Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein B Allen, E Ingram, M Takao, MJ Smith, R Jakes, K Virdee, H Yoshida, ... Journal of Neuroscience 22 (21), 9340-9351, 2002 | 792 | 2002 |
Tau and tauopathies T Arendt, JT Stieler, M Holzer Brain research bulletin 126, 238-292, 2016 | 597 | 2016 |
Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals T Arendt, J Stieler, AM Strijkstra, RA Hut, J Rüdiger, EA Van der Zee, ... Journal of Neuroscience 23 (18), 6972-6981, 2003 | 425 | 2003 |
Glutaminyl cyclase inhibition attenuates pyroglutamate Aβ and Alzheimer's disease–like pathology S Schilling, U Zeitschel, T Hoffmann, U Heiser, M Francke, A Kehlen, ... Nature medicine 14 (10), 1106-1111, 2008 | 404 | 2008 |
A family of protein-deglutamylating enzymes associated with neurodegeneration K Rogowski, J Van Dijk, MM Magiera, C Bosc, JC Deloulme, A Bosson, ... Cell 143 (4), 564-578, 2010 | 369 | 2010 |
Expression of the cyclin-dependent kinase inhibitor p16 in Alzheimer's disease TAL Rödel, U Gärtner, M Holzer Neuroreport 7 (18), 3047-3050, 1996 | 300 | 1996 |
Tau oligomers impair artificial membrane integrity and cellular viability K Flach, I Hilbrich, A Schiffmann, U Gärtner, M Krüger, M Leonhardt, ... Journal of Biological Chemistry 287 (52), 43223-43233, 2012 | 223 | 2012 |
Expression of endothelial and inducible NOS-isoforms is increased in Alzheimer’s disease, in APP23 transgenic mice and after experimental brain lesion in rat: evidence for an … HJ Lüth, M Holzer, U Gärtner, M Staufenbiel, T Arendt Brain research 913 (1), 57-67, 2001 | 215 | 2001 |
Alzheimer-related τ-pathology in the perforant path target zone and in the hippocampal stratum oriens and radiatum correlates with onset and degree of dementia DR Thal, M Holzer, U Rüb, G Waldmann, S Günzel, D Zedlick, R Schober Experimental neurology 163 (1), 98-110, 2000 | 189 | 2000 |
Pseudophosphorylation of tau protein alters its ability for self‐aggregation C Haase, JT Stieler, T Arendt, M Holzer Journal of neurochemistry 88 (6), 1509-1520, 2004 | 183 | 2004 |
Paired helical filament-like phosphorylation of tau, deposition of β/A4-amyloid and memory impairment in rat induced by chronic inhibition of phosphatase 1 and 2A T Arendt, M Holzer, R Fruth, MK Brückner, U Gärtner Neuroscience 69 (3), 691-698, 1995 | 178 | 1995 |
Increased expression and subcellular translocation of the mitogen activated protein kinase kinase and mitogen-activated protein kinase in Alzheimer's disease T Arendt, M Holzer, A Grossmann, D Zedlick, MK Bru Neuroscience 68 (1), 5-18, 1995 | 159 | 1995 |
Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy P Delobel, I Lavenir, G Fraser, E Ingram, M Holzer, B Ghetti, ... The American journal of pathology 172 (1), 123-131, 2008 | 149 | 2008 |
Neuronal expression of cycline dependent kinase inhibitors of the INK4 family in Alzheimer's disease T Arendt, M Holzer, U Gärtner Journal of neural transmission 105, 949-960, 1998 | 148 | 1998 |
Aberrant expression of nNOS in pyramidal neurons in Alzheimer's disease is highly co-localized with p21ras and p16INK4a HJ Lüth, M Holzer, HJ Gertz, TH Arendt Brain research 852 (1), 45-55, 2000 | 130 | 2000 |
Elevated expression of p21ras is an early event in Alzheimer's disease and precedes neurofibrillary degeneration U Gärtner, M Holzer, T Arendt Neuroscience 91 (1), 1-5, 1999 | 129 | 1999 |
Phosphorylation of tau, Aβ-formation, and apoptosis after in vivo inhibition of PP-1 and PP-2A T Arendt, M Holzer, R Fruth, MK Brückner, U Gärtner Neurobiology of aging 19 (1), 3-13, 1998 | 116 | 1998 |
Phylogenetic diversity of the expression of the microtubule-associated protein tau: implications for neurodegenerative disorders C Janke, M Beck, T Stahl, M Holzer, K Brauer, V Bigl, T Arendt Molecular brain research 68 (1-2), 119-128, 1999 | 113 | 1999 |
Tenascin-R promotes assembly of the extracellular matrix of perineuronal nets via clustering of aggrecan M Morawski, A Dityatev, M Hartlage-Rübsamen, M Blosa, M Holzer, ... Philosophical Transactions of the Royal Society B: Biological Sciences 369 …, 2014 | 102 | 2014 |
Abnormally phosphorylated tau protein in Alzheimer's disease: heterogeneity of individual regional distribution and relationship to clinical severity M Holzer, HP Holzapfel, D Zedlick, MK Brückner, T Arendt Neuroscience 63 (2), 499-516, 1994 | 102 | 1994 |