SARS-CoV-2 spike protein co-opts VEGF-A/neuropilin-1 receptor signaling to induce analgesia A Moutal, LF Martin, L Boinon, K Gomez, D Ran, Y Zhou, HJ Stratton, ... Pain 162 (1), 243-252, 2021 | 152 | 2021 |
CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide A Moutal, X Yang, W Li, KB Gilbraith, S Luo, S Cai, L François-Moutal, ... Pain 158 (12), 2301-2319, 2017 | 75 | 2017 |
Dissecting the role of the CRMP2–neurofibromin complex on pain behaviors A Moutal, Y Wang, X Yang, Y Ji, S Luo, A Dorame, SS Bellampalli, ... Pain 158 (11), 2203-2221, 2017 | 57 | 2017 |
Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury–associated peripheral sensory neuropathy via block of N-and T … SS Bellampalli, Y Ji, A Moutal, S Cai, EMK Wijeratne, MA Gandini, J Yu, ... Pain 160 (1), 117-135, 2019 | 53 | 2019 |
HiPSC-derived retinal ganglion cells grow dendritic arbors and functional axons on a tissue-engineered scaffold K Li, X Zhong, S Yang, Z Luo, K Li, Y Liu, S Cai, H Gu, S Lu, H Zhang, ... Acta biomaterialia 54, 117-127, 2017 | 53 | 2017 |
Targeting T-type/CaV3. 2 channels for chronic pain S Cai, K Gomez, A Moutal, R Khanna Translational Research 234, 20-30, 2021 | 48 | 2021 |
A porcine model of neurofibromatosis type 1 that mimics the human disease KA White, VJ Swier, JT Cain, JL Kohlmeyer, DK Meyerholz, MR Tanas, ... JCI insight 3 (12), 2018 | 45 | 2018 |
A Modular Assembly of Spinal Cord–Like Tissue Allows Targeted Tissue Repair in the Transected Spinal Cord BQ Lai, B Feng, MT Che, LJ Wang, S Cai, MY Huang, HY Gu, B Jiang, ... Advanced science 5 (9), 1800261, 2018 | 43 | 2018 |
Di (2-ethylhexyl) phthalate modulates cholinergic mini-presynaptic transmission of projection neurons in Drosophila antennal lobe D Ran, S Cai, H Wu, H Gu Food and chemical toxicology 50 (9), 3291-3297, 2012 | 42 | 2012 |
Homology‐guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2‐derived peptides A Moutal, W Li, Y Wang, W Ju, S Luo, S Cai, L François‐Moutal, ... British journal of pharmacology 175 (12), 2244-2260, 2018 | 41 | 2018 |
CRMP2–Neurofibromin interface drives NF1-related pain A Moutal, L Sun, X Yang, W Li, S Cai, S Luo, R Khanna Neuroscience 381, 79-90, 2018 | 37 | 2018 |
Studies on CRMP2 SUMOylation–deficient transgenic mice identify sex-specific Nav1. 7 regulation in the pathogenesis of chronic neuropathic pain A Moutal, S Cai, J Yu, HJ Stratton, A Chefdeville, K Gomez, D Ran, ... Pain 161 (11), 2629-2651, 2020 | 31 | 2020 |
Reversal of peripheral neuropathic pain by the small-molecule natural product Physalin F via block of CaV2. 3 (R-type) and CaV2. 2 (N-type) voltage-gated calcium channels Z Shan, S Cai, J Yu, Z Zhang, TGM Vallecillo, MJ Serafini, AM Thomas, ... ACS chemical neuroscience 10 (6), 2939-2955, 2019 | 30 | 2019 |
CRMP2 is necessary for Neurofibromatosis type 1 related pain A Moutal, S Cai, S Luo, R Voisin, R Khanna Channels 12 (1), 47-50, 2018 | 30 | 2018 |
(−)-Hardwickiic acid and Hautriwaic acid induce Antinociception via blockade of Tetrodotoxin-sensitive voltage-dependent sodium channels S Cai, SS Bellampalli, J Yu, W Li, Y Ji, EMK Wijeratne, A Dorame, S Luo, ... ACS Chemical Neuroscience 10 (3), 1716-1728, 2018 | 25 | 2018 |
The natural flavonoid naringenin elicits analgesia through inhibition of NaV1. 8 voltage-gated sodium channels Y Zhou, S Cai, A Moutal, J Yu, K Gómez, CL Madura, Z Shan, NYN Pham, ... ACS Chemical Neuroscience 10 (12), 4834-4846, 2019 | 23 | 2019 |
Selective targeting of NaV1. 7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents S Cai, A Moutal, J Yu, LA Chew, J Isensee, R Chawla, K Gomez, S Luo, ... Science Translational Medicine 13 (619), eabh1314, 2021 | 22 | 2021 |
Development and characterization of an injury-free model of functional pain in rats by exposure to red light R Khanna, A Patwardhan, X Yang, W Li, S Cai, Y Ji, LA Chew, A Dorame, ... The journal of pain 20 (11), 1293-1306, 2019 | 20 | 2019 |
High fidelity cryopreservation and recovery of primary rodent cortical neurons SS Parker, A Moutal, S Cai, S Chandrasekaran, MR Roman, AA Koshy, ... ENeuro 5 (5), 2018 | 20 | 2018 |
Tetramethylpyrazine reduces epileptogenesis progression in electrical kindling models by modulating hippocampal excitatory neurotransmission Y Jin, S Cai, Y Jiang, K Zhong, C Wen, Y Ruan, LA Chew, R Khanna, Z Xu, ... ACS Chemical Neuroscience 10 (12), 4854-4863, 2019 | 15 | 2019 |