Christopher Illingworth
Christopher Illingworth
Department of Genetics, University of Cambridge
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High-definition reconstruction of clonal composition in cancer
A Fischer, I Vázquez-García, CJR Illingworth, V Mustonen
Cell reports 7 (5), 1740-1752, 2014
High-resolution mapping of complex traits with a four-parent advanced intercross yeast population
FA Cubillos, L Parts, F Salinas, A Bergström, E Scovacricchi, A Zia, ...
Genetics 195 (3), 1141-1155, 2013
EMu: probabilistic inference of mutational processes and their localization in the cancer genome
A Fischer, CJR Illingworth, PJ Campbell, V Mustonen
Genome biology 14 (4), 1-10, 2013
Single-cell RNA-seq reveals hidden transcriptional variation in malaria parasites
AJ Reid, AM Talman, HM Bennett, AR Gomes, MJ Sanders, ...
Elife 7, e33105, 2018
Criteria for confirming sequence periodicity identified by Fourier transform analysis: Application to GCR2, a candidate plant GPCR?
CJR Illingworth, KE Parkes, CR Snell, PM Mullineaux, CA Reynolds
Biophysical chemistry 133 (1-3), 28-35, 2008
Classical polarization in hybrid QM/MM methods
CJR Illingworth, SR Gooding, PJ Winn, GA Jones, GG Ferenczy, ...
The Journal of Physical Chemistry A 110 (20), 6487-6497, 2006
Quantifying selection acting on a complex trait using allele frequency time series data
CJR Illingworth, L Parts, S Schiffels, G Liti, V Mustonen
Molecular biology and evolution 29 (4), 1187-1197, 2012
Computational studies of family A and family B GPCRs
S Vohra, SV Chintapalli, CJR Illingworth, PJ Reeves, PM Mullineaux, ...
Biochemical Society Transactions 35 (4), 749-754, 2007
Many-body effects and simulations of potassium channels
CJ Illingworth, C Domene
Proceedings of the Royal Society A: Mathematical, Physical and Engineering …, 2009
Assessing the role of polarization in docking
CJR Illingworth, GM Morris, KEB Parkes, CR Snell, CA Reynolds
The Journal of Physical Chemistry A 112 (47), 12157-12163, 2008
In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization
CD Shaw, J Lonchamp, T Downing, H Imamura, TM Freeman, JA Cotton, ...
Molecular Microbiology 99 (6), 1134-1148, 2016
Distinguishing driver and passenger mutations in an evolutionary history categorized by interference
CJR Illingworth, V Mustonen
Genetics 189 (3), 989-1000, 2011
Identifying selection in the within-host evolution of influenza using viral sequence data
CJR Illingworth, A Fischer, V Mustonen
PLoS Comput Biol 10 (7), e1003755, 2014
The effective rate of influenza reassortment is limited during human infection
AS Leonard, MT McClain, GJD Smith, DE Wentworth, RA Halpin, X Lin, ...
PLoS Pathogens 13 (2), e1006203, 2017
Components of selection in the evolution of the influenza virus: linkage effects beat inherent selection
CJR Illingworth, V Mustonen
PLoS Pathog 8 (12), e1003091, 2012
Addicted? Reduced host resistance in populations with defensive symbionts
J Martinez, R Cogni, C Cao, S Smith, CJR Illingworth, FM Jiggins
Proceedings of the Royal Society B: Biological Sciences 283 (1833), 20160778, 2016
Inferring genome-wide recombination landscapes from advanced intercross lines: application to yeast crosses
CJR Illingworth, L Parts, A Bergström, G Liti, V Mustonen
PloS one 8 (5), e62266, 2013
Effects of point mutations in pVHL on the binding of HIF‐1α
C Domene, CJR Illingworth
Proteins: Structure, Function, and Bioinformatics 80 (3), 733-746, 2012
Computational Studies on Polarization Effects and Selectivity in K+ Channels
CJR Illingworth, S Furini, C Domene
Journal of Chemical Theory and Computation 6 (12), 3780-3792, 2010
Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus
SR Doyle, CJR Illingworth, R Laing, DJ Bartley, E Redman, A Martinelli, ...
BMC genomics 20 (1), 218, 2019
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