Aidan MacNamara
Aidan MacNamara
Senior Data Scientist, Bayer
Verified email at
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CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms
C Terfve, T Cokelaer, D Henriques, A MacNamara, E Goncalves, ...
BMC systems biology 6, 1-14, 2012
MEIGO: an open-source software suite based on metaheuristics for global optimization in systems biology and bioinformatics
JA Egea, D Henriques, T Cokelaer, AF Villaverde, A MacNamara, ...
BMC bioinformatics 15, 1-9, 2014
HLA class I binding of HBZ determines outcome in HTLV-1 infection
A MacNamara, A Rowan, S Hilburn, U Kadolsky, H Fujiwara, K Suemori, ...
PLoS pathogens 6 (9), e1001117, 2010
KIR2DL2 Enhances Protective and Detrimental HLA Class I-Mediated Immunity in Chronic Viral Infection
NK Seich al Basatena, A MacNamara, AM Vine, CL Thio, J Astemborski, ...
PLoS pathogens 7 (10), e1002270, 2011
State–time spectrum of signal transduction logic models
A MacNamara, C Terfve, D Henriques, BP Bernabé, J Saez-Rodriguez
Physical biology 9 (4), 045003, 2012
A rapidly reversible chemical dimerizer system to study lipid signaling in living cells
S Feng, V Laketa, F Stein, A Rutkowska, A MacNamara, S Depner, ...
Angewandte Chemie 126 (26), 6838-6841, 2014
In vivo expression of human T-lymphotropic virus type 1 basic leucine-zipper protein generates specific CD8+ and CD4+ T-lymphocyte responses that correlate with clinical outcome
S Hilburn, A Rowan, MA Demontis, A MacNamara, B Asquith, ...
Journal of Infectious Diseases 203 (4), 529-536, 2011
The avidity and lytic efficiency of the CTL response to HTLV-1
T Kattan, A MacNamara, AG Rowan, H Nose, AJ Mosley, Y Tanaka, ...
The Journal of Immunology 182 (9), 5723-5729, 2009
Modeling signaling networks to advance new cancer therapies
J Saez-Rodriguez, A MacNamara, S Cook
Annual review of biomedical engineering 17, 143-163, 2015
PIP3 induces the recycling of receptor tyrosine kinases
V Laketa, S Zarbakhsh, A Traynor-Kaplan, A MacNamara, ...
Science signaling 7 (308), ra5-ra5, 2014
T-cell epitope prediction: rescaling can mask biological variation between MHC molecules
A MacNamara, U Kadolsky, CRM Bangham, B Asquith
PLoS computational biology 5 (3), e1000327, 2009
Genetic and environmental determinants of diastolic heart function
M Thanaj, J Mielke, KA McGurk, W Bai, N Savioli, A de Marvao, HV Meyer, ...
Nature cardiovascular research 1 (4), 361-371, 2022
Network and pathway expansion of genetic disease associations identifies successful drug targets
A MacNamara, N Nakic, A Amin Al Olama, C Guo, KB Sieber, MR Hurle, ...
Scientific reports 10 (1), 20970, 2020
In contrast to HIV, KIR3DS1 does not influence outcome in HTLV-1 retroviral infection
GM O’Connor, NKS Al Basatena, V Olavarria, A MacNamara, A Vine, ...
Human immunology 73 (8), 783-787, 2012
Modeling signaling networks with different formalisms: a preview
A MacNamara, D Henriques, J Saez-Rodriguez
In Silico Systems Biology, 89-105, 2013
Experimental and computational analysis of newly identified pathogenic mutations in the creatine transporter SLC6A8
E Ferrada, T Wiedmer, WA Wang, F Frommelt, B Steurer, C Klimek, ...
Journal of Molecular Biology 436 (2), 168383, 2024
A single-cell model of PIP3 dynamics using chemical dimerization
A MacNamara, F Stein, S Feng, C Schultz, J Saez-Rodriguez
Bioorganic & Medicinal Chemistry 23 (12), 2868-2876, 2015
An IFN-γ ELISPOT assay with two CTL epitopes derived from HTLV-1 Tax region 161-233 discriminates HAM/TSP patients from asymptomatic HTLV-1 carriers in a Peruvian population.
I Best, G López, M Talledo, A Macnamara, K Verdonck, E González, ...
AIDS research and human retroviruses, 2011
Frequency and function of KIR+ CD8+ T cells in HTLV-1 infection
K Twigger, A Rowan, NK Seich al Basatena, A MacNamara, C Retiere, ...
Retrovirology 11, 1-1, 2014
Training of boolean logic models of signalling networks using prior knowledge networks and perturbation data with CellNOptR
C Terfve, T Cokelaer, A MacNamara, J Saez-Rodriguez
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