A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the αIIbβ3 integrin and cosegregates dominantly … C Ghevaert, A Salsmann, NA Watkins, E Schaffner-Reckinger, A Rankin, ... Blood, The Journal of the American Society of Hematology 111 (7), 3407-3414, 2008 | 110 | 2008 |
Distinct involvement of β3 integrin cytoplasmic domain tyrosine residues 747 and 759 in integrin-mediated cytoskeletal assembly and phosphotyrosine signaling E Schaffner-Reckinger, V Gouon, C Melchior, S Plançon, N Kieffer Journal of Biological Chemistry 273 (20), 12623-12632, 1998 | 106 | 1998 |
The talin rod IBS2 α-helix interacts with the β3 integrin cytoplasmic tail membrane-proximal helix by establishing charge complementary salt bridges S Rodius, O Chaloin, M Moes, E Schaffner-Reckinger, I Landrieu, ... Journal of biological chemistry 283 (35), 24212-24223, 2008 | 76 | 2008 |
A new functional role of the fibrinogen RGD motif as the molecular switch that selectively triggers integrin αIIbβ3-dependent RhoA activation during cell spreading A Salsmann, E Schaffner-Reckinger, F Kabile, S Plançon, N Kieffer Journal of Biological Chemistry 280 (39), 33610-33619, 2005 | 66 | 2005 |
Quantitative kinetic study of the actin-bundling protein L-plastin and of its impact on actin turn-over Z Al Tanoury, E Schaffner-Reckinger, A Halavatyi, C Hoffmann, M Moes, ... PloS one 5 (2), e9210, 2010 | 61 | 2010 |
The actin filament cross‐linker L‐plastin confers resistance to TNF‐α in MCF‐7 breast cancer cells in a phosphorylation‐dependent manner B Janji, L Vallar, ZA Tanoury, F Bernardin, G Vetter, ... Journal of cellular and molecular medicine 14 (6a), 1264-1275, 2010 | 50 | 2010 |
RGD, the Rho’d to cell spreading A Salsmann, E Schaffner-Reckinger, N Kieffer European journal of cell biology 85 (3-4), 249-254, 2006 | 47 | 2006 |
L‐plastin Ser5 phosphorylation in breast cancer cells and in vitro is mediated by RSK downstream of the ERK/MAPK pathway MJ Lommel, P Trairatphisan, K Gäbler, C Laurini, A Muller, T Kaoma, ... The FASEB Journal 30 (3), 1218-1233, 2016 | 42 | 2016 |
HPA-1a phenotype–genotype discrepancy reveals a naturally occurring Arg93Gln substitution in the platelet β3 integrin that disrupts the HPA-1a epitope NA Watkins, E Schaffner-Reckinger, DL Allen, GJ Howkins, NHC Brons, ... Blood, The Journal of the American Society of Hematology 99 (5), 1833-1839, 2002 | 40 | 2002 |
Green fluorescent protein (GFP) tagged to the cytoplasmic tail of αIIb or β3 allows the expression of a fully functional integrin αIIbβ3: effect of β3GFP on αIIbβ3 ligand binding S Plançon, MC MOREL-KOPP, E Schaffner-Reckinger, P CHEN, ... Biochemical Journal 357 (2), 529-536, 2001 | 37 | 2001 |
Overexpression of the partially activated αIIbβ3D723H integrin salt bridge mutant downregulates RhoA activity and induces microtubule‐dependent proplatelet–like extensions in … E SCHAFFNER‐RECKINGER, A Salsmann, N Debili, J Bellis, J De Mey, ... Journal of Thrombosis and Haemostasis 7 (7), 1207-1217, 2009 | 28 | 2009 |
The effect of recombinant IgG antibodies against the leucine-33 form of the platelet β3 integrin (HPA-1a) on platelet function L Joutsi-Korhonen, S Preston, PA Smethurst, M IJsseldijk, ... Thrombosis and haemostasis 91 (04), 743-754, 2004 | 28 | 2004 |
Angiotensin II regulates phosphorylation of actin-associated proteins in human podocytes LK Schenk, A Möller-Kerutt, R Klosowski, D Wolters, E Schaffner, T Weide, ... FASEB Journal, 2017 | 21 | 2017 |
Expanding the interactome of TES by exploiting TES modules with different subcellular localizations S Sala, M Van Troys, S Medves, M Catillon, E Timmerman, A Staes, ... Journal of Proteome Research 16 (5), 2054-2071, 2017 | 15 | 2017 |
L-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasiveness RAC Machado, D Stojevski, S De Landtsheer, P Lucarelli, A Baron, ... Cell Communication and Signaling 19, 1-22, 2021 | 11 | 2021 |
Eliminating oncogenic RAS: back to the future at the drawing board CL Steffen, P Kaya, E Schaffner-Reckinger, D Abankwa Biochemical Society Transactions 51 (1), 447-456, 2023 | 10 | 2023 |
Evidence from site-directed mutagenesis that the cytoplasmic domain of the β3 subunit influences the conformational state of the αvβ3 integrin ectodomain E Schaffner-Reckinger, NHC Brons, N Kieffer Thrombosis and haemostasis 85 (04), 716-723, 2001 | 10 | 2001 |
Delineating the tes interaction site in zyxin and studying cellular effects of its disruption E Hadzic, M Catillon, A Halavatyi, S Medves, M Van Troys, M Moes, ... PLoS One 10 (10), e0140511, 2015 | 9 | 2015 |
The actin-bundling protein L-plastin—A double-edged sword: Beneficial for the immune response, maleficent in cancer E Schaffner-Reckinger, RAC Machado International Review of Cell and Molecular Biology 355, 109-154, 2020 | 8 | 2020 |
The PET and LIM1-2 domains of testin contribute to intramolecular and homodimeric interactions S Sala, M Catillon, E Hadzic, E Schaffner-Reckinger, M Van Troys, ... PLoS One 12 (5), e0177879, 2017 | 7 | 2017 |