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Robert Szulcek
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Electric cell-substrate impedance sensing for the quantification of endothelial proliferation, barrier function, and motility
R Szulcek, HJ Bogaard, GP van Nieuw Amerongen
JoVE (Journal of Visualized Experiments), e51300, 2014
2782014
Multicenter preclinical validation of BET inhibition for the treatment of pulmonary arterial hypertension
DE Van der Feen, K Kurakula, E Tremblay, O Boucherat, GPL Bossers, ...
American journal of respiratory and critical care medicine 200 (7), 910-920, 2019
1102019
Delayed microvascular shear adaptation in pulmonary arterial hypertension. Role of platelet endothelial cell adhesion molecule-1 cleavage
R Szulcek, CM Happe, N Rol, RD Fontijn, C Dickhoff, KJ Hartemink, ...
American journal of respiratory and critical care medicine 193 (12), 1410-1420, 2016
1042016
Contribution of impaired parasympathetic activity to right ventricular dysfunction and pulmonary vascular remodeling in pulmonary arterial hypertension
D da Silva Gonçalves Bós, CEE Van Der Bruggen, K Kurakula, XQ Sun, ...
Circulation 137 (9), 910-924, 2018
1002018
Localized RhoA GTPase activity regulates dynamics of endothelial monolayer integrity
R Szulcek, CML Beckers, J Hodzic, J de Wit, Z Chen, T Grob, RJP Musters, ...
Cardiovascular research 99 (3), 471-482, 2013
872013
Cellular senescence impairs the reversibility of pulmonary arterial hypertension
DE Van Der Feen, GPL Bossers, QAJ Hagdorn, JR Moonen, K Kurakula, ...
Science Translational Medicine 12 (554), eaaw4974, 2020
802020
Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension
HA Sindi, G Russomanno, S Satta, VB Abdul-Salam, KB Jo, ...
Nature communications 11 (1), 1185, 2020
712020
Nitrosation-dependent caveolin 1 phosphorylation, ubiquitination, and degradation and its association with idiopathic pulmonary arterial hypertension
FR Bakhshi, M Mao, AN Shajahan, T Piegeler, Z Chen, O Chernaya, ...
Pulmonary circulation 3 (4), 816-830, 2013
712013
Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension
N Rol, MA de Raaf, XQ Sun, VP Kuiper, D da Silva Gonçalves Bos, ...
Cardiovascular research 115 (2), 432-439, 2019
402019
Endothelial dysfunction in pulmonary arterial hypertension: loss of cilia length regulation upon cytokine stimulation
A Dummer, N Rol, R Szulcek, K Kurakula, X Pan, BI Visser, HJ Bogaard, ...
Pulmonary circulation 8 (2), 2045894018764629, 2018
382018
Autophagy contributes to BMP type 2 receptor degradation and development of pulmonary arterial hypertension
MC Gomez‐Puerto, I van Zuijen, CJZ Huang, R Szulcek, X Pan, ...
The Journal of pathology 249 (3), 356-367, 2019
362019
Long non-coding RNA LASSIE regulates shear stress sensing and endothelial barrier function
L Stanicek, N Lozano-Vidal, DI Bink, A Hooglugt, W Yao, I Wittig, ...
Communications biology 3 (1), 265, 2020
342020
Extracellular matrix protein ratios in the human heart and vessels: how to distinguish pathological from physiological changes?
C Wittig, R Szulcek
Frontiers in Physiology 12, 708656, 2021
332021
Stiffness-induced endothelial DLC-1 expression forces leukocyte spreading through stabilization of the ICAM-1 adhesome
L Schimmel, M van der Stoel, C Rianna, AM van Stalborch, A de Ligt, ...
Cell reports 24 (12), 3115-3124, 2018
332018
Epigenetic modification of the von Willebrand factor promoter drives platelet aggregation on the pulmonary endothelium in chronic thromboembolic pulmonary hypertension
XD Manz, R Szulcek, X Pan, P Symersky, C Dickhoff, J Majolée, V Kremer, ...
American journal of respiratory and critical care medicine 205 (7), 806-818, 2022
322022
THSD1 preserves vascular integrity and protects against intraplaque haemorrhaging in ApoE−/− mice
RA Haasdijk, WK Den Dekker, C Cheng, D Tempel, R Szulcek, FL Bos, ...
Cardiovascular research 110 (1), 129-139, 2016
322016
Microcirculatory perfusion disturbances following cardiac surgery with cardiopulmonary bypass are associated with in vitro endothelial hyperpermeability and increased …
NAM Dekker, ALI van Leeuwen, WWJ van Strien, J Majolée, R Szulcek, ...
Critical care 23, 1-10, 2019
282019
Exacerbated inflammatory signaling underlies aberrant response to BMP9 in pulmonary arterial hypertension lung endothelial cells
R Szulcek, G Sanchez-Duffhues, N Rol, X Pan, R Tsonaka, C Dickhoff, ...
Angiogenesis 23, 699-714, 2020
272020
Transient intervals of hyper-gravity enhance endothelial barrier integrity: impact of mechanical and gravitational forces measured electrically
R Szulcek, J van Bezu, J Boonstra, JJWA van Loon, ...
PLoS One 10 (12), e0144269, 2015
202015
Blood outgrowth and proliferation of endothelial colony forming cells are related to markers of disease severity in patients with pulmonary arterial hypertension
J Smits, D Tasev, S Andersen, R Szulcek, L Botros, S Ringgaard, ...
International journal of molecular sciences 19 (12), 3763, 2018
182018
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Articles 1–20