019
A general framework for interrogation of mRNA stability programs identifies RNA-binding proteins that govern cancer transcriptomes
G Perron, P Jandaghi, S Solanki, M Safisamghabadi, C Storoz, ...
Cell Reports 23 (6), 1639-1650, 2018
622018
Functional analysis of the cyclin-dependent kinase inhibitor Pho81 identifies a novel inhibitory domain
S Huang, DA Jeffery, MD Anthony, EK O'Shea
Molecular and Cellular Biology 21 (19), 6695-6705, 2001
542001
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