Naturally occurring p16Ink4a-positive cells shorten healthy lifespan DJ Baker, BG Childs, M Durik, ME Wijers, CJ Sieben, J Zhong, ... Nature 530 (7589), 184-189, 2016 | 2578 | 2016 |
The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs YI Zhu, T Tchkonia, T Pirtskhalava, AC Gower, H Ding, N Giorgadze, ... Aging cell 14 (4), 644-658, 2015 | 2162 | 2015 |
Senolytics improve physical function and increase lifespan in old age M Xu, T Pirtskhalava, JN Farr, BM Weigand, AK Palmer, MM Weivoda, ... Nature medicine 24 (8), 1246-1256, 2018 | 1853 | 2018 |
Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice CM Roos, B Zhang, AK Palmer, MB Ogrodnik, T Pirtskhalava, NM Thalji, ... Aging cell 15 (5), 973-977, 2016 | 718 | 2016 |
Consequences of exercise-induced respiratory muscle work JA Dempsey, L Romer, J Rodman, J Miller, C Smith Respiratory physiology & neurobiology 151 (2-3), 242-250, 2006 | 506 | 2006 |
Targeting senescent cells alleviates obesity‐induced metabolic dysfunction AK Palmer, M Xu, YI Zhu, T Pirtskhalava, MM Weivoda, CM Hachfeld, ... Aging cell 18 (3), e12950, 2019 | 500 | 2019 |
Impact of aortic valve calcification, as measured by MDCT, on survival in patients with aortic stenosis: results of an international registry study MA Clavel, P Pibarot, D Messika-Zeitoun, R Capoulade, J Malouf, ... Journal of the American College of Cardiology 64 (12), 1202-1213, 2014 | 497 | 2014 |
Dysregulation of antioxidant mechanisms contributes to increased oxidative stress in calcific aortic valvular stenosis in humans JD Miller, Y Chu, RM Brooks, WE Richenbacher, R Peña-Silva, ... Journal of the American College of Cardiology 52 (10), 843-850, 2008 | 446 | 2008 |
Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence R Anderson, A Lagnado, D Maggiorani, A Walaszczyk, E Dookun, ... The EMBO journal 38 (5), e100492, 2019 | 416 | 2019 |
Calcific aortic valve stenosis: methods, models, and mechanisms JD Miller, RM Weiss, DD Heistad Circulation research 108 (11), 1392-1412, 2011 | 395 | 2011 |
Exercise prevents diet-induced cellular senescence in adipose tissue MJ Schafer, TA White, G Evans, JM Tonne, GC Verzosa, MB Stout, ... Diabetes 65 (6), 1606-1615, 2016 | 334 | 2016 |
A potent and specific CD38 inhibitor ameliorates age-related metabolic dysfunction by reversing tissue NAD+ decline MG Tarragó, CCS Chini, KS Kanamori, GM Warner, A Caride, ... Cell metabolism 27 (5), 1081-1095. e10, 2018 | 298 | 2018 |
Calcific aortic valve stenosis in old hypercholesterolemic mice RM Weiss, M Ohashi, JD Miller, SG Young, DD Heistad Circulation 114 (19), 2065-2069, 2006 | 259 | 2006 |
Respiratory system determinants of peripheral fatigue and endurance performance JA Dempsey, M Amann, LM Romer, JD Miller Medicine & Science in Sports & Exercise 40 (3), 457-461, 2008 | 240 | 2008 |
Quantification of GDF11 and myostatin in human aging and cardiovascular disease MJ Schafer, EJ Atkinson, PM Vanderboom, B Kotajarvi, TA White, ... Cell metabolism 23 (6), 1207-1215, 2016 | 228 | 2016 |
Senolytic drugs: reducing senescent cell viability to extend health span PD Robbins, D Jurk, S Khosla, JL Kirkland, NK LeBrasseur, JD Miller, ... Annual review of pharmacology and toxicology 61 (1), 779-803, 2021 | 222 | 2021 |
Skeletal muscle pump versus respiratory muscle pump: modulation of venous return from the locomotor limb in humans JD Miller, DF Pegelow, AJ Jacques, JA Dempsey The Journal of physiology 563 (3), 925-943, 2005 | 219 | 2005 |
Novel aspects of oxidative stress in cardiovascular diseases DD Heistad, Y Wakisaka, J Miller, Y Chu, R Pena-Silva Circulation Journal 73 (2), 201-207, 2009 | 198 | 2009 |
Cardiac output during exercise by the open circuit acetylene washin method: comparison with direct Fick BD Johnson, KC Beck, DN Proctor, J Miller, NM Dietz, MJ Joyner Journal of applied physiology 88 (5), 1650-1658, 2000 | 190 | 2000 |
Lowering plasma cholesterol levels halts progression of aortic valve disease in mice JD Miller, RM Weiss, KM Serrano, RM Brooks, CJ Berry, K Zimmerman, ... Circulation 119 (20), 2693-2701, 2009 | 176 | 2009 |